Nu logo main

Recruiting Studies

Title Investigator Keywords
Northwestern Scleroderma Program Patient Registry Hinchcliff, Monique E scleroderma , skin fibrosis , systemic sclerosis , autoimmune
PCCTC-c16-170: IRONMAN: International Registry for Men with Advanced Prostate Cancer Kundu, Shilajit D Prostate Cancer
A Study of the Efficacy and Safety of Etrolizumab in Ulcerative Colitis Patients Who Are Refractory to or Intolerant of TNF Inhibitors Hanauer, Stephen Inflammatory Bowel Disease, IBD, Ulcerative Colitis, Etrolizumab, Tnf inhibitors, gastroenteritis
The ENRGISE Pilot Study McDermott, Mary Douglas Mobility, Walking difficulty, Inflammation, Losartan, Omega-3 fish oil
ECOG-ACRIN 8143 A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Localized Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC) Sosman, Jeffrey
Genomic Response Analysis of Heart Failure Therapy in African Americans Anderson, Allen heart failure
Cocoa to Improve Walking Performance in Peripheral Artery Disease: The COCOA-PAD Study McDermott, Mary Douglas peripheral artery disease, cardiovascular disease, cocoa, atherosclerosis
Transthyretin-Associated Amyloidoses Outcome Survey (THAOS) Shah, Sanjiv J TRANSTHYRETIN, AMYLOIDOSIS, TRANSTHYRETIN AMYLOIDOSIS
Evaluation of the Safety and Performance of The Twelve Intrepid™ Transcatheter Mitral Valve Replacement System in High Risk Patients with Severe, Symptomatic Mitral Regurgitation - The Twelve Intrepid™ TMVR Pilot Study McCarthy, Patrick M Valve Disease, TMVR, Mitral Valve, Mitral Regurgitation, Transcatheter
Predictive Ability of Gene Expression Signatures in Skin as SSc Biomarkers Hinchcliff, Monique E scleroderma , inflammatory, skin fibrosis
The Effect of Neuraxial Analgesia on Maternal Breastfeeding Wong, Cynthia A Epidural Labor Analgesia, Pain, Infant, Breastfeeding
Intranasal oxytocins effect on facial affect discrimination in schizophrenia Goldman, Morris B
Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE) Rodriguez Alvarez, Heron Rodriguez thoracic aneurysm, thoracic aortic aneurysms, Thoracic Endovascular Aneurysm Repair (TEVAR), Talent Thoracic Stent Graft
Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients Gallon, Lorenzo Sirolimus, Rapamune, Immunosuppression, Renal allograft function, Lymphocytes function
Lower extremity motor coordination with and without nervous system injury Sukal Moulton, Theresa Sukal
Assessment of the WATCHMAN(TM) Device in Patients Unsuitable for Oral Anticoagulation Knight, Bradley Paul atrial fibrillation, afib, anticoagulation, heart rhythm disorders, LAA, Left Atrial Appendage , LAAC, Left Atrial Appendage Closure
Transverse Abdominis Plane (TAP) Block After Cesarean Delivery Yaghmour, Edward Talaat Cesarean Delivery, Ropivicaine, TAP block
HLA-Identical Sibling Renal Transplant Tolerance Leventhal, Joseph R Transplants, Kidney Transplantation, Immunosuppression, HLA Antigens, Stem Cells, Bone Marrow
Chicago Lupus Database Ramsey-Goldman, Rosalind lupus
Characteristics of the Stretch Reflex Response in Various Joints Perreault, Eric
DERMATOLOGY TISSUE ACQUISITION AND REPOSITORY West, Dennis P biopsy, tissue, biorepository, dermatology
Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Salem, Riad adult primary hepatocellular carcinoma, localized unresectable adult primary liver cancer, advanced adult primary liver cancer
Radiolabeled Glass Beads in Treating Patients With Metastatic Liver Cancer That Cannot Be Removed by Surgery Salem, Riad liver metastases, advanced adult primary liver cancer
A Study to Evaluate Chronic Hepatitis C Infection in Adult Transplant Recipients Levitsky, Josh Chronic Hepatitis, Hepatitis C Virus, Hepatitis C Genotype 1, Interferon-Free, Liver Transplant, Renal Transplant
A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Mitral Bioprosthetic Valve Malaisrie, S Chris Chris mitral valve, mitral regurgitation, transcatheter, Transcatheter Heart Valve, TMVR, PARTNER 3, failing valve, failing bioprosthetic valve
INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated heart failure (INVESTED) Mutharasan, R Heart Failure, Flu Shot, Flu vaccine, Influenza, influenza vaccine , Myocardial Infarction, Heart Attack
A Phase 3 Multicenter, Randomized, Double-Blind, Extension Study to Evaluate the Safety of Daily Oral Dosing of Tafamidis Meglumine (PF-06291826) 20 mg or 80 mg in Subjects Diagnosed With Transthyretin Cardiomyopathy (TTR-CM) Shah, Sanjiv J ATTR, Transthyretin, Tafamidis
NIH All of Us Research Program Precision Medicine Initiative® Precision Medicine Initiative Cohort Program Healthcare Provider Organization Enrollment Centers Greenland, Philip Precision Medicine, genetics, individualized medicine, health care, environment, lifestyle, biology, biobank, technology, behavior
A Multicenter Group to Study Acute Liver Failure. Long-term Outcomes of Acute Liver Failure Study Group Patients Ganger, Daniel R acute liver failure, acute liver injury
Reduction in Allergic Antibody in Human Allergic Subjects Greenberger, Paul Allen
Real Life Multimarker Monitoring in Patients with Heart Failure (REALIsM-HF) Shah, Sanjiv J Heart Failure, HFpEF, HFrEF
Clinical Protocol CV013020: A Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Cross-over Phase 2 Study of Continuous 5-Hour Intravenous Infusions of BMS-986231 in Patients with Heart Failure and Impaired Systolic Function Vorovich, Esther
An Open-Label, Multicenter Extension and Long-Term Observational Study in Patients Previously Enrolled in a Genentech- and/or F. Hoffman-La Roche LTD-Sponsored Atezolizumab Study. Mohindra, Nisha
A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABBV-744 in Subjects with Metastatic Castrate-Resistant Prostate Cancer (CRPC) and Relapsed/Refractory Acute Myeloid Leukemia (AML) Frankfurt, Olga
Mediators of Atherosclerosis in South Asians Living in America Kandula, Namratha R
DRUG 2215-CL-9100A Multicenter, Open-label Treatment Protocol of Gilteritinib (ASP2215) in Patients with FMS-like Tyrosine Kinase 3 (FLT3) Mutated Relapsed or Refractory Acute Myeloid Leukemia (AML) or FLT3-Mutated AML in Complete Remission (CR) with Minimal Residual Disease (MRD) Frankfurt, Olga
C1973-204 - A Multicenter, Randomized, Double-blind, Placebo controlled, Phase 2 Study Evaluating the Safety and Efficacy of Different Doses of IW-1973 over 12 Weeks in Patients with Heart Failure with Preserved Ejection Fraction Freed, Benjamin HFpEF
Alterations in Gene Expression in the Scleroderma Esophagus Hinchcliff, Monique E scleroderma , autoimmune , heartburn , GERD, systemic sclerosis, esophagus, inflammatory
SHAPE: Seeing the Heart with AI Powered Echo McCarthy, Patrick M
A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Aortic Bioprosthetic Valve Malaisrie, S Chris Chris TAVR, Aortic Valve Replacement , Aortic Stenosis, PARTNER, PARTNER 3, valve in valve, AVIV
(xIRB NCI CIRB) SWOG 1609 DART: Dual Anti-CTLA-4 and Anti-PD-1 blockade in Rare Tumors Chae, Young Kwang
A Phase 3 Open-label, Multicenter Study to Evaluate the Long-term Safety and Tolerability of Inhaled LIQ861 (Treprostinil) in Pulmonary Arterial Hypertension (WHO Group 1) Patients Rich MD, Stuart pah, pulmonary arterial hypertension , LTI-301
TRANSFORM-HF: ToRsemide compArisoN with furoSemide FOR Management of Heart Failure Rich, Jonathan torsemide, furosemide
17-518: The MitraClip® EXPAND Study A Contemporary, Prospective Study Evaluating Real-world Experience of Performance and Safety for the Next Generation of MitraClip® Devices Ricciardi, Mark MitraClip, Mitral Valve, Mitral Regurgitation, TMVR, Transcatheter Mitral Valve Repair
Dapagliflozin EFfect on symptoms and bIomarkers iN patiEnts with Heart Failure (DEFINE-HF) Mutharasan, R heart failure
Communication Bridge: Using Internet-Based Speech Therapy to Improve Quality of Life and Access to Care Rogalski, Emily Joy
Second Curettage in Treating Patients With Persistent Non-Metastatic Gestational Trophoblastic Tumor Shahabi, Shohreh nonmetastatic gestational trophoblastic tumor, hydatidiform mole
Platelet-Orientated Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial Bernstein, Richard A
Self Administered Cognitive Behavior Therapy for Irritable Bowel Syndrome Keefer, Laurie
Neural Mechanisms in Sensory Reception and Processing in the Healthy Adult (VA RR&D Grant # B3302K) Pape, Theresa L Bender L
Alzheimer's Disease Core Center Mesulam, Marek-Marsel
Screening For a Registry (Database) and Future Participation In Asthma and Chronic Obstructive Lung Disease (COPD) Clinical Research Studies Kalhan, Ravi ephysema, chronic bronchitis, shortness of breath, coughing, chest tightness, lungs, inhaler
Development of New MRI Protocols Parrish, Todd B
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression Simuni, Tatyana Parkinson, Bio-markers, Neurodegenerative disorder, Imaging, Prodromal
The Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis Malaisrie, S Chris Chris Center for Heart Valve Disease, Aortic Valve, Aortic Stenosis, AVR, TAVR, transcatheter , PARTNER, PARTNER 3, SAPIEN, THV
CENTER FOR BEHAVIORAL INTERVENTION TECHNOLOGIES (CBITs) RESEARCH SUBJECT RECRUITMENT REGISTRY Mohr, David C Depression, Anxiety, Smartphone, Health, Technology, Internet
The ANSWER Program® : American Norditropin® Studies: Web Enabled Research (StudyID: HGH-2149); An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin® (Human Growth Hormone) Molitch, Mark E
Serial Blood and Urine Monitoring Study in Kidney Transplant Recipients Friedewald, John J Transplantation, Kidney, Biological Markers
Exceptional Cognitive Aging: Neuropsychologic, Anatomic and Pathologic Correlates Rogalski, Emily Joy
An Exploratory Phase II Study to Determine the Tolerability, Safety, and Activity of a Novel Vasopressin 1a Receptor Antagonist (SRX246) in Irritable Subjects with Huntington's Disease (HD) Bega, Danny irritability, behavioral problems, Huntington's, HD
cIRB: Topiramate as a disease altering therapy for Cryptogenic Sensory Peripheral Neuropathy (CSPN) Menichella, Daniela Pain, sensory loss, imbalance, obesity
EHR-based Health Literacy Strategy to Promote Medication Therapy Management Persell, Stephen D
Enroll-HD: A Prospective Registry Study in a Global Huntington’s Disease Cohort Bega, Danny Huntington's disease, Registry Study
Incidence of Headache Following an Unintentional Dural Puncture Peralta, Feyce Postdural puncture headache, Intrathecal morphine, Intrathecal catheter, Headache, Labor and delivery, Unintentional dural puncture
NU 16H07: Phase II Trial of Pembrolizumab in Combination with ICE Salvage Chemotherapy for Relapsed/Refractory Hodgkin Lymphoma Winter, Jane Norma Hodgkin Lymphoma; Immunotherapy; , Pembrolizumab; , Keytruda; , Clinical trial, Research, Lymphoma, phase 2, relapse (cancer has come back); refractory (cancer has not responded)
Macular Edema Ranibizumab v. Intravitreal anti-inflammatory Therapy (MERIT) Trial Koreishi, Anjum
(xIRB) A Phase 2, Randomized, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Filgotinib in Subjects with Active Non infectious Uveitis Koreishi, Anjum
ECOG 1910: A Phase III Randomized Trial of Blinatumomab for Newly Diagnosed BCR-ABL-negative B lineage Acute Lymphoblastic Leukemia in Adults. Dinner, Shira
NU 16H08: Phase II study of PET-directed frontline therapy with pembrolizumab and AVD for patients with classical Hodgkin lymphoma Winter, Jane Norma classical hodgkin lymphoma; immunotherapy; Pembrolizumab; Keytruda; Clinical trial; Research; phase 2
Role Functioning Changes in New Onset Symptoms Cronenwett, Will J confused , depression, bipolar, psychosis, mania, schizophrenia, relationship issues, school, work, anxiety, hallucinations, concentration, racing thoughts , distraction
(CIRB)-A Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 Delivered by Single or Multi-Dose Intravitreal Injection(s) to Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Volpe, Nicholas ophthalmology, NAION, VOLPE
Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma Pro, Barbara
nuMoM2b Heart Health Study Grobman, William A Cardiovascular disease, Pregnant women, Nulliparity, Pregnancy outcomes, Pregnancy complications, Sleep disordered breathing
Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis Brieva, Joaquin C videocapillaroscopy, psoriasis, systemic agent
Improving Hypertension Using a Smartphone-Enabled Personal Control Program: Persell, Stephen D
Set Your GOAL: Engaging GO/No-Go Active Learning Gollan, Jacqueline K decision making, depression anxiety
Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy Wunderink, Richard G sepsis
Microbiomes of Pelvic Pain Klumpp, David
Motivational Interviewing and Physical Activity in Parkinson’s Disease Ehrlich-Jones, Linda S Parkinson's Disease, Parkinson's, Exercise, Physical Activity
Home sleep and circadian phase: mediators of racial disparities in diabetes risk Knutson, Kristen sleep, circadian rhythms, diabetes, cardiovascular disease
A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients Luo, Xunrong Diabetes, Islet, Pancreas, Hypoglycemia, T1D, Transplant
Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer Mulcahy, Mary Frances
A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV) Grobman, William A Perinatology, Cytomegalovirus immune globulin, Cytogam, CMVIG infusions, primary CMV infection in pregnancy
Sleep Disturbance and Metabolic Syndrome Zee, Phyllis C overweight, high blood pressure, high blood sugar, trouble falling or staying asleep, poor sleep quality
Cardiometabolic outcomes with light exposure during sleep Zee, Phyllis C
Circadian rhythms and epilepsy: a prospective study Zee, Phyllis C Generalized seizures and focal seizures, sleep-wake and circadian rhythm patterns in patients with epilepsy
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Active Comparator, Parallel-Group Study of the Efficacy and Safety of Lemborexant in subjects 55 Years and Older with Insomnia Disorder Abbott, Sabra Trouble falling asleep, Trouble staying asleep, Insomnia, Age 55 or older
Annular ReduCtion for Transcatheter Treatment of Insufficient Mitral ValvE (ACTIVE): A prospective, multicenter, randomized, controlled pivotal trial to assess transcatheter mitral valve repair with Edwards Cardioband System and guideline directed medical therapy (GDMT) compared to GDMT alone in patients with functional mitral regurgitation (FMR) and heart failure. Davidson, Charles J Mitral Valve, mitral regurgiation, Heart Valve, Valve Disease , functional MR, Cardioband, transcatheter, TMVR, mitral valve repair, MVR
A multicenter, international, open-label, safety study of ND0612, a solution of levodopa/carbidopa delivered via a pump system as a continuous subcutaneous infusion in subjects with advanced Parkinson's Disease (BeyoND) Simuni, Tatyana
Multicenter, randomized, double-blind, placebo controlled study to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of GZ/SAR402671 in patients with early-stage Parkinson’s disease carrying a GBA mutation or other pre-specified variant. Simuni, Tatyana
A Study to Show That Treatment With Denosumab is as Good as Treatment With Risedronate in Subjects Who Are Starting to Take or Currently Taking Glucocorticoids. Schnitzer, Thomas J GIOP, Glucocorticoid, osteporosis, denosumab, BMD, Bone Mineral Density
GLORIA-AF Registry Program - Second and Third Phases Bernstein, Richard A
Stepped Telemental Health Care Intervention for Depression Mohr, David C Depression, Cognitive Behavioral Therapy, Internet, Telemedicine
Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence Santa-Maria, Cesar HER2, low or intermediate, breast cancer, node-positive tumors
3D Echocardiographic and Doppler Data as a Comparison to Cardiac Magnetic Resonance (CMR) Imaging Thomas, James echocardiography , doppler, CMR
Safety and Efficacy Study of Dronabinol to Treat Obstructive Sleep Apnea Zee, Phyllis C
Targeting Siglecs in Disease supported by NIH Grant R01 AI072265 Targeting Siglec-8/-F to treat eosinophil and mast cell related disorders and P01 HL107151 Glycobiology of Inflammatory Lung Diseases: Project 1 and U19 AI136443 Using Siglecs and Their Ligands to Treat Allergic Diseases: Project 1 and Core B. Bochner, Bruce
Lidocaine and Prevention of Chronic Pain De Oliveira, Gildasio S Surgery, Breast, Pain, Chronic Pain, Lidocaine, Anesthesia, Gynecologic, Urologic
ANTLER Pilot Intervention Ramsey-Goldman, Rosalind
Genome Research in African American Scleroderma Patients (GRASP) Varga, John systemic sclerosis, scleroderma, genetics, DNA, genes, African Americans
Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study Kalhan, Ravi COPD, RePneu
An Observational Study of Hepatitis C Virus in Pregnancy Grobman, William A observational study, 2 year child follow-up, known HCV positive
Ultrasound-guided Adductor Canal Block for Total Knee Replacement Nader, Antoun
Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Goldstein, Debra
(xIRB NCI) ECOG-ACRIN 4151: A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma in Minimal Residual Disease-Negative First Complete Remission Winter, Jane Norma
(CIRB) A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Effect of Long-term Treatment with BELVIQ (lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects with Cardiovascular Disease or Multiple Cardiovascular Risk Factors Kushner, Robert F
Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM) Mohr, David C Android, Smartphone Apps, Depression, Anxiety
SRL (Sirolimus) Withdrawal Levitsky, Josh Liver Transplant, Sirolimus, Rapamune, Immunosuppressant Therapy, Withdrawal
Impact of autoimmunity on olfaction in patients with chronic sinusitis with nasal polyposis (CRSwNP) Tan, Bruce Kuang-Huay K
International GBS Outcome Study (IGOS) A prospective INC study on clinical and biological predictors of disease course and outcome in GBS Ajroud-Driss, Senda
Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia Wunderink, Richard G Gram-negative pneumonia, Intubation, Mechanical ventilation, Amikacin
Study to Evaluate the Safety and Efficacy of Dermal Injections of JVS-100 Given to Adults Receiving Median Sternotomy McCarthy, Patrick M Cicatrix, Wound healing
(xIRB NCI) SWOG 1605: Phase II Trial of Atezolizumab in BCG-Unresponsive Non-Muscle Invasive Bladder Cancer Meeks, Joshua J
A PHASE 3, PLACEBO CONTROLLED, DOUBLE-BLIND, RANDOMIZED, CLINICAL STUDY TO DETERMINE EFFICACY, SAFETY AND TOLERABILITY OF PULSED, INHALED NITRIC OXIDE (iNO) VERSUS PLACEBO IN SYMPTOMATIC SUBJECTS WITH PULMONARY ARTERIAL HYPERTENSION (PAH): INOvation-1 Rich MD, Stuart pulmonary arterial hypertension, PAH, heart failure, Inhaled Nitric Oxide, INOpulse, INOvation
Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery McCarthy, Robert J
Pilot study on the effect of endometrial injury in patients undergoing in vitro fertilization (IVF) Barnes, Randall
FTC/RPV/TDF on T-Cell Activation, CD4 Cell Count, Inflammatory Biomarkers and Viral Reservoir Taiwo, Babafemi O
The Genetics of Prostate Cancer in Active Surveillance Kundu, Shilajit D prostate cancer, active surveillance, PSA
Northwestern Chronic Rhinosinusitis (CRS) Subject Registry Tan, Bruce Kuang-Huay K
A Prospective, Multi-Center Trial Evaluating the Effectiveness of the V.A.C. Ulta Negative Pressure Wound Therapy System With V.A.C. VeraFlo Dressing System in Operatively Debrided Wounds Galiano, Robert D
Evaluate the Safety and Efficacy of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis Bhorade, Sangeeta Idiopathic Pulmonary Fibrosis, IPF, Idiopathic Interstitial Pneumonia, Interstitial Lung Disease, Lung Fibrosis
Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study Yilmaz, Meltem QOR-40, Pain, Hypoxia, Gastric Surgery, Obesity, Ketamine
Prostatic Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia (BPH) Salem, Riad Prostate Artery Embolization, PAE, Benign Prostatic Hyperplasia, BPH, Lower Urinary Tract Symptoms, LUTS
Pregnant Women Taking Lamictal for Bipolar Disorder Clark, Crystal pregnant, bipolar, lamotrigine, lamictal, women, female
Evaluation of Centration of Intraocular Lens With Two Settings for Capsulorhexis With Femtosecond Laser Basti, Surendra capsulorhexis, IOL centration
Epigenetic Markers of Bladder Cancer Progression Meeks, Joshua J bladder cancer, urothelial carcinoma
Vitamin D and Type 2 Diabetes Study Neff, Lisa M Prediabetes, Vitamin D
An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD Singhal, Seema Multiple myeloma, Daratumumab, Proteasome inhibitor, Immunomodulatory drug, IMiD
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery Donnelly, Eric
Evaluation of operative versus non-operative management of common hind foot disorders Kadakia, Anish
Biomarkers of Inflammation in Perinatal Depression in Women Undergoing Scheduled Cesarean Delivery Miller, Emily
Warren Wright Adolescent Center Study #1 Breiter, Hans
Brain imaging-based strategies for treating urological chronic pelvic pain syndrome (UCPPS) pain Apkarian, Apkar
The effects of capsinoids on brown adipose tissue recruitment and activation in obesity Neff, Lisa M weight loss, brown fat
Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) Ganger, Daniel R hepatic encephalopathy, hyperammonemia, cirrhosis, ornithine phenylacetate, OCR-002
Oxytocin and Pain Sensitivity and Threshold Walega, David R Pain, Oxytocin
First-line Antimetabolites as Steroid-sparing Treatment Uveitis Pilot Trial Goldstein, Debra uveitis, antimetabolite, immunosuppressive, clinical trial
The Role of Circadian Dysfunction in Hepatic Encephalopathy in Patients with Cirrhosis Kim, Minjee Cirrhosis, End-stage liver disease, hepatic encephalopathy, sleep, circadian, cognitive impairment, dementia, transplant, insomnia
Daily Oral Regorafenib for Chemotherapy-Refractory, Metastatic and Locally Advanced Angiosarcoma Agulnik, Mark
Safety Study of VM202 to Treat Amyotrophic Lateral Sclerosis Sufit, Robert L ALS, Lou Gehrig's disease, neurodegenerative disease
Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy Greenberger, Paul Allen
A Study of ARRY-520 and Carfilzomib in Patients With Advanced Multiple Myeloma Singhal, Seema
Treatment for CI-DME in Eyes With Very Good VA Study Lyon, A Thayer Diabetic Macular Edema, anti-vascular endothelial growth factor
Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients With Moderate to Very Severe COPD Rosenberg, Sharon Reifler
The Study of an Investigational Drug, ALN-TTR02, for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis Ajroud-Driss, Senda RNAi therapeutic
Cytomegalovirus and BK Virus Nephropathy Biobank Cohort Study Ison, Michael G
A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System Davidson, Charles J Congestive Heart Failure Due to LV Systolic Dysfunction
A Prospective Study to Identify Risk Factors for Progressive Calcinosis in Patients with Systemic Sclerosis: A Scleroderma Clinical Trials Consortium Study Hinchcliff, Monique E scleroderma , calcinosis , calcinosis cutis , autoimmune , systemic sclerosis
A Phase 2a Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis Schnitzer, Thomas J Pain, Osteoarthritis, Synovitis, Knee
A5320: Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) Taiwo, Babafemi O hepatitis C, HIV, direct acting
A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS) Prabhakaran, Shyam
Safety and Efficacy of MK-5172 + MK-8742 in Participants With Chronic Hepatitis C and Chronic Kidney Disease (MK-5172-052) Ganger, Daniel R
Conjugated Estrogens/Bazedoxifene in Treating Patients With Ductal Carcinoma in Situ Undergoing Surgery Kulkarni, Swati
Parkinson’s Disease and Movement Disorders Center Biorepository Simuni, Tatyana Genetics, blood samples, skin sample, neurological conditions
Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer Kulik, Laura M Immunosuppressive Agents, Liver Transplantation, HCC
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy Sutton, Sarah H Pregnancy, Pharmacokinetics, Treatment Experienced
Tracking the evolution of spasticity in acute stroke. Suresh, Nina
Belatacept 3 Month Post Transplant Conversion Study Gallon, Lorenzo Kidney, Renal, Transplant, EBV, Immunosuppressants, Belatacept
Thighplasty of transfemoral amputee residual limbs to improve prosthesis fit and patient functional outcomes Kuiken, Todd A
Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation Jain, Manu CF
Sofosbuvir Plus Ribavirin For Acute Hepatitis C in HIV-infected Individuals (SWIFT-C) Taiwo, Babafemi O
An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer Yanez, Betina Breast Cancer, Cancer de Seno, Cancer de Mama, Latina, Hispana, Español, Sobreviviente, Cancer Survivor
A Phase I, Single Center Trial of Adoptive Immunotherapy With T-reg Adoptive Cell Transfer (TRACT) to Prevent Rejection in Living Donor Kidney Transplant Recipients Skaro, Anton I Kidney transplant, Regulatory T cells, Leukopheresis, Immune cells, Stem Cells, Tolerance
HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network Levitsky, Josh Hepatitis, Hepatitis C, HCV-TARGET, HCV, Observational Study
B-WELL-Mom (Breathe-Wellbeing, Environment, Lifestyle, and Lung Function) Grobman, William A Asthma, Pregnancy, Lung function, immune response
The Scleroderma Patient-Centered Intervention Network (SPIN) Cohort Varga, John scleroderma , skin disease , quality of life , skin fibrosis , autoimmune , systemic sclerosis , patient reported outcomes, PROs, support
Ex vivo interactions between high-density-like nanoparticles and human blood Thaxton, Colby S cholesterol, HDL, LDL
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD) Including GSPECT (Gated Single Photon Emission Computed Tomography) Carr, James Myocardial Perfusion Imaging
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC) Hanauer, Stephen Registry, Gastrointestinal Diseases, Inflammatory Bowel Diseases, Gastroenteritis, Adalimumab, Colitis, Ulcerative Colitis, Humira
EDIC Hearing Ancillary Study Molitch, Mark E
Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at High Risk of Acquiring HIV-1 Infection Chadwick, Ellen
Development of an eHealth-based Cognitive Behavioral Stress and Self-Management Intervention to Reduce Symptom Burden in HIV+ Gay and Bisexual Men and Trans Women Treated for Non-Metastatic Cancer Penedo, Frank J cancer , HIV, LGBT, gay, bisexual, trans, non-metastatic, localized
A Blanket Protocol to Study Oral Regorafenib in Patients With Refractory Liposarcoma, Osteogenic Sarcoma, and Ewing/Ewing-like Sarcomas Agulnik, Mark
A Study of CLR325 in Chronic Stable Heart Failure Patients. Wilcox, Jane Elizabeth Heart Failure, CLR325, Center for Heart Failure, Chronic Stable Heart Failure, IND
Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial Prabhakaran, Shyam stroke, diabetes, hyperglycemia
Can active elbow extension reduce shoulder loading in C5/C6 quadriplegia? Murray, Wendy M M.
Steroids In Eosinophil Negative Asthma Smith, Lewis J steroids, shortness of breath, wheezing, coughing, chest tightness, lungs, eosinophils
Use of Radiofrequency Ablation for RGB Salvage Komanduri, Srinadh RGB Salvage, RFA
Study to Evaluate the Safety and Efficacy of Two Drug Regimens in Subjects With Moderate to Severe Ulcerative Colitis Hanauer, Stephen Ulcerative Colitis, Inflammatory Bowel Disease, IBD, Gastroenteritis, Gastrointestinal Diseases, Adalimumab
A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix Grobman, William A women, cervical length of less than 30 millimeters, carrying twins
Neural representation of olfactory rewards in the human brain Kahnt, Thorsten
ASSOCIATION OF PAI-1 AND FGF23 IN PATIENTS WITH KIDNEY DISEASE Vaughan, Douglas E
A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with an Acute, Complicated Type B Aortic Dissection Malaisrie, S Chris Chris aortic dissection, type B, endovascular stent-graft
AdaptResponse Clinical Trial Lin, Albert AdaptivCRT, aCRT, center for heart rhythm disorders, LBBB
Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral Therapy Taiwo, Babafemi O
Staging Intracranial Hemodynamic Failure with MRI Ansari, Sameer Ahmad
Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis Hirano, Ikuo
LCH_Measuring Human BAT Volume and Activity by Quantitative and Functional MRI (2014-15761) Deng, Jie
Efficacy, Safety, Tolerability of Carbavance Compared to Best Available Therapy in Serious Infections Due to Carbapenem Resistant Enterobacteriaceae, in Adults Wunderink, Richard G
LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009) Kalhan, Ravi
Comparison of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 24 Weeks in Adults With Chronic Genotype 3 HCV Infection Flamm, Steven L Sofosbuvir, SOF/GS-5816, GS-5816, Hepatitis C, HCV, cirrhosis
Glycemic Control and Treatment Satisfaction Using Finesse Versus Pen for Initiating Bolus Insulin Dosing in Type 2 Diabetes Mellitus Patients Not Achieving Glycemic Targets on Basal Insulin With/Without Anti-Hyperglycemic Agents Molitch, Mark E
Noninvasive Manipulation of Hippocampal-Cortical Brain Networks and Memory Voss, Joel
Development of a Kidney Cancer Patient Outcomes Database Cella, David
Open Label Study to Evaluate Long Term Efficacy, Safety and Tolerability of Repeated Dosing in Subjects With Crohn's Disease and Who Participated and Successfully Completed M14-115 Hanauer, Stephen Crohn's Disease
Alliance A081105: Randomized Study of Erlotinib vs Observation in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC) Mohindra, Nisha
Neural Systems for the Dynamic Use of Memory Voss, Joel
PREVENtion of HeartMate II Pump Thrombosis Rich, Jonathan HeartMate II, heart assist device, pump thrombosis, hypercoagulable disorder, thrombus
Multi-site study of the efficacy of speech perception training for hearing aid users Souza, Pamela Elizabeth
Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients with Passive Hepatic Congestion Secondary to Congenital Heart Disease (CHD) or Cardiomyopathy Ganger, Daniel R congenital heart disease, cardiomyopathy, liver disease
Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia Wunderink, Richard G Ventilator-associated bacterial pneumonia, Hospital-acquired bacterial pneumonia, Pneumonia, Lung Diseases, Respiratory Tract Diseases, Respiratory Tract Infections, Infection, Ventilator-Induced Lung Injury, Lung Injury
Sofosbuvir/GS-5816 Fixed-Dose Combination in Adults With Chronic HCV Infection and Child-Pugh Class B Cirrhosis Flamm, Steven L
Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease Molitch, Mark E LCI699, Cushing's disease
Improving Outpatient Safety of Older Adults through Electronic Patient Portals Lindquist, Lee A caregiver, geriatrics, MyChart, senior , electronic patient portal
Freehand Ultrasound to Evaluate Scapular Kinematics in People With Paraplegia Dhaher, Yasin Y Ultrasound, Shoulder, Spinal Cord Injury, Fluoroscopy
Application of Targeted Reinnervation for People With Transradial Amputation Kuiken, Todd A Transradial amputee
Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection Flamm, Steven L Sofosbuvir, SOF/GS-5816, GS-5816, Hepatitis C, HCV, cirrhosis
A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD) Kalhan, Ravi umeclidinium, COPD, fluticasone furoate, triple therapy, vilanterol, exacerbation
A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection Flamm, Steven L Treatment-Experienced, Naïve, Non responder, Cirrhosis, Null responder, Hepatitis C Virus, Relapser, Compensated Cirrhosis, Hepatitis C Genotype 1, Hepatitis C
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers Hitsman, Brian L Smoking Cessation, Major Depressive Disorder, Nicotine Dependence, Varenicline, Behavioral Activation Therapy, Cigarette Smoking
Efficacy, Pharmacokinetics, and Safety of GS-5806 in Hospitalized Adults With Respiratory Syncytial Virus (RSV) Infection Ison, Michael G
Association Between Bolus Rate and Duration of Adequate Labor Analgesia Lange, Elizabeth epidural bolus, pain management, labor analgesia
Open Label Safety and Efficacy Study of CO-1686 in Patients With T790M Positive NSCLC Who Have Failed One Previous EGFR-Directed TKI Mohindra, Nisha cancer, metastatic, locally advanced, lung, non-small cell lung cancer, NSCLC, epidermal growth factor receptor, EGFR, T790M, CO-1686, unresectable, recurrent, EGFR-directed therapy, irreversible EGFR inhibitor
Evaluation of the IBV® Valve for Emphysema to Improve Lung Function Kalhan, Ravi Bronchoscopic Lung Volume Reduction, Emphysema, Lung Diseases, coil, chronic bronchitis, shortness of breath, coughing
Radiographic Markers of Clinical Function in Cervical Spondylotic Myelopathy (CSM) Smith, Zachary MRI, spine, x-ray, control
Treatment of Pain Associated With Fibromyalgia Schnitzer, Thomas J pain, fibromyalgia
Lung-MAP: S1400 Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IIIB-IV Squamous Cell Lung Cancer Chae, Young Kwang
Comparison of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 12 Weeks in Adults With Chronic Genotype 2 HCV Infection Flamm, Steven L Hepatitis C, HCV, cirrhosis, Sofosbuvir, Sovaldi, SOF/GS-5816, GS-5816, GS-7977, liver, Treatment naive, Treatment Experience
Bay98-7196, Dose Finding / POC Study Robins, Jared
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-Administration of ABT-493 and ABT-530 With and Without RBV in Subjects With Chronic Hepatitis C Virus (HCV) Genotype 2 or Genotype 3 Infection Flamm, Steven L Chronic Hepatitis C, Hepatitis C Virus, Hepatitis C Genotype 3, Hepatitis C, Hepatitis C Genotype 2, interferon free, HCV
A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars Galiano, Robert D Hypertrophic scar, Cicatrix, Scar prevention, Scar revision
Effect of a Patient-Centered Decision App on TOLAC Grobman, William A Trial of labor after cesarean, Elective repeat cesarean delivery, Decision tool, Shared decision making
Rheumatoid Arthritis Synovial tissue Network Perlman, Harris R Synovitis, swollen joints, rheumatoid arthritis , RA
Assessment of Patient Positioning Ladner, Daniela P nerve compression
Rehabilitation Institute of Chicago Recruitment Registry Lieber, Richard
Dolutegravir Antiretroviral Strategy to Promote Improvement and Reduce Drug Exposure Taiwo, Babafemi O
A Phase 2a Study Evaluating the Safety and Efficacy of ABT-981 in Patients With Erosive Hand Osteoarthritis Schnitzer, Thomas J Osteoarthritis, Hand, Osteoarthritis, Musculoskeletal diseases, Joint diseases, Arthritis, Rheumatic diseases
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can be Removed by Surgery Agulnik, Mark
Peripheral Neuropathy Research Registry (PNRR) Ajroud-Driss, Senda Peripheral Neuropathy; Registry;
Alendronate to Prevent Loss of Bronchoprotection in Asthma Smith, Lewis J
Phase 3 Gene Therapy for Painful Diabetic Neuropathy Ajroud-Driss, Senda diabetic, neuropathy, shooting pain, burning pain, pins and needles pain, foot pain, ViroMed
Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics Patterson, Stavonnie
A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's Disease Brown Jr, Calvin R APREMILAST (CC-10004), CC-10004, Efficacy, Safety, Phase 3, Behçet's Disease
Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas Agulnik, Mark
Tolvaptan Phase 3 Efficacy and Safety Study in ADPKD Tuazon, Jennifer A ADPKD, Polycystic, kidney, ADPKD (Autosomal Dominant Polycystic Kidney Disease)
APOLLO Trial Clinical Investigation Plan - Transcatheter Mitral Valve Replacement with the Medtronic Intrepid™ TMVR System in patients with severe symptomatic mitral regurgitation McCarthy, Patrick M TMVR, TMV, Transcatheter, Mitral Valve, Mitral regurgitation, apollo
Efficacy and Safety Study as Monotherapy of SA237 to Treat NMO and NMOSD Cohen, Bruce Arnold
Efficacy and Safety Study of WTX101 in Adult Wilson Disease Patients Bega, Danny
A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC Chae, Young Kwang NSCLC, Non-Small Cell Lung Cancer, heregulin, ErbB3, docetaxel, pemetrexed
Low InTensity Exercise Intervention in PAD McDermott, Mary Douglas peripheral arterial disease, peripheral artery disease, PAD, exercise
Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides) Guitart, Joan CTCL, Mycosis fungoides, Hypericin, SGX301, MF
Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease Jain, Manu
Lithium Therapy: Understanding Mothers, Mood and Metabolism Clark, Crystal
RESOLVE II Clinical Evaluation of Safety and Efficacy of S8 Sinus Implant in Chronic Sinusitis Patients Tan, Bruce Kuang-Huay K
Comparative treatment analysis of patients with combined-type femoroacetabular impingement undergoing hip arthroscopy with either isolated acetabular osteoplasty or combined femoral and acetabular osteoplasty: A prospective study Stover, Michael
A Longitudinal Evaluation of Disease & Fibrosis Biomarkers in Different Groups of Heart Failure Patients to Enhance the Early Clinical Development of Compounds with Anti-fibrotic Activity in the Heart Shah, Sanjiv J heart failure, MRI, Acute decompensated heart failure , ADHF, Biomarkers, Anti-fibrotic Activity, Diastolic Dysfunction, CV002-004
Assessment of Femoral or Acetabular Chondral Defects in the Hip following Microfracture: Utilization of MR Imaging Omar, Imran M
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial Eskandari, Mark asymptomatic, carotid, stent, endarterectomy, embolic protection, medical management, hypertension, hyperlipidemia, cognition, risk factor control
To Evaluate the Impact of SBI on C. Difficile in Hospitalized UC Patients Hanauer, Stephen CDI, C. diff, Ulcerative Colitis, UC, IBD, Inflammatory Bowel Disease
The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience Miller, Emily
Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET) Stein, Brady Lee Polycythemia vera, Essential thrombocythemia, Hydroxyurea, PEGASYS, Pegylated Interferon Alfa-2a
Methylation Patterns of Committed, Stable Th17 Cells Predicts Asthma Severity: A Pilot Study Smith, Lewis J
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting Levitsky, Josh liver transplant, hepatitis C, Gilead, Communicable Diseases, Infection, Virus Diseases, Digestive System Diseases, Hepatitis, Viral, Human, Liver Diseases, RNA Virus Infections
Investigation of how nulliparous women make decisions regarding epidural use for labor analgesia Toledo, Paloma
Odontoid Fracture Study Treated With Pulsed Electromagnetic Fields Hsu, Wellington K PEMF, odontoid fracture, IDE, prospective
(xIRB) A Phase 2, Randomized, Double-Blind, Placebo-Controlled, 12- Month, Multiple-Dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602K in Patients with NASH (EMMINENCE™) Rinella, Mary Eugenia
Randomized, double-blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate (110 mg or 150 mg, oral b.i.d.) versus acetylsalicylic acid (100 mg oral q.d.) in patients with Embolic Stroke of Undetermined Source (RESPECT ESUS) Caprio, Fan
SANTE - Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy Ajroud-Driss, Senda Direct brain stimulation, SANTE
Phase 3 Study With Dual Release Ciprofloxacin for Inhalation in Non-CF Bronchiectasis Prickett, Michelle Lee Non Cystic Fibrosis Bronchiectasis, Pulmaquin, Ciprofloxacin, Pseudomonas aeruginosa
A5324: A Randomized, Double-Blinded, Placebo-Controlled Trial Comparing Antiretroviral Intensification with Maraviroc and Dolutegravir with No Intensification or Intensification with Dolutegravir Alone for the Treatment of Cognitive Impairment in HIV Taiwo, Babafemi O HIV infection, neurocognitive impairment, antiretroviral treatment, neuropsychologic testing
SPARC: Gene expression profiling in scleroderma to discover therapeutic targets and predict clinical course Varga, John scleroderma , inflammatory , fibrosis, systemic sclerosis , autoimmune , skin fibrosis , healthy control
Study of Dupilumab in Adult Patients With Active Eosinophilic Esophagitis (EoE) Hirano, Ikuo
OPsumit USers Registry Cuttica, Michael J pulmonary arterial hypertension, PAH
Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury Ganju, Aruna spine, injury, trauma, spine injury, cervical spine injury, cervical spine, stemcells transplantation
[Trial of device that is not approved or cleared by the U.S. FDA] Rinella, Mary Eugenia
Motor impairment related changes in muscles properties in chronic stroke Dewald, Julius P P
HIV acquisition among African-born US residents Taiwo, Babafemi O HIV, HIV diagnosis, African born
Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia Grobman, William A Preeclampsia, Preterm preeclampsia, Pregnancy
PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial Cuttica, Michael J
Biochronicity Grand Challenge: Human Time Stamp Development, Validation and Prediction Zee, Phyllis C traumatic brain injury
Etanercept and Methotrexate in Combination or as Monotherapy in Psoriatic Arthritis Ruderman, Eric M Psoriatic Arthritis, Arthritis, Psoriasis, Etanercept, Enbrel, Methotrexate, Minimal Disease Activity
Targeted Reinnervation as a Means to Treat Neuromas Associated With Major Limb Amputation Alghoul, Mohammed Assessment, Pain
Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002 Schnitzer, Thomas J Osteoarthritis, Pain, Fulranumab, JNJ-42160443, Monotherapy, Hip, Knee, Joint replacement surgery
Phase 3 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cirrhosis Flamm, Steven L Primary Biliary Cirrhosis, PBC, Cirrhosis, Liver
Association of Donor Age With Recipient Outcomes in Kidney Transplant Gallon, Lorenzo kidney, transplant
Trans-MAPP Symptom Patterns Study (SPS) Schaeffer, Anthony J pelvic pain, bladder pain
CLINICAL STUDY TO EVALUATE THE EFFECTIVENESS OF CUTIMED SILTEC B AND CUTIMED SORBACTDRESSINGS WITH JOBST ULCER CARE COMPRESSION FOR THE MANAGEMENT OF VENOUS LEG ULCERS Galiano, Robert D
Study of REGN475 in Patients With Pain Due to Osteoarthritis of the Knee or Hip Schnitzer, Thomas J
Study of Efficacy, Safety of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3001 Schnitzer, Thomas J Osteoarthritis, Pain, Fulranumab, JNJ-42160443, Adjunctive therapy, Opioid, Hip, Knee, Joint replacement surgery
SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE) Simuni, Tatyana PDD, Parkinson's Disease Dementia, patients taking a cholinesterase inhibitor.
Anxiety and COPD Evaluation Smith, Lewis J
Cabozantinib-S-Malate in Treating Patients With Recurrent or Progressive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Shahabi, Shohreh
Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer Shahabi, Shohreh
The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence Kenton, Kimberly mixed urinary incontinence, stress incontinence, urgency incontinence, urinary leakage, midurethral sling
PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial Goldstein, Debra
Open-Label Safety Study of ADS-5102 in PD Patients With LID Bega, Danny Levodopa Induced Dyskinesia, LID, Parkinsonism, Parkinson's Disease
Efficacy and Safety Study of ADS-5102 in PD Patients With Levodopa-Induced Dyskinesia Bega, Danny Levodopa-Induced Dyskinesia, LID, Parkinsonism, Parkinson's Disease
Preferences for Activating and Adhering to Physical Activity with Arthritis (PAAPAyA): Choice experiment Pinto, Daniel
The BASE Study: Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR) Isakova, Tamara
Sorafenib for Hepatopulmonary Syndrome Levitsky, Josh Randomized Controlled Trial, Clinical Trial, sorafenib, Hepatopulmonary Syndrome
Determinants of Coronary Microvascular Ischemia Shah, Sanjiv J
Telmisartan Plus Exercise to Improve Functioning in PAD McDermott, Mary Douglas peripheral artery disease, atherosclerosis, vascular disease, cardiovascular disease, telmisartan, exercise
Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma Pro, Barbara
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-493 and ABT-530 With and Without Ribavirin in Adults With Genotype 1 HCV Who Failed a Prior DAA Containing Therapy Flamm, Steven L HCV Genotype 1, Chronic Hepatitis C, HCV GT1, Interferon (IFN) free, Hepatitis C Genotype 1, Chronic HCV, Hepatitis C, HCV
ECOG-ACRIN 1131: A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy Vs. Capecitabine in Patients with Residual Triple-Negative Basal-Like Breast Cancer following Neoadjuvant Chemotherapy Flaum, Lisa
Advanced MRI and Ultrasound in the Characterization of Peripheral Nerve Disorders Kliot, Michel
A Prospective, Randomized, Comparative Effectiveness Study of a Single-Use, Negative Pressure Wound Therapy System (PICO) versus a Traditional Negative Pressure Wound Therapy System (tNPWT) in the Treatment of Lower Extremity Ulcers Galiano, Robert D
MEDI4736 and Tremelimumab in Treating Patients With Metastatic HER2 Negative Breast Cancer Cristofanilli, Massimo
Chronic Kidney Disease Research Biorepository Isakova, Tamara
Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation Levitsky, Josh Liver allograft recipient, Immunosuppression withdrawal, Calcineurin inhibitor (CNI) based immunosuppression, Living Donor (of the Respective Liver Transplant Recipient)
Iron Deficiency and FGF23 Regulation in Chronic Kidney Disease and Heart Failure Mehta, Rupal ckd, chf, iron sucrose, fgf23, iron deficiency
PACE - Patient-Centered Weight Loss Program for Knee Replacement Patients Pellegrini, Christine Knee replacement, weight loss, diet, physical activity
A Sacral Neuromodulation for Female Pelvic Floor Dysfunction Kielb, Stephanie J bowel symptoms, female pelvic pain, fecal incontinence, lower urinary tract symptoms, overactive bladder
SMART Weight Loss Management Spring, Bonnie Weight loss, Diet, Obesity, Physical Activity, Mobile Health
A Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediated Rejection in Patients With Kidney Transplant Friedewald, John J
Brighton: PNT2258 for Treatment of Patients With Richter's Transformation Kaplan, Jason PNT2258, Richter's Transformation, NHL, Non-Hodgkin's Lymphoma, Lymphoma, DLBCL, Diffuse Large B-cell Lymphoma, Lymphoma, Large B-cell, Diffuse, Lymphoma, Non-Hodgkin, Lymphoma, B-cell
CompuFlo® Assessment Study for the Epidural Space Verification Peralta, Feyce
A Prospective, Randomized, Single Center, Controlled Evaluation of the Effectiveness of OxyGenesysTM Topical Dissolved Oxygen Dressing in Accelerating the Healing of Split Thickness Skin Graft (STSG) Donor Sites Using the Northwestern University Abdominoplasty Scar Model Galiano, Robert D
JKB-121 for the Treatment of Nonalcoholic Steatohepatitis Rinella, Mary Eugenia NASH, Non-alcholic steatohepatitis, fatty liver disease
A Phase 3 Study to Examine the Efficacy, Safety and Tolerability of APL-130277 for the Acute Treatment of OFF Episodes in Patients With Parkinson's Disease Zadikoff, Cindy
Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients Taiwo, Babafemi O
Efficacy and Safety of BI 655066 in Patients With Severe Persistent Asthma. Rosenberg, Sharon Reifler lungs, severe asthma, shortness of breath, chest tightness, coughing, risankizumab, breathing, pulmonary
Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis Rinella, Mary Eugenia Liver Cirrhosis
AAD-PEPR: Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments Paller, Amy atopic dermatitis , eczema, itch, pediatric
Attention Bias: Testing a Potential Marker for the Diagnosis of Atypical Movement Disorders Bega, Danny Psychogenic Movement Disorders
A Prospective Study of Early Stage Breast Cancer Patients with Abnormal Myocardial Deformation treated with Anthracycline and/or Trastuzumab and Pertuzumab-based cancer therapy. Akhter, Nausheen Breast cancer, echocardiogram
NU 15B08: A Phase II Single Arm Study of Palbociclib in Patients with Metastatic HER2-positive Breast Cancer with Brain Metastasis Cristofanilli, Massimo
A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis Who Have an F508del-CFTR Mutation Jain, Manu
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061) Shulman, Lee P
Joint Complaints in Children with Harlequin Ichthyosis: A Study to Assess for Comorbidity Paller, Amy ichthyosis, harlequin ichthyosis, swelling, joint pain
Determination of ED90 of Intrathecal Lidocaine for Adequate Anesthesia for Elective Cervical Cerclage Surgery Toledo, Paloma Pain, Surgery, Pregnancy, Anesthesia
Skin Patch Sensors as a Substitute for Needle EMG Recordings to Detect Muscle Activity and Movement Dahdaleh, Nader
Standard of Care Therapy With or Without Stereotactic Radiosurgery and/or Surgery in Treating Patients With Limited Metastatic Breast Cancer Strauss, Jonathan B
Defining the Skin and Blood Biomarkers of Ichthyosis Paller, Amy ichthyosis, pediatric
Safety and Efficacy of GS-5745 in Participants With Moderately to Severely Active Crohn's Disease Hanauer, Stephen
Genomic Medicine at Northwestern: Discovery and Implementation in the eMERGE Network Smith, Maureen E
Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients Using Levodopa Zadikoff, Cindy Motor fluctuations, Off time, On time, Dyskinesia
Defining The Skin and Blood Biomarkers of Pediatric Atopic Dermatitis Paller, Amy atopic dermatitis, eczema, pediatric
Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones Nadler, Robert B Kidney Stones, Nephrolithiasis, Urine Oxalate, Hyperoxaluria, Enteric Hyperoxaluria, Idiopathic Hyperoxaluria, Urological Diseases, Kidney Diseases, Dietary Oxalate
Healthy Hearts in the Heartland Kho, Abel N Preventive measures, Quality Improvement
Influenza Vaccine Responses as a Means of Assessing Immune Competence in Chimeric Kidney/Stem Cell Transplant Recipients Leventhal, Joseph R
A Randomised, Double-Blind, Parallel Group, Placebo-Controlled Multi-Centre Phase III Study to Assess the Efficacy and Safety of Olaparib Versus Placebo as Adjuvant Treatment in Patients with Germline BRCA1/2 Mutations and High Risk HER2 Negative Primary Breast Cancer Who Have Completed Definitive Local Treatment and Neoadjuvant or Adjuvant Chemotherapy Cristofanilli, Massimo
High Resolution and Functional MRI Assessment of Intracranial Atherosclerotic Plaque Ansari, Sameer Ahmad
Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy Flamm, Steven L Chronic Hepatitis C Infection
Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014) Wunderink, Richard G
Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (NHL) Gordon, Leo I I JCAR017, chimeric antigen receptor, non-Hodgkin lymphoma, CAR, CAR T cells, autologous T cell therapy, cell therapy, NHL
Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year Sufit, Robert L fast skeletal troponin activator, tirasemtiv, CK-2017357, double-blind, randomized, placebo-controlled
Prospective trial evaluating the long-term outcomes associated with the use of MTF allograft cartilage in cosmetic and reconstructive rhinoplasty procedures Galiano, Robert D
Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy Agulnik, Mark
NU 16U05: A Randomized Phase II Trial of Abiraterone, Olaparib, or Abiraterone + Olaparib in Patients with Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects Hussain, Maha
Randomized Phase II Study of Cisplatin and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas. Benson III, Al B
Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease Molitch, Mark E Type 2 Diabetes, Kidney diseases
Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities Eskandari, Mark Rivaroxaban, Xarelto, Aspirin, Acetylic salicylic acid, Anticoagulant, Peripheral artery disease, Peripheral arterial disease, Revascularization, Acute limb ischemia, Amputation, Cardiovascular events
Healthy Control Esophageal Registry and Biorepository Carlson, Dustin healthy control , scleroderma , GERD, scleroderma esophagus
Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest) Peters, Anju Tripathi
Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 in Adults With Chronic HCV Infection Who Have Previously Received Treatment With Direct-Acting Antiviral Therapy Flamm, Steven L Chronic Hepatitis C Infection
An Open-Label, Pilot Pharmacokinetic Study of INCB018424 Phosphate Cream in Pediatric Subjects With Atopic Dermatitis Paller, Amy Atopic dermatitis, eczema , itchy , scaling, scratching
NU JH17U01: Overcoming drug resistance in metastatic castration-resistant prostate cancer with novel combination of TGF-β receptor inhibitor LY2157299 and enzalutamide: a randomized multi-site phase II study Morgans, Alicia
An Open-Label, Multicenter and Open Enrollment Model, Postmarketing, Milk-Only Lactation Study to Assess Concentration of Vedolizumab in Breast Milk of Lactating Women With Active Ulcerative Colitis or Crohn’s Disease Who Are Receiving Vedolizumab Therapeutically Stein, Adam Lactation, Lactating Women, Vedolizumab, Colitis Ulcerative, Crohn Disease, Crohn's, Inflammatory Bowel Diseases, Gastrointestinal Diseases, Digestive System Diseases, Colonic Diseases, Intestinal Diseases
Study of N91115 in Patients With CF Homozygous for the F508del-CFTR Mutation Jain, Manu Cystic Fibrosis, N91115
Modeling Neuroscience for Enhancing Memory Operations through Non-Invasive Channels (MNEMONIC) Zee, Phyllis C
A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Subjects With Genotype 1 Infection Flamm, Steven L Chronic Hepatitis C, Hepatitis C Genotype 1 (GT1), IFN free, HCV GT1, Hepatitis C, Ribavirin Free, Non-cirrhotic, Interferon (IFN) Free, HCV, Hepatitis C virus, DAA, RBV Free, Without cirrhosis
Comparing the Efficacy and Safety of High-Titer Versus Low-Titer Anti-Influenza Immune Plasma for the Treatment of Severe Influenza A Ison, Michael G Anti-Influenza Immune Plasma
Walking Green: The Effects of Walking in Forested and Urban Areas on Health and Well-being Horton, Teresa Walking, Evanston
NU 16L04: Parallel proof of concept phase 2 study of nivolumab and metformin combination treatment in advanced non-small cell lung cancer with and without prior treatment with PD-1/PD-L1 inhibitors Chae, Young Kwang
Pravastatin for Prevention of Preeclampsia Wisner, Katherine preeclampsia, pravastatin, Pravachol®, statin, high-risk pregnancy, safety, fetal morbidity and mortality, maternal morbidity and mortality, neonatal mortality, premature delivery, preemie
Phase II study of nivolumab and ipilimumab for treatment of advanced adenoid cystic carcinoma and non-adenoid cystic carcinoma Matsangou, Maria
Clinical Research Consortium for the Study of Cerebellar Ataxia (CRC-SCA) to Study Natural History and Genetic Modifiers in Spinocerebellar Ataxia (SCA) Opal, Puneet SCA Database Study , Spinocerebellar Ataxia
Vagus Nerve Stimulation Titration Protocol to Improve Tolerance and Accelerate Adaptation Macken, Micheal P Vagus Nerve Stimulation, ASCEND, VNS Titration to Improve Tolerance and Accelerate Adaptation
A PHASE I STUDY OF NEURAL STEM CELL BASED VIROTHERAPY IN COMBINATION WITH STANDARD RADIATION AND CHEMOTHERAPY FOR MALIGNANT GLIOMA Lesniak, Maciej malignant glioma, virotherapy, stem cells, newly diagnosed
(CIRB) A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (NASH) Rinella, Mary Eugenia NASH, CIRRHOSIS, FATTY LIVER DISEASE
Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease Kalhan, Ravi Smoking, flare-ups, oxygen, shortness of breath, emphysema, chronic bronchitis
Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment Rinella, Mary Eugenia Non Alcoholic Steatohepatitis, fatty liver disease, NASH, liver fibrosis
Safety and Efficacy of SOF/VEL/GS-9857 FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor Flamm, Steven L Chronic
Safety and Efficacy of SOF/VEL/GS-9857 FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis Flamm, Steven L Chronic
A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO AND ACTIVE-CONTROLLED, MULTICENTER, PARALLEL-GROUP STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF TANEZUMAB IN ADULT SUBJECTS WITH CHRONIC LOW BACK PAIN Walega, David R chronic pain, low back pain
A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection Ison, Michael G Influenza A virus, JNJ-63623872, Oseltamivir
A Phase ll Study of IMM-124E for Patients With Non-alcoholic Steatohepatitis Rinella, Mary Eugenia NASH , Non-alcoholic steatohepatitis, fatty liver disease, Non-alcoholic Steatohepatitis, nonalcoholic steatohepatitis
Liver Test Study of Using JKB-122 in AIH Patients Flamm, Steven L AIH, JKB-122, autoimmune, hepatitis
Dilated Cardiomyopathy (DCM) Research Project Wilcox, Jane Elizabeth DCM, Dilated Cardiomyopathy
(CIRB) A Phase 2, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 Weeks in Subjects with Chronic HCV Infection and Child-Pugh-Turcotte Class C Cirrhosis Flamm, Steven L Hepatitis C
A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain Schnitzer, Thomas J
METIS: Pivotal, open-label, randomized study of radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 brain metastases from non-small cell lung cancer (NSCLC) Kumthekar, Priya
A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation Jain, Manu
Study of OTO-104 in Subjects With Unilateral Meniere's Disease Micco, Alan G Meniere's Disease, Vertigo
Corrona Psoriasis Registry Amin, Ahmad psoriasis
Gene Expression and Biomarker Profiling of Keloid Skin Sub-Study: A Pilot Trial of Keloid Genomic Profiling Using RNAseq Kundu, Roopal Vashi keloid
BTCRC GYN15-013: Phase II Study of Pembrolizumab in Combination with Carboplatin and Paclitaxel for Advanced or Recurrent Endometrial Adenocarcinoma Matei, Daniela
Immunogenicity of Nonavalent HPV Vaccine Administered Prior To Living Donor Renal Transplantation in Adult Women: A Prospective, Single-Arm, Multi-Center Clinical Trial Ison, Michael G
Assessment of pathologic complete response using simultaneous dynamic contrast enhanced breast MRI (DCE-MRI) and FDG-PET in the HER2-enriched breast cancer population. Bhole, Sonya
An International, Multicenter, Randomized, Double-Blind, Parallel-Group Phase 2 Study Evaluating the Safety and Efficacy of Diacerein 1% Ointment Topical Formulation in Subjects with Epidermolysis Bullosa Simplex (EBS). Paller, Amy epidermolysis bullosa simplex, EBS
A phase 3 randomized, open-label (sponsor-blind), activecontrolled, parallel-group, multi-center, event driven study in non-dialysis subjects with anemia associated with chronic kidney disease to evaluate the safety and efficacy of daprodustat compared to darbepoetin alfa. Ghossein, Cybele Anemia, chronic kidney disease, non-dialysis
COAST-1: Clinical Knee Osteoarthritis Symptom Treatment 1 Study A Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of AXS-02 (Disodium Zoledronate Tetrahydrate) Administered Orally to Subjects with Knee Osteoarthritis Associated with Bone Marrow Lesions. Schnitzer, Thomas J knee pain, knee, pain, osteoarthritis, knee osteoarthritis
Effect of L-dopa In Subacute Back Pain Population Apkarian, Apkar Subacute, Back, Pain, Brain, MRI
Evaluating the Circadian Response to Light in Delayed Sleep-Wake Phase Disorder Abbott, Sabra circadian rhythm, sleep
Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Safety, Tolerability, and Efficacy of Ixekizumab in Patients from 6 to Less than 18 Years of Age with Moderate-to-Severe Plaque Psoriasis Paller, Amy psoriasis, plaque psoriasis
DRUG CA209-816: Randomized, Open-Label, Phase 3 Trial of Nivolumab plus Ipilimumab or Nivolumab plus Platinum-doublet Chemotherapy versus Platinum-Doublet Chemotherapy in Early Stage NSCLC Mohindra, Nisha
Comparison of the efficacy between Cryolipolysis versus ATX-101 (Deoxycholic acid) for the treatment of upper back fat: a prospective randomized controlled pilot study Alam, Murad fat reduction, cryolipolysis, kybella, back fat, cosmetic dermatology
NU UW16B13: A Phase II Study of Neratinib Alone and in Combination with Fulvestrant in Metastatic HER2 Non-amplified but HER2 Mutant Breast Cancer Cristofanilli, Massimo
(xIRB) NCI CIRB - NRG LU002: Comparing Standard Treatment Alone to Radiation Therapy With Standard Treatment for Patients With Limited Metastatic Non-Small Cell Lung Cancer Kruser, Timothy
(xIRB) A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Filgotinib and GS-9876 in Female Subjects with Moderately-to-Severely Active Cutaneous Lupus Erythematosus (CLE) Laumann, Anne E cutaneous lupus erythematosus, rash, lesions
Comparison of Oral Octreotide Capsules to Injectable Somatostatin Analogs in Acromegaly Molitch, Mark E Octreotide Capsules, Acromegaly, Somatostatin, Mpowered, OOC-ACM-302
Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients Jain, Manu cystic fibrosis, ΔF508, RNA therapies, antisense oligonucleotide, CFTR, F508del, CF, RNA therapy
Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass Pham, Duc Thinh coronary artery bypass grafting, CABG, mitral valve, LCOS, low cardiac output syndrome, levosimendan
Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Goldstein, Debra Uveitis, UME, Posterior Uveitis, Anterior Uveitis, Intermediate Uveitis, Panuveitis, Non-infectious Uveitis, Triamcinolone, Choroid, Choroidal Injection, Suprachoroidal, Microneedle, Microinjection
(xIRB NCI-CIRB) SWOG 1512: A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unsectable Desmoplastic Melanoma (DM) Chandra, Sunandana
MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC) Chae, Young Kwang NSCLC
A Phase 2b, Open-Label Study of 200 mg or 400 mg Sofosbuvir+RBV for 24 Weeks in Genotype 1 or 3 and Ledipasvir/Sofosbuvir (LDV/SOF) Fixed-Dose Combination (FDC) Tablet for 12 weeks in Genotype 1 or 4 HCV-Infected Subjects with Renal Insufficiency Flamm, Steven L Hepatitis C, Renal Insufficiency, Harvoni
Establishing a methodology to assay CO in peripheral human blood Wisner, Katherine
Molecular Biomarkers of Improvement for Patients with Systemic Sclerosis Hinchcliff, Monique E systemic sclerosis, scleroderma, genetics, gene expression, healthy controls, biomarkers
Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease Ansari, Sameer Ahmad Intracranial Atherosclerotic Disease, Stroke, Transient Ischemic Attack, Imaging
A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor Peaceman, Alan M Spontaneous Preterm Labor, GSK221149, Retosiban
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation Jain, Manu
Study to Evaluate Multiple Doses in Patients With Nasal Polyposis Peters, Anju Tripathi
[Trial of device that is not approved or cleared by the U.S. FDA] Wolfe, Lisa F
NCI 2015-06-03 Statin Therapy to Reduce Disease Progression from Liver Cirrhosis to Cancer Kulik, Laura M liver, cirrhosis, statin, HCC, Hepatocellular Carcinoma, prevention, simvastatin
DRUG CO39722: A PHASE III, OPEN-LABEL, MULTICENTER, TWO-ARM, RANDOMIZED STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF COBIMETINIB PLUS ATEZOLIZUMAB VERSUS PEMBROLIZUMAB IN PATIENTS WITH PREVIOUSLY UNTREATED ADVANCED BRAFV600 WILD-TYPE MELANOMA. Chandra, Sunandana
A Phase II Randomized Study of Nivolumab (NSC-748726) with Ipilimumab (NSC-732442) OR Ipilimumab Alone in Advanced Melanoma Patients Refractory to an Anti-PD-1 or Anti-PD-L1 Agent" Sosman, Jeffrey
Study of Gelesis100 on Body Weight in Overweight and Obese Subjects With and Without Type 2 Diabetes Kushner, Robert F
Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers Taiwo, Babafemi O
Efatutazone With Paclitaxel Versus Paclitaxel Alone in Treating Patients With Advanced Anaplastic Thyroid Cancer Matsangou, Maria
13C-Methacetin Breath Test for the Prediction of Outcome in Acute Liver Injury or Acute Liver Failure Ganger, Daniel R Acute liver failure
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer Gradishar, William J
A Double Blind, Randomized, Vehicle Controlled, Crossover Study to Evaluate the Safety and Efficacy of Topical Naloxone Hydrochloride Lotion 0.5% for the Relief of Pruritus in Patients with the Mycosis Fungoides (MF) or Sézary Syndrome (SS) Forms of Cutaneous T-Cell Lymphoma (CTCL) Guitart, Joan mycosis fungoides, MF, Cutaneous T Cell Lymphoma, CTCL , Naloxone
A phase III randomized open-label multi-center study of ruxolitinib vs. best available therapy in patients with corticosteroid-refractory chronic graft vs host disease after allogeneic stem cell transplantation (REACH 3) Choi, Jennifer graft versus host disease, GVHD, stem cell transplant
A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate the Safety and Efficacy of Avacopan (CCX168) in Patients with C3 Glomerulopathy Ghossein, Cybele c3 glomerulopathy, c3gn, dense deposit disease, ddd, c3 glomerulonephritis , complement, c3g
Effects of Pubic Hair Grooming on Urinary and Vaginal Microbiome Mueller, Margaret
Prostatic Artery Embolization (PAE) for Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) Salem, Riad
LURN: Qualitative Assessment of Lower Urinary Tract Dysfunction Study Protocol 2: Recall Study Cella, David urgency, incontinence, nocturia
Phase Ib, open label, combination study of nintedanib with 5- azacitidine in acute myeloid leukemia characterized by HOX gene overexpression, that are not candidates of intensive chemotherapy Altman, Jessica K
Clinical Trial Readiness for SCA1 and SCA3 Opal, Puneet Ataxia, Genetics, SCA1, SCA 3
A randomized, double-blind, multi-centre, placebo-controlled, parallel-arm phase 2 trial to assess safety, efficacy and pharmacokinetics of CD11301 0.03% and 0.06% gel in the treatment of Cutaneous T-Cell Lymphoma (CTCL), stages IA, IB and IIA (Protocol #RD.03.SPR.104003) Guitart, Joan CTCL , Cutaneous T Cell Lymphoma
Vasculitis Clinical Research Consortium (VCRC) Genetic Repository One Time DNA Protocol Archer, Amy vasculitis, genetics, DNA
Neural pathways underlying discrimination and generalization in associative learning Kahnt, Thorsten
A Study To Confirm Efficacy and Safety of Terlipressin in HRS Type 1 Ganger, Daniel R Hepatorenal Syndrome Type 1
A Prospective Review of Excimer Laser-Assisted IVC Filter Removal Lewandowski, Robert J IVC filter removal, IVC filter
Tralokinumab in combination with topical corticosteroids for moderate-to-severe atopic dermatitis Silverberg, Jonathan eczema, atopic dermatits, itch, pruritus
(CIRB) A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Elafibranor in Patients with Nonalcoholic Steatohepatitis (NASH) and fibrosis Rinella, Mary Eugenia NASH and Fibrosis
A Study Looking at Targeted Therapy According to Tumor Markers for People With Meningiomas Kumthekar, Priya
A Randomized, Multicenter, Double-Blind, Parallel, Active-Control Study of the Effects of Sparsentan, A Dual Endothelin Receptor and Angiotensin Receptor Blocker, on Renal Outcomes in Patients with Primary Focal Segmental Glomerulosclerosis Ghossein, Cybele focal segmental glomerulosclerosis, fsgs
Pulmonary Fibrosis Foundation Patient Registry Bhorade, Sangeeta
A STUDY OF THE EFFICACY AND SAFETY OF BARDOXOLONE METHYL IN PATIENTS WITH CONNECTIVE TISSUE DISEASE-ASSOCIATED PULMONARY ARTERIAL HYPERTENSION VERSION 1.0 – 27 JAN 2016 Cuttica, Michael J Pulmonary Hypertension Pulmonary Arterial Hypertension Connective Tissue Disease-Associated Pulmonary Arterial Hypertension Bardoxolone methyl
A Multicenter, Randomized, Double-Blind, Placebo- Controlled Trial of Emricasan (IDN-6556), an Oral Caspase Inhibitor, in Subjects with Non-alcoholic Steatohepatitis (NASH) Fibrosis Rinella, Mary Eugenia NASH, fatty liver disease
AHA Strategically Focused Research Network: mHealth Intervention to Preserve and Promote Ideal Cardiovascular Health-Study 2 Spring, Bonnie College student, cardiovascular health
Northwestern Scleroderma Twins Registry and Biorepository Varga, John twins, scleroderma, systemic sclerosis, genetics, epigenetics, genes
Multidisciplinary Treatment for Obstructive Sleep Apnea and Insomnia Ong, Jason C OSA, Obstructive sleep apnea, insomnia, CBT, CBT-I, CPAP, Sleep study, sleep disorders
(CIRB) A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-0976 in Subjects with Nonalcoholic Steatohepatitis Rinella, Mary Eugenia fatty liver disease
ACTG A5354: Effect of Antiretroviral Treatment Initiated During Acute HIV-1 Infection on Measures of HIV-1 Persistence and on HIV-1-Specific Immune Responses Taiwo, Babafemi O acute infection , HIV infection, antiretroviral treatment
A Multicenter, Open-label, Single-Arm Study to Evaluate the Contraceptive Efficacy and Safety of a Combined Oral Contraceptive Containing 15 mg Estetrol and 3 mg Drospirenone Shulman, Lee P Contraceptive, birth control, women
Alzheimer’s Disease Neuroimaging Initiative 3 Rogalski, Emily Joy
SMART: A prospective, multi-center registry assessing the embolization of neurovascular lesions using the Penumbra SMART COIL® System Hurley, Michael
Chicago Adolescent Longitudinal Study Reilly, James Young Adult, Adult, MRI, Brain imaging, Bipolar, Bipolar Type 1, Bipolar Type 2, Schizophrenia, Schizoaffective, Depression, Imaging
Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta Hoel, Andrew Aortic Aneurysm, Aortic Dissection, Intramural Hematoma, Aortic Disease, Aortic Injury
Study in Recipients of Renal Transplant Allograft to Evaluate the Impact of Two Immunosuppressive Regimens Gallon, Lorenzo transplant, kidney, renal disease
Repetitive Transcranial Magnetic Stimulation in Breast Cancer Patients With Depression and Anxiety Dokucu, Mehmet E repetitive Transcranial Magnetic Stimulation, Breast Cancer Survivor, Depression, Anxiety, rTMS
Mild Cognitive Impairment in Breast Cancer Patients Wang, Lei breast cancer, invasive ductal carcinoma, DCIS, ductal carcinoma in situ, cognitive impairment, adjuvant therapy, hormone therapy, hormonal therapy, chemotherapy, chemo brain, MRI, brain, cognition
Mobile Monitoring for Long Term Behavioral Data Collection in Bipolar Disorder Goulding, Evan Mobile, Cell Phone, Bipolar, Bipolar Type 1, Bipolar Type 2, Relapse, Mobile Applications, Apps
Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults Taiwo, Babafemi O HIV, Cardiovascular Disease, Myocardial Infarction, Inflammation, Statin, heart disease
Effect of Magnesium Threonate (MgT) on Cognitive Enhancement in Schizophrenia Meltzer, Herbert Schizophrenia, Schizoaffective disorder, Cognition, Magnesium, Imaging, Negative symptoms, Clinical Trial, Memory, Investigational Drug, Medication
NEUROLOGICAL MECHANISMS OF TREATMENT PROJECT (NMT): AN EXAMINATION OF THE NEUROLOGICAL EFFECTS OF COGNITIVE BEHAVIORAL THERAPY ON ADOLESCENTS WITH DEPRESSION Breiter, Hans Depression, Young adult, Adolescent, Therapy, Cognitive Behavioral Therapy, CBT, Cognitive Therapy, MDD, Major Depressive Disorder
Testing the Ability of JNJ-18038683 to Improve Cognition and Reduce Depressive Symptoms in Stable Bipolar Patients Meltzer, Herbert Bipolar, Depression, Cognition, Cognitive, Mood, Memory, Investigational Drug, Mania, Hypomania, Bipolar Type 1, Bipolar Type 2, Clinical Trial
Optimizing Medication Management for Mothers with Depression (OPTI-MOM) Wisner, Katherine pregnancy, depression, psychiatry, psychology, mental health, postpartum, ssri, anti-depressant, antidepressant, prozac, zolof, celexa, lexapro, pregnant
Comparison of a Long-acting Injectable Antipsychotic vs Clinician's Choice Early in Treatment to Break the Cycle of Relapse in Early Phase Schizophrenics Rado, Jeffrey First Episode, Recent Onset, Schizophrenia, Cognition, Magnesium, Imaging, Clinical Trial, Memory, Investigational Drug, Medication, MRI
Culturally Adapted Cognitive Behavioral Stress and Self-Management (C-CBSM) Intervention for Prostate Cancer Miller, Greg Prostate Cancer, Relaxation Techniques, Hispanic male, Spanish, Stress Management, hispanic, latino, hombres, espanol, cancer de prostata
Early Feasibility Study of the CardiAQ-Edwards™ Transcatheter Mitral Valve (TMV) System For the Treatment of Moderate to Severe Mitral Regurgitation Davidson, Charles J mitral valve regurgitation, MR, TMVI, TMVR , Center for Heart Valve Disease
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Subjects with Nonalcoholic Steatohepatitis (NASH) Rinella, Mary Eugenia NASH
A Randomized Trial of Pessary in Singleton Pregnancies with a Short Cervix (TOPS) Grobman, William A preterm delivery, arabin pessary, short cervix
Northwestern University The Department of Psychiatry and Behavioral Sciences, Clinical Research Program (NU CRP) Recruitment Pipeline Goldman, Morris B Schizophrenia, Schizoaffective, Depression, Anxiety, Bipolar, Bipolar Type 1, Bipolar Type 2, Mania, Hypomania, Major Depressive Disorder, Mood, Cognition, Research Study, Adult, Adolescent, Children, Alzheimer's disease, Clinical Trial, Non Clinical Trial, Therapy, Investigational Drug, Post Traumatic Stress Disorder
Open-label safety trial of intravenous neridronic acid in subjects with complex regional pain syndrome (CRPS) Schnitzer, Thomas J CRPS, neridronic, acid, complex regional pain syndrome, complex, regional, pain, syndrome, reflex sympathetic dystrophy, RSD
Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Rich MD, Stuart percutaneous, tricuspid , tricuspid regurgitation, valve, Center for Heart Valve Disease, SCOUT, Chronic functional tricuspid regurgitation, Valve Annuloplasty, PTVAS, Heart Failure, tricuspid valve repair, IDE
The Effect of KNO3 Compared to KCl on Oxygen Uptake in Heart Failure with Preserved Ejection Fraction Shah, Sanjiv J heart failure, HFpEF, preserved ejection fraction, exercise, KNO3CK-OUT
Impact of Hemodynamic Ramp Test-Guided HVAD RPM and Medication Adjustments on Exercise Tolerance and Quality of Life: A Multicenter Study Rich, Jonathan LVAD, Center for Heart Failure, Heart Failure, left ventricular assist device , Echocardiography, Ramp-It-Up, Ramp Test
(xIRB) NCI CIRB: SWOG 1612: A RANDOMIZED PHASE II/III TRIAL OF “NOVEL THERAPEUTICS” VERSUS AZACITIDINE IN NEWLY DIAGNOSED PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML) OR HIGH-RISK MYELODYSPLASTIC SYNDROME (MDS), AGE 60 OR OLDER (LEAP: LESS-INTENSE AML PLATFORM TRIAL) Frankfurt, Olga
Clinical Database of male Testosterone Deficiency at Northwestern University Brannigan, Robert E Testosterone deficiency, infertility
Protocol ATI001-102 Expansion Substudy: Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects with Recurrent or Progressive Glioblastoma Lesniak, Maciej glioblastoma, brain tumor, viral vector
A Randomized Trial of Induction Versus Expectant Management Grobman, William A First time moms, induction, expectant management, group assignment, singleton pregnancy
Is a Chance to Cut a Chance to Heal? A Pilot Study to Determine the Role of Submucosal Fibroids in Endometrial Gene Expression and Function Bernardi Wendeln, Lia fibroids, uterus, menstrual bleeding, miscarriage
Prevalence of aneuploidy in ectopic pregnancies Feinberg, Eve ectopic pregnancy, genetic testing, aneuploidy, infertility, fertility, pathology
Multi-Center Clinical Evaluation of the Access AMH Assay to Measure AMH as an Aid in the Prediction of Poor Ovarian Response to Controlled Ovarian Stimulation Pavone, MaryEllen Ellen AMH, anti-Mullerian hormone, IVF, ovarian reserve, fertility, infertility, in vitro fertilization
RELIEF: A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain (A7007) Rosenow, Joshua M neurostimulation, chronic pain
Precision Retrospective Outcomes (PRO) Rosenow, Joshua M neurostimulation, spinal cord stimulation
(xIRB NCI CIRB) ALLIANCE A041501: A PHASE III TRIAL TO EVALUATE THE EFFICACY OF THE ADDITION OF INOTUZUMAB OZOGAMICIN (A CONJUGATED ANTI-CD22 MONOCLONAL ANTIBODY) TO FRONTLINE THERAPY IN YOUNG ADULTS (AGES 18-39 YEARS) WITH NEWLY DIAGNOSED PRECURSOR B-CELL ALL Dinner, Shira
A Randomized, Double-Blinded, Placebo-Controlled, Multicenter Pilot Study of the SPRINT Peripheral Nerve Stimulation (PNS) System for the Treatment of Post-Amputation Pain Rosenow, Joshua M Amputee, peripheral nerve stimulation
rTMS: A Treatment to Restore Function After Severe TBI Pape, Theresa L Bender L Transcranial Magnetic Stimulation, traumatic brain injury
Geometric Surrogates for Clinical Management of Abdominal Aortic Aneurysms Eskandari, Mark AAA, Abdominal Aortic Aneursym, AAA Repair, Vascular Surgery, AAA Surveilence
Chemokine mechanisms in chronic pelvic pain Thumbikat, Praveen Pelvic pain, genitourinary pain , prostatitis
MAST CELLS IN MALE CHRONIC PELVIC PAIN AND LOWER URINARY TRACT DYSFUNCTION Thumbikat, Praveen chronic prostatitis, chronic pelvic pain syndrome, prostatitis, male pelvic pain
STOP Persistent AF Lin, Albert Electrophysiology, Cryoablation, IDE, Atrial Fibrillation, Cryoablation Catheter, Paroxsmal AF, Persistent AF, Cardiac Cryoablation Catheter
A Randomized, Double-Blind, Placebo-Controlled Phase 4 Study to Evaluate the Efficacy and Safety of Entyvio (Vedolizumab IV) in the Treatment of Chronic Pouchitis (EARNEST) Baidoo, Leonard Drug Therapy , Pouchitis , Vedolizumab , Colitis, ulcerative , ulcerative colitis , Gastrointestinal Diseases, Inflammatory Bowel Diseases, Colonic Diseases, Intestinal Diseases
A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effectiveness of a Nutritional Intervention in Improving the Intestinal Mucosal Health Status in Subjects with Crohn’s Disease (CD) Receiving Anti-TNF Therapy (PIONEER-CD) Hanauer, Stephen Crohn's Disease , Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases, mucosal healing, inflammatory bowel disease, Medical Food , Crohn Disease
Improve PAD PERformance with METformin: The PERMET Trial McDermott, Mary Douglas peripheral artery diease, peripheral arterial disease, leg pain , walking difficulty
A Randomized Double-Blind Phase 4 Study to Evaluate the Safety and Proportion of Subjects With Fistula Healing in 2 Dose Regimens of Entyvio (Vedolizumab IV) in the Treatment of Fistulizing Crohn’s Disease (ENTERPRISE) Baidoo, Leonard Crohn Disease , Crohn's Disease , Inflammatory Bowel Diseases , Gastroenteritis, Gastrointestinal Diseases , Digestive System Diseases, Intestinal Diseases, Vedolizumab, Gastrointestinal Agents
HOme-based moNitORed exercise for PAD McDermott, Mary Douglas peripheral artery disease; , PAD, leg pain, walking difficulty
The Safety and Effectiveness of the VaricElla zosteR VaccinE (VERVE) in Anti-TNF Users Hanauer, Stephen Vaccines , crohn's disease , Arthritis , Inflammatory Bowel Diseases , Gastroenteritis , Gastrointestinal Diseases , Digestive System Diseases , Intestinal Diseases
REVAMP Study (REmodeling the Left Ventricle with Atrial Modulated Pacing) Shah, Sanjiv J HFpEF, LV Chamber, heart failure, preserved ejection fraction, pacemaker, hypertrophy, REVAMP
Microbiologic Determinants of Self-perceived Bladder Health Mueller, Margaret
A Phase 2, Multicenter, Randomized, Double-Blind, Parallel, Placebo-Controlled Study of LY3074828 in Subjects with Moderate to Severe Ulcerative Colitis Hanauer, Stephen IL-23 antibody , Colitis, Ulcerative, ulcerative colitis, Gastroenteritis , Gastrointestinal Diseases, Digestive System Diseases, Colonic Diseases, Intestinal Diseases, Pathologic Processes, Inflammatory Bowel Diseases
Interventional, randomized, double-blind, active-controlled study of the efficacy of Lu AF35700 in patients with early-in-disease or late-in-disease treatment-resistant schizophrenia Meltzer, Herbert schizophrenia , psychosis , clinical trial , medication , hallucinations , delusions
Genetics in Retinal Diseases Project Lyon, A Thayer
Institution-wide Registry of Klinefelter Syndrome Patients Brannigan, Robert E Klinefelter Syndrome
Next-Generation sequencing of cell-free circulating tumor DNA in locally invasive bladder cancer Meeks, Joshua J bladder cancer
Spina Bifida Database of Northwestern University Kielb, Stephanie J spina bifida
Clinical Database of Peyronie’s Disease at Northwestern University Bennett Jr, Nelson Peyronie's Disease
A Single-Center Pilot Study of the Role of Transurethral Ultrasound in Staging Bladder Cancer in Patients Scheduled to Undergo Transurethral Resection of Bladder Tumor Kundu, Shilajit D bladder cancer
The Molecular Markers of Bladder Cancer Meeks, Joshua J bladder cancer
Clinical Database of Nephrectomy at Northwestern University Nadler, Robert B kidney cancer
Partial Wave Spectroscopy for Urine Cytology Analysis Meeks, Joshua J bladder cancer
LiveWell: A Mobile Intervention for Bipolar Disorder Goulding, Evan Bipolar Type 1, Mania, Depression, Bipolar, Mood disorders, Mental health, Lithium, Depakote, Abilify, Latuda, Zyprexa, Seroquel, Smartphone
A Prospective, Double-masked, Placebo Controlled Comparison of Topical 0.15% Ganciclovir Gel (Zirgan®) Versus 0.3% Hypromellose Gel (Genteal Gel®; Placebo) for the Treatment of Herpes Zoster Keratitis While on Oral Anti-viral Treatment Feder, Robert S herpes zoster ophthalmicus
INtervention Study In OverweiGHT Patients with COPD (INSIGHT COPD) Kalhan, Ravi COPD, overweight, healthy lifestyle
Clinical Database of Percutaneous Nephrolithotomy (PCNL) Nadler, Robert B kidney stones
Clinical Database of Prostate Cancer at Northwestern University Schaeffer, Edward Prostate cancer
PET/MRI using [18F]-DCFPyL for the Staging of Newly Diagnosed Prostate Cancer Schaeffer, Edward Prostate Cancer
Synthetic Lipoprotein Nanoparticles as Biosensors for Rapid Ex Vivo Assessment of Lecithin: Cholesterol Acyltransferase Activity Thaxton, Colby S
Isolation of peripheral blood mononuclear cells to develop novel therapeutics for cancer and autoimmune diseases Thaxton, Colby S
Risk Stratification in Older Persons with Acute Myocardial Infarction: SILVER-AMI Mikati, Issam A Center for Coronary Disease, Heart Disease, heart attack, MI
MOMENTUM 3 IDE Clinical Study Protocol Anderson, Allen Heart Failure, Left Ventricular Assist Device, Ventricular Dysfunction, Cardiomyopathy, Heart Disease, Cardiovascular Disease, Heart-assist devices, center for heart failure, LVAD
Long-Term Nicotine Treatment of Mild Cognitive Impairment Grant, Ian
Losartan Effects on Emphysema Progression (LEEP) Kalhan, Ravi COPD, Emphysema, coughing, shortness of breath, wheezing
SUSTAIN-IT: Sustaining quality of life of the aged: Heart transplant or mechanical support? Grady, Kathleen L. Center for Heart Failure, MCS, mechanical circulatory support, transplant, VAD
Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia Eskandari, Mark Surgical revascularization, Endovascular revascularization, Amputation, Center for Vascular Disease, CLI , limb ischemia
A Randomized Phase II Study of Topical Steroids as Preemptive Therapy for Epidermal Growth Factor Receptor Inhibitor-Induced Papulopustular Eruption Choi, Jennifer epidermal growth factor inhibitor , egfr inhibitor , acneiform rash, papulopustular eruption , drug rash, topical steroid cream
aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation Lin, Albert LAA, Left Atrial Appendage, Lariat , PVI , ablation , Center for Heart Rhythm Disorders
LIBERTY 2: An International Phase 3 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study to Evaluate Relugolix Co-Administered with and without Low-Dose Estradiol and Norethindrone Acetate in Women with Heavy Menstrual Bleeding Associated with Uterine Fibroids Robins, Jared uterine fibroids, heavy menstrual bleeding, women's health, Relugolix, LIBERTY, FRM Research
Microtubule Polymerization of Modulators for Treating LMNA-Related Dilated Cardiomyopathy Wilcox, Jane Elizabeth LMNA, cardiomyopathy, heart failure, dilated cardiomyopathy, DCM, colchicine, Colcrys, arrhythmia
Protocol Dialysis Outcomes and Practice Patterns Study 2 Isakova, Tamara Peritoneal Dialysis, Dialysis, Chronic Kidney Disease, End stage renal disease, CKD, Research Study, Research , PD , Peritoneal Dialysis Research Study, Peritoneal Dialysis Research, PDOPPS
A Study of the Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis Patients Who Are Naive to TNF Inhibitors Hanauer, Stephen Inflammatory Bowel Disease, IBD, Ulcerative Colitis , Gastroenteritis, Gastrointestinal Diseases, Etrolizumab, Tnf inhibitors
A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate The Efficacy And Safety Of Etrolizumab As An Induction And Maintenance Treatment For Patients With Moderately To Severely Active Crohn’s Disease (Protocol GA29144) Hanauer, Stephen Inflammatory Bowel Disease, IBD, Crohn's Disease , Etrolizumab, Gastroenteritis, Gastrointestinal Diseases
An Open-Label Extension and Safety Monitoring Study of Patients With Moderately to Severely Active Crohn’s Disease Previously Enrolled In The Etrolizumab Phase III Protocol GA29144 (Protocol GA29145) Hanauer, Stephen Inflammatory Bowel Disease, IBD, Crohn's Disease, Gastroenteritis, Gastrointestinal Diseases, Etrolizumab
A collaborative Study to Evaluate the Efficacy of Prospective Post-Induction Infliximab Dosing Based on Trough Levels at Week 12 and 28 in Subjects with Crohn’s Disease (CD) and Ulcerative Colitis (UC) Bellaguarda, Emanuelle Inflammatory Bowel Disease, IBD, Crohn;s Disease, Ulcerative Colitis, Infliximab, Gastroenteritis, Gastrointestinal diseases
LURN: Symptoms of Lower Urinary Tract Dysfunction Research Network Prospective Phenotyping Study Cella, David
A prospective outcomes study in patients with Barrett’s esophagus (BE) associated neoplasia undergoing endoscopic eradication therapy (EET) and esophageal cancer (EAC) Komanduri, Srinadh Barrett's esophagus, esophageal adenocarcinoma
ASSESSMENT OF A MINIMALLY INVASIVE ESOPHAGEAL CYTOLOGY COLLECTION SYSTEM IN PATIENTS WITH BARRETT’S ESOPHAGUS OR GERD SYMPTOMS (B-271) Komanduri, Srinadh Barrett's esophagus
Effect of Aspirin on Biomarkers of Barrett’s Esophagus After Successful Eradication of Barrett’s Esophagus with Radiofrequency Ablation Komanduri, Srinadh Barrett's esophagus, Aspirin, esophageal cancer
A Phase I Study of Ad-RTS-hIL-12, an Inducible Adenoviral Vector Engineered to Express hIL-12 in the Presence of the Activator Ligand Veledimex in Subjects With Recurrent or Progressive Glioblastoma or Grade III Malignant Gliomas Lesniak, Maciej malignant brain tumor, glioblastoma, viral vector
Technology-based Psychosocial Intervention for Symptom Management & HRQOL in Men Living with Advanced Prostate Cancer Penedo, Frank J
Rapidity of Response to Adalimumab Treatment in Patients With Crohn´s Disease Hanauer, Stephen inflammatory bowel disease, IBD, Gastrointestinal Diseases, Methotrexate, ustekinumab, tofacitinib
Acute Extravascular Defibrillation, Pacing and Electrogram Study (ASD2) Knight, Bradley Paul
A phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-Center Study to Investigate the Safety and Efficacy of APD334 in Patients with Moderately to Severely Active Ulcerative Colitis Baidoo, Leonard Inflammatory Bowel Disease, IBD, Ulcerative Colitis
Combined Phase 2b/3, Double-blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Ulcerative Colitis Hanauer, Stephen Inflammatory Bowel Disease, IBD, Ulcerative Colitis, Filgotinib, Remission, Gastrointestinal disease
Continued ESD Training in a Western Country via Live Internet Based Videoconferencing with Expert Japanese Endoscopists Aadam, Abdul ESD
Multi-center Prospective Evaluation of the Clinical Utility of Endoscopic Submucosal Dissection (ESD) in the Western Population Aadam, Abdul ESD
GASTRIC PERORAL ENDOSCOPIC MYOTOMY (G-POEM) FOR TREATMENT OF REFRACTORY GASTROPARESIS: A PILOT STUDY Aadam, Abdul gastroparesis
A Multicenter Randomized Trial of Percutaneous Transhepatic Biliary Drainage vs. Endoscopic Retrograde Cholangiography for Decompression of Suspected Malignant Biliary Hilar Obstruction Keswani, Rajesh N
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Oral RPC1063 as Induction and Maintenance Therapy for Moderate to Severe Ulcerative Colitis Hanauer, Stephen Inflammatory Bowel Disease, IBD, Ulcerative Colitis, gastrointestinal disease
An Extension Study of APD334-003 in Patients with Moderately to Severely Active Ulcerative Colitis Baidoo, Leonard Inflammatory Bowel Disease, IBD, Ulcerative Colitis
A Phase 2 study to investigate the efficacy, safety, and tolerability of six weeks treatment with V565 in subjects with active Crohn’s disease Hanauer, Stephen Inflammatory Bowel Disease, IBD, Crohn's disease , gastroenteritis, gastrointestinal disease
An Open Label Extension And Safety Monitoring Study Of Moderate To Severe Ulcerative Colitis Patients Previously Enrolled In Etrolizumab Phase II/III Studies Hanauer, Stephen inflammatory Bowel Disease, IBD, Ulcerative Colitis , Etrolizumab, Gastrointestinal Diseases
cIRB: AtRial Cardiopathy and Antithrombotic Drugs In prevention After Crypotgenic Stroke Caprio, Fan stroke, apixaban, cryptogenic, aspirin, unknown cause
Effectiveness of Physiologic Testing in PPI Non-Responders Pandolfino, John Erik
A Randomised, Double-Blind, Placebo-Controlled Trial of the Safety and Efficacy of Topical Alicaforsen Enema in Subjects with Active, Chronic, Antibiotic Refractory Primary Idiopathic Pouchitis Hanauer, Stephen Inflammatory Bowel Disease, Pouchitis
A PHASE 2B RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL ADAPTIVE 2-STAGE, MULTI-CENTRE STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ORAL PTG-100 INDUCTION IN SUBJECTS WITH MODERATE TO SEVERE ACTIVE ULCERATIVE COLITIS Bellaguarda, Emanuelle IBD, Ulcerative Colitis , Oral Medication
A Multicenter, Randomized, Double-blind, Placebocontrolled, Parallel-group, Single-dose, Phase 2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IW-1701 in Patients with Achalasia Kahrilas, Peter J
Combined Phase 3, Double-blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Crohn’s Disease Hanauer, Stephen Crohn's Disease, Inflammatory Bowel Disease, IBD, Filgotinib, Remission, Gastrointestinal Diseases
Department of Psychiatry and Behavioral Sciences Research Registry Goldman, Morris B
Beraprost-314d Added-on to Tyvaso® (BEAT) Cuttica, Michael J
A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes Molitch, Mark E Kidney Diseases, Diabetic Nephropathies, Diabetes Mellitus, Diabetes Complications, Uric acid, Allopurinol, Glomerular filtration rate, Coronary artery disease
EFFECTS OF DAPAGLIFLOZIN ON BIOMARKERS, SYMPTOMS AND FUNCTIONAL STATUS IN PATIENTS WITH PRESERVED EJECTION FRACTION HEART FAILURE (PRESERVED-HF TRIAL) Khan, Sadiya Heart Failure, T2DM, Type 2 Diabetes, prediabetes, diabetes, HFpEF
A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis Dematte D'Amico, Jane E
A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus Ramsey-Goldman, Rosalind
xIRB A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate Efficacy and Safety of Lenabasum in Diffuse Cutaneous Systemic Sclerosis Varga, John systemic sclerosis, scleroderma, treatment
NU 16C01: A Phase 0 first-in-human study using NU-0129: a spherical nucleic acid (SNA) gold nanoparticle targeting BCL2L12 in recurrent glioblastoma multiforme or gliosarcoma patients Kumthekar, Priya
BI 695501 versus Humira® in patients with active Crohn’s disease: a randomized, double-blind, multicenter, parallel group, exploratory trial comparing efficacy, endoscopic improvement, safety, and immunogenicity Hanauer, Stephen Crohn Disease , Crohn's Disease , Inflammatory Bowel Diseases , Gastroenteritis , Gastrointestinal Diseases , Digestive System Diseases , Intestinal Diseases , Adalimumab , Anti-Inflammatory Agents , Antirheumatic Agents
AMPLATZER™ Amulet™ Left Atrial Appendage (LAA) Occluder Randomized Controlled Trial Knight, Bradley Paul Atrial Fibrillation, Left Atrial Appendage, LAA
Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis: EARLY TAVR trial Davidson, Charles J Aortic Stenosis, TAVR, Aortic Valve Disease, PARTNER, EARLY TAVR, SAPIEN, THV
FLUTicasone in Eosinophilic esophagitis (FLUTE): A Randomized, Double-blind, Placebo-controlled, Dose-ranging, and Maintenance Study of APT-1011 in Subjects with Eosinophilic Esophagitis Hirano, Ikuo
A Phase 3, Multicenter, Open-label Continuation Study with Budesonide Oral Suspension (BOS) for Adolescent and Adult Subjects with Eosinophilic Esophagitis (EoE) Hirano, Ikuo
Expanded Access Protocol of Patisiran for Patients with Hereditary Transthyretin-Mediated Amyloidosis (hATTR Amyloidosis) With Polyneuropathy Ajroud-Driss, Senda Hereditary Transythretin-Mediated Amyloidosis, hATTR Amyloidosis, hATTR, Familial Amyloid Polyneuropathy, FAP, Amyloidosis, Patisiran, Alnylam
Effect of MD1003 in Progressive Multiple Sclerosis: a Randomized Double Blind Placebo Controlled Study Cohen, Bruce Arnold Multiple Sclerosis, Primary Progressive MS, Secondary Progressive MS, Progressive MS, Biotin, MD1003
A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared with Investigator’s Choice in HLA-A*0201 Positive Patients with Previously Untreated Advanced Uveal Melanoma Chandra, Sunandana
(CIRB) A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis Rinella, Mary Eugenia NASH, Fibrosis, Fatty liver disease
Edwards Cardioband™ Tricuspid Valve Reconstruction System Early Feasibility Study Davidson, Charles J Tricuspid, Transcatheter, Valve Reconstruction, tricuspid regurgitation, Cardioband
xIRB A Randomized, Double-blind, Placebo-controlled, Phase 3 Multicenter Study to Evaluate the Safety and Efficacy of Abaloparatide-SC for the Treatment of Men with Osteoporosis Schnitzer, Thomas J bone health, osteoporosis, male osteoporosis, fracture
MOLECULAR BASIS OF ALTERED DRUG METABOLISM DURING PREGNANCY (STUDY 2: DEFINING FACTORS RESPONSIBLE FOR TEMPORAL CHANGES IN CYP3A4-MEDIATED DRUG METABOLISM DURING PREGNANCY) Wisner, Katherine nifedipine, pregnancy, pregnant, women, metabolism, drug, blood pressure, hypertension
ELUCDITATING THE MOLECULAR MECHANISMS UNDERLYING CYP2D6 INDUCTION DURING PREGNANCY Wisner, Katherine pregnant, retinoid, vitamin a, pregnancy, asher, metabolism, women
Stellate Ganglion Blockade for the Management of Vasomotor Symptoms Walega, David R hot flash , hot flashes , night sweats, hot flushes
A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1 Schnitzer, Thomas J CRPS , RSD, Pain
Bump on the Ball: Impact of a Prenatal Exercise & Education Program on Birth Outcomes & Maternal Quality of Life Gaupp, Christina Lewicky singleton pregnancy, second trimester, pregnancy exercise, pregnancy fitness, pregnancy education
Sacral Neuromodulation in Dual Incontinence: Ultrasound and Afferent Nerve Sensation Assessment (SaNDI) Kenton, Kimberly dual incontinence, nerve stimulation
Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip Schnitzer, Thomas J osteoarthritis, knee pain, hip pain, pain
Permanent versus delayed-absorbable monofilament suture for vaginal graft attachment during minimally-invasive total hysterectomy and sacrocolpopexy: A Randomized Clinical Trial Kenton, Kimberly permanent stitches, delayed absorbable stitches, pelvic organ prolapse, uterus removal
(xIRB) NCI 9767: An Open Label, Multicenter, Single arm Phase II study to evaluate the Activity and Tolerability of the novel mTOR Inhibitor, MLN0128 (TAK-228), in patients with Locally Advanced or Metastatic Transitional Cell Carcinoma of the urothelial tract whose tumors harbor a TSC1 and/or TSC2 mutation. Morgans, Alicia
Physical activity and DNA methylation among women with high breast density Hibler, Elizabeth breast density, physical activity, DNA methylation
Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee Schnitzer, Thomas J knee pain, hip pain, osteoarthritis, pain
VESPR: Vaginal Electrical Stimulation for Postpartum neuromuscular Recovery Gaupp, Christina Lewicky vaginal tear, obstetric tear, vaginal electrical stimulation, stimulation, pregnancy , postpartum
The association between the urinary microbiome and response to sacral neuromodulation in women with urgency urinary incontinence Mueller, Margaret urinary bacteria , nerve stimulation, overactive bladder
Postpartum GRANulation Tissue: The GRANT Study Gaupp, Christina Lewicky granulation tissue, postpartum recovery, obstetric tear
Fibroids and Urinary Symptoms Study (FUSS) Survey Kenton, Kimberly fibroids, pelvic floor, urinary symptoms, uterine fibroids, MRI
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF A DOSE TITRATION REGIMEN FOR THE SUBCUTANEOUS ADMINISTRATION OF TANEZUMAB IN SUBJECTS WITH OSTEOARTHRITIS OF THE HIP OR KNEE Schnitzer, Thomas J osteoarthritis , hip pain , knee pain, pain
REDUCE LAP-HF RANDOMIZED TRIAL II: A study to evaluate the Corvia Medical, Inc. IASD® System II to REDUCE Elevated Left Atrial Pressure in Patients with Heart Failure Ricciardi, Mark heart failure
Specimen and Data Study for Ovarian Cancer Early Detection and Prevention Shulman, Lee P ovarian epithelial cancer, hereditary breast/ovarian cancer (BRCA1, BRCA2), fallopian tube cancer, ovarian germ cell tumor, ovarian sarcoma, ovarian stromal cancer, endometrial cancer, uterine sarcoma, vaginal cancer, cervical cancer, vulvar cancer, uterine leiomyomata
Morning Light Treatment at Home to Improve Glucose Metabolism in People at Increased Risk for Type 2 Diabetes Knutson, Kristen prediabetes, morning light treatment, sleep, circadian misalignment
NCI 2015-06-04 Phase IIB trial of neoadjuvant oral tamoxifen versus transdermal 4-hydroxytamoxifen in women with DCIS of the breast Khan, Seema Ahsan Ahsan
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer Flaum, Lisa estrogen receptor-positive breast cancer, HER2-negative breast cancer, stage IA breast cancer, stage IB breast cancer, stage II breast cancer, stage IIIA breast cancer, stage IIIB breast cancer, stage IIIC breast cancer, progesterone receptor-positive breast cancer, male breast cancer
MULTIETHNIC FINE-MAPPING OF POLYCYSTIC OVARY SYNDROME SUSCEPTIBILITY LOCI (R01 HD085227) Dunaif, Andrea E Polycystic Ovary Syndrome, PCOS , Infertility, Ovary, Endocrine Disorder, Irregular Periods, Acne, Metformin , Spironolactone, Overweight, Obese
Clinician-input study: how the Fox Insight mobile application can influence treatment and care (CIS-PD) Simuni, Tatyana parkinson's disease, PD, wearable technology, Iphone, apple watch
Cardiovascular Outcomes Assessment of the MitraClip Therapy Percutaneous Therapy for High Surgical Risk Patients Ricciardi, Mark mitral regurgitation , center for valve disease, valve, heart failure, center for heart failure, coapt, mitraclip
Maternal and Neurodevelopmental Outcomes of in Utero Antiepileptic Drug (AED) Exposure Gerard, Elizabeth Erway Epilepsy, Pregnancy
Non-Invasive Marker of Ovarian Reserve in Women with Epilepsy Gerard, Elizabeth Erway
Prospective Phase II Study of Cytochrome C Oxidase Activity as a Novel Biomarker In Subjects With Newly Diagnosed Primary Glioblastoma Multiforme Kumthekar, Priya gliobastoma, biomarker, GBM
Alliance A221101: A Phase III Randomized, Double-Blind Placebo Controlled Study Of Armodafinil (Nuvigil®) To Reduce Cancer-Related Fatigue In Patients With High Grade Glioma Dixit, Karan
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate The Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Subjects with Active Crohn's Disease. Hanauer, Stephen Crohn's Disease , GED-0301 , Mongersen , IBD , Crohn Disease , Inflammatory Bowel Diseases , Gastroenteritis , Digestive System Diseases , Gastrointestinal Diseases , Intestinal Diseases
Phase IIB TL + YCWP + DC in Melanoma Chandra, Sunandana
Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer Matei, Daniela Cancer, Recurrent, Ovary, Fallopian Tube, Primary Peritioneal, Phase II, Platinum Resistant
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial) Mohindra, Nisha
ACUpuncture after HEART Surgery Feingold, Kim R Center for Preventive Cardiology, acupuncture, mitral valve, aortic valve, cardiac behavioral medicine
A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications Macken, Micheal P Lacosamide, Vimpat, Epilepsy, Children, Primary Generalized Tonic Clonic seizures, Idiopathic Generalized Epilepsy, Adults
Genetic causes and pathogenic mechanisms of adult epilepsies Gerard, Elizabeth Erway
Efficacy and Safety of Eslicarbazepine Acetate as First Add-on to Levetiracetam or Lamotrigine Monotherapy or as Later Adjunctive Treatment for Subjects with Uncontrolled Partial-onset Seizures: A Multicenter, Open-label, Non-randomized Trial (Protocol SEP093-701) Gerard, Elizabeth Erway
Microburst VNS Therapy Feasibility Study in Subjects with Refractory Epilepsy Macken, Micheal P
SDF1 Plasmid Treatment for Patients With Peripheral Artery Disease Ho, Karen Center for Vascular Disease, PAD, peripheral artery disease
A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Dupilumab Administered Concomitantly with Topical Corticosteroids in Patients, ≥6 YEARS TO <12 Years of Age, With Severe Atopic Dermatitis Paller, Amy atopic dermatitis, eczema, itch, pediatric
Longitudinal Early-onset Alzheimer’s Disease Study (LEADS) Rogalski, Emily Joy
A Phase 3 Randomized, Double-Blind, Multi-Dose, Placebo and Naproxen-Controlled Study to Evaluate the Efficacy and Safety of Fasinumab in Patients with Pain Due to Osteoarthritis of the Knee or Hip Schnitzer, Thomas J arthritis, osteoarthritis, knee pain, hip pain, pain management, pain
A Phase 3, Randomised, Rater-Blinded, Multi-Centre Study to Evaluate the Efficacy and Safety of WTX101 Administered for 48 Weeks Versus Standard of Care in Wilson Disease Subjects Aged 18 and Older with an Extension Phase of up to 60 Months. Bega, Danny Wilson's disease, Standard of Care Therapy
A Proof of Concept Study to Investigate the Effect of IPT803 Adjunct Treatment in Patients with Parkinson’s Disease. Bega, Danny
National Parkinson Foundation Patient Registry Simuni, Tatyana Patient Outcomes Project, Parkinson Foundation, Parkinson's Disease
Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF Shah, Sanjiv J heart failure, exercise capacity
A Randomized, Double-Blind, Placebo-Controlled, 52-Week Phase II Study to Evaluate the Efficacy of Intravenous RO7046015 (PRX002) in Participants with Early Parkinson’s Disease with a 52 Week Blinded Extension (PASADENA) Simuni, Tatyana Early Parkinson's Disease
MY PATHWAY: AN OPEN-LABEL PHASE IIA STUDY EVALUATING TRASTUZUMAB/PERTUZUMAB, ERLOTINIB, VEMURAFENIB/COBIMETINIB, VISMODEGIB, ALECTINIB, AND ATEZOLIZUMAB IN PATIENTS WHO HAVE ADVANCED SOLID TUMORS WITH MUTATIONS OR GENE EXPRESSION ABNORMALITIES PREDICTIVE OF RESPONSE TO ONE OF THESE AGENTS Villaflor, Victoria Advanced Solid Tumors; Mutations; , Clinical Trial; Research; , phase 2;
Phase II study of front line therapy with nivolumab and salvage nivolumab + ipilimumab in patients with advanced renal cell carcinoma Sosman, Jeffrey Renal Cell Carcinoma; Kidney Cancer; Clinical Trial; Research; Immunotherapy; Phase 2; Investigational
REDO-FIRM - Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures Knight, Bradley Paul AF, atrial fibrillation, heart rhythm disorder, arrhythmia, ablation
A multi-centre, randomized, double-blind (sponsor open), placebo-controlled, repeat-dose, proof of mechanism study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and explore efficacy of GSK2330811 in participants with diffuse cutaneous systemic sclerosis Varga, John scleroderma, systemic sclerosis, skin fibrosis, treatment
A Phase 2, Open-Label, 2-Cohort Study of INCB050465, a PI3K Inhibitor, in Subjects With Relapsed or Refractory Marginal Zone Lymphoma With or Without Prior Exposure to a BTK Inhibitor (CITADEL-204) Ma, Shuo Lymphoma; Marginal Zone; PI3 Kinase; Phase 2; Open-label; Investigational; Research;
The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE Isakova, Tamara
SHORT-TERM EFFECTS OF NICOTINAMIDE AND LANTHANUM CARBONATE ON PHOSPHATE HOMEOSTASIS IN HEALTHY VOLUNTEERS Isakova, Tamara
Understanding Outcomes with the EMBLEM™ S-ICD in Primary Prevention Patients with Low Ejection Fraction Knight, Bradley Paul ICD, Cardiac Defibrillator, heart rhythm disorder, arrhythmia, S-ICD
Exercise in Genetic Cardiovascular Conditions: Lifestyle and Exercise in Hypertrophic Cardiomyopathy: “LIVE-HCM”/ Lifestyle and Exercise in Long QT Syndrome: “LIVE-LQTS” Choudhury, Lubna Hypertrophic Cardiomyopathy, HCM, Cardiomyopathy, arrhythmia, Long QT Syndrome, LQTS, exercise
(xIRB) NCI cIRB - NRG GU002: PHASE II-III TRIAL OF ADJUVANT RADIOTHERAPY AND ANDROGEN DEPRIVATION FOLLOWING RADICAL PROSTATECTOMY WITH OR WITHOUT ADJUVANT DOCETAXEL Sachdev, Sean
Evaluation of the Thoraflex™ Hybrid Device for Use in the Repair or Replacement of the Ascending Aorta, Aortic Arch and Descending Aorta in an Open Surgical Procedure. Protocol #: Hybrid-002 Malaisrie, S Chris Chris aorta, vascular disease, aneurysm
Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE) Kho, Abel N cardiovascular disease, heart disease, aspirin, dose
Induction of Donor Specific Tolerance in Recipients of Living Kidney Allografts by Donor FCRx Infusion Leventhal, Joseph R Kidney transplant, Tolerance, Marrow/Enriched Hematopoetic Stem Cell Transplant
Asteria Zee, Phyllis C sleep, performance, overnight
Language in Primary Progressive Aphasia Mesulam, Marek-Marsel
Environmental Influences on Child Health Outcomes (ECHO) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Fetal Growth Studies Grobman, William A environmental exposures, pediatric population, maternal fetal medicine, asthma, obesity, postnatal outcomes, neurodevelopment, autism, attention deficit hyperactivity disorder
A Phase IIA, Single-Center, Randomized, Placebo-Controlled, Double-Blind Study to Assess the Efficacy of CRTh2 Antagonist AZD1981 in Patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) Peters, Anju Tripathi nasal polyps, chronic sinusitis, allergy, rhinosinusitus, congestion, facial pressure, loss of taste and smell
A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase 3 Efficacy and Safety Study Of Benralizumab in Patients with Severe Nasal Polyposis (OSTRO) Peters, Anju Tripathi rhinosinuitus, congestion, facial pressure, loss of taste and smell, nasal polyps, chronic sinusitis, allergy , nasal polyposis
Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma Chandra, Sunandana
A PHASE 1B, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER, SINGLE ASCENDING DOSE STUDY TO ASSESS THE SAFETY, EFFICACY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF DS-1040B WHEN ADDED TO STANDARD OF CARE ANTICOAGULATION THERAPY IN SUBJECTS WITH ACUTE SUBMASSIVE PULMONARY EMBOLISM Schimmel, Daniel Richard pulmonary embolism, thrombotic disease
D-Cycloserine for the Treatment of Chronic, Refractory Low Back Pain Schnitzer, Thomas J low back pain, pain , back pain, chronic low back pain
Enhancing Maneuverability Following Incomplete Spinal Cord Injury Gordon, Keith Edward walking, maneuvers , treadmill
A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of VM202 to Treat Chronic Non-healing Foot Ulcers in Diabetic Patients with Concomitant Peripheral Arterial Disease (PAD) Ho, Karen diabetic foot ulcer, peripheral artery diseas
Hepatocyte Growth Factor to Improve Functioning in PAD: The HI-PAD Study McDermott, Mary Douglas
Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery Halverson, Amy L stage IIA rectal cancer, stage IIIA rectal cancer, stage IIIB rectal cancer
Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA Mittal, Bharat B
Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancer Chae, Young Kwang Veliparib, PARP - Poly (ADP) ribose polymerase, ABT-888, Extensive Stage Smal Cell Lung Cancer
OT-15-001: A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy Kumthekar, Priya
A Phase 2/3 Multicenter, Open-label, 3-arm, 2-stage Randomized Study of ASP2215 (Gilteritinib), Combination of ASP2215 Plus Azacitidine and Azacitidine Alone in the Treatment of Newly Diagnosed Acute Myeloid Leukemia with FLT3 Mutation in Patients Not Eligible for Intensive Induction Chemotherapy Dinner, Shira
Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects With Moderate to Severe Crohn's Disease Hanauer, Stephen Crohn's Disease, inflammatory Bowel Disease, IBD, Adalimumab, Mucosal Ulceration, Gastrointestinal Disease
Breaking Down Financial Barriers: A Pilot Study to Determine the Feasibility, Acceptance, and Effectiveness of In vitro Maturation in Low Resource Populations Robins, Jared in vitro maturation, IVM, low income, infertility, PCOS, pregnancy, FRM Research
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) Weintraub, Sandra
A multi-center, double-blind, placebo-controlled Phase 2b study to evaluate the efficacy and safety of macitentan in subjects with heart failure with preserved ejection fraction and pulmonary vascular disease Freed, Benjamin Heart Failure, HFpEF, pulmonary vascular disease
Transformative Research In Diabetic Nephropathy (TRIDENT) (SP0043185) Isakova, Tamara chronic kidney diease, kidney disease, diabetes, renal biopsy, kidney biopsy, research study, research, study, diabetes mellitus, diabetic nephropathy
A Study to Evaluate the Effect of ALKS 3831 Compared to Olanzapine on Body Weight in Young Adults with Schizophrenia, Schizophreniform, or Bipolar I Disorder Who are Early in Their Illness Rado, Jeffrey Psychosis, Schizophrenia, Schizophreniphorm, Bipolar Type 1, Mania, Olanzapine, Samidorphan, Weight gain, Atypical antipsychotic, ALK3831 , Pscyhotic, Delusions, Hallucinations, Paranoia, Bipolar
xIRB Efficacy and safety of 3 doses of S201086/GLPG1972 administered orally once daily in patients with knee osteoarthritis. A 52-week international, multi-regional, multi-center, randomized, double-blind, placebo-controlled, dose-ranging study. Schnitzer, Thomas J osteoarthritis, knee pain, arthritis, knee stiffness, joint pain, joint stiffness
Prospective, Multicenter, Multidisciplinary, Controlled Clinical Investigation Evaluating the Safety and Efficacy of PerClot® Polysaccharide The C.L.O.T. Investigation System Malaisrie, S Chris Chris Hemostat, PerClot, Cardiovascular Surgery, Cardiac, Cardiac Surgery
Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy Donnelly, Eric cervical adenocarcinoma, cervical adenosquamous cell carcinoma, cervical squamous cell carcinoma, stage IA cervical cancer, stage IB cervical cancer, stage IIA cervical cancer
Super Aging Study: Correlates of Active Engagement in Life in the Elderly Rogalski, Emily Joy SuperAging, Memory, Aging
Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be Grobman, William A nulliparity, pregnant women, pregnancy outcomes, pregnancy complications
Transplant Recipients Undergoing Therapy Intended to Achieve Transplant Tolerance Friedewald, John J
Outcomes of patients undergoing incompatible donor kidney transplantation at Northwestern University Friedewald, John J
NU 16I01: Phase I/Ib study of nivolumab in combination with Therasphere (yttrium-90) in patients with advanced hepatocellular carcinoma. Kalyan, Aparna
RESTORE: A clinical study of patients with symptomatic neuRogenic orthostatic hypotEnsion to assess Sustained effecTs Of dRoxidopa thErapy Zadikoff, Cindy Orthostatic Hypotension, RESTORE
A Phase 2, single arm, multi-center, open label trial Combining Optune with concurrent Bevacizumab in the setting of Recurrent or Progressive Meningioma Kumthekar, Priya
Biorepository of Specimens from Normal Volunteers Friedewald, John J
Effects of Intravenous Ferric Carboxymaltose on Phosphorus and FGF23 Levels Mehta, Rupal FGF23, phosphorus , ferric carboxymaltose
NRG-GY006: A Randomized phase II trial of radiation therapy and cisplatin alone or in combination with intravenous triapine in women with newly diagnosed bulky stage IB2, or stage II, IIIB, or IVA cancer of the uterine cervix or stage II-IVA vaginal cancer. Shahabi, Shohreh
A Pilot Study to Evaluate the Efficacy and Safety of Secukinumab in the Treatment of Patients with Ichthyoses Sub-Study: A Multicenter Study with a Randomized, Double-Blind, Placebo-Controlled Period, Followed by an Open-Label Maintenance Dosing Period to Evaluate the Efficacy and Safety of Secukinumab in Patients with Ichthyoses Paller, Amy ichthyosis, lamellar ichthyosis, netherton syndrome, epidermolytic hyperkeratosis, congenital ichthyosiform erythroderma

Registar — created by NUBIC for Northwestern University