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Recruiting Studies

Title Investigator Keywords
Northwestern Scleroderma Program Patient Registry Hinchcliff, Monique E scleroderma , skin fibrosis , systemic sclerosis , autoimmune
Safety, Tolerability, and Preliminary Efficacy Study of ALS-357 in Patients With Cutaneous Metastatic Melanoma Kuzel, Timothy Michael Cutaneous Metastatic Melanoma
Radiation Therapy With or Without Cisplatin in Treating Patients With Recurrent Endometrial Cancer Shahabi, Shohreh
Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer Benson III, Al B recurrent colon cancer, stage IV colon cancer, recurrent rectal cancer, stage IV rectal cancer
Pentostatin, Cyclophosphamide, and Rituximab Followed By Lenalidomide in Treating Patients With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia Ma, Shuo refractory chronic lymphocytic leukemia, B-cell chronic lymphocytic leukemia
ECOG-ACRIN 8143 A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Localized Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC) Sosman, Jeffrey
Transthyretin-Associated Amyloidoses Outcome Survey (THAOS) Shah, Sanjiv J TRANSTHYRETIN, AMYLOIDOSIS, TRANSTHYRETIN AMYLOIDOSIS
Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patients Altman, Jessica K
Predictive Ability of Gene Expression Signatures in Skin as SSc Biomarkers Hinchcliff, Monique E scleroderma , inflammatory, skin fibrosis
Rituximab and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Non-Hodgkin's Lymphoma Winter, Jane Norma stage I adult diffuse large cell lymphoma, contiguous stage II adult diffuse large cell lymphoma, noncontiguous stage II adult diffuse large cell lymphoma, stage III adult diffuse large cell lymphoma, stage IV adult diffuse large cell lymphoma
Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer Schink, Julian C fatigue, neurotoxicity, endometrial clear cell carcinoma, endometrial papillary serous carcinoma, endometrial adenoacanthoma, endometrial adenocarcinoma, endometrial adenosquamous cell carcinoma, stage IA endometrial carcinoma, stage IB endometrial carcinoma, stage II endometrial carcinoma
The Effect of Neuraxial Analgesia on Maternal Breastfeeding Wong, Cynthia A Epidural Labor Analgesia, Pain, Infant, Breastfeeding
Intranasal oxytocins effect on facial affect discrimination in schizophrenia Goldman, Morris B
Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE) Rodriguez Alvarez, Heron Rodriguez thoracic aneurysm, thoracic aortic aneurysms, Thoracic Endovascular Aneurysm Repair (TEVAR), Talent Thoracic Stent Graft
Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients Gallon, Lorenzo Sirolimus, Rapamune, Immunosuppression, Renal allograft function, Lymphocytes function
Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer Shahabi, Shohreh
Lower extremity motor coordination with and without nervous system injury Sukal Moulton, Theresa Sukal
Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Agulnik, Mark
Transverse Abdominis Plane (TAP) Block After Cesarean Delivery Yaghmour, Edward Talaat Cesarean Delivery, Ropivicaine, TAP block
HLA-Identical Sibling Renal Transplant Tolerance Leventhal, Joseph R Transplants, Kidney Transplantation, Immunosuppression, HLA Antigens, Stem Cells, Bone Marrow
Chicago Lupus Database Ramsey-Goldman, Rosalind lupus
Characteristics of the Stretch Reflex Response in Various Joints Perreault, Eric
DERMATOLOGY TISSUE ACQUISITION AND REPOSITORY West, Dennis P biopsy, tissue, biorepository, dermatology
Radiolabeled Glass Beads in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Salem, Riad adult primary hepatocellular carcinoma, localized unresectable adult primary liver cancer, advanced adult primary liver cancer
Radiolabeled Glass Beads in Treating Patients With Metastatic Liver Cancer That Cannot Be Removed by Surgery Salem, Riad liver metastases, advanced adult primary liver cancer
A Study to Evaluate Chronic Hepatitis C Infection in Adult Transplant Recipients Levitsky, Josh Chronic Hepatitis, Hepatitis C Virus, Hepatitis C Genotype 1, Interferon-Free, Liver Transplant, Renal Transplant
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia Frankfurt, Olga
A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy Frankfurt, Olga
Chemoembolization Versus Radioembolization in Treating Patients With Liver Cancer That Cannot Be Treated With Radiofrequency Ablation Or Surgery Salem, Riad advanced adult primary liver cancer, localized unresectable adult primary liver cancer, recurrent adult primary liver cancer, adult primary hepatocellular carcinoma
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients Wong, Cynthia A Preeclampsia, Spinal Anesthesia, Hypotension, Cesarean Delivery, Phenylephrine, Ephedrine
SAPPHIRE Worldwide: Stenting and Angioplasty With Protection in Patients At High-Risk for Endarterectomy Eskandari, Mark Carotid Artery Stenting (Endovascular)
Genes in Diabetic Retinopathy Project Lyon, A Thayer
Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery Kuzel, Timothy Michael stage IV melanoma, acral lentiginous malignant melanoma, mucosal melanoma, recurrent melanoma, stage IIIA melanoma, stage IIIB melanoma, stage IIIC melanoma
NIH All of Us Research Program Precision Medicine Initiative® Precision Medicine Initiative Cohort Program Healthcare Provider Organization Enrollment Centers Greenland, Philip Precision Medicine, genetics, individualized medicine, health care, environment, lifestyle, biology, biobank, technology, behavior
A Multicenter Group to Study Acute Liver Failure. Long-term Outcomes of Acute Liver Failure Study Group Patients Ganger, Daniel R acute liver failure, acute liver injury
Reduction in Allergic Antibody in Human Allergic Subjects Greenberger, Paul Allen
Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III Jahromi, Babak intracerebral hemorrhage, ICH, brain hemorrhage, minimally invasive surgery, rt-PA
Mediators of Atherosclerosis in South Asians Living in America Kandula, Namratha R
Endoscopic Ultrasound-guided Celiac Plexus Neurolysis in the Management of Pain in Abdominal Non-pancreatic Malignancies Keswani, Rajesh N
S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma Winter, Jane Norma stage III adult Hodgkin lymphoma, stage IV adult Hodgkin lymphoma, adult lymphocyte depletion Hodgkin lymphoma, adult lymphocyte predominant Hodgkin lymphoma, adult mixed cellularity Hodgkin lymphoma, adult nodular sclerosis Hodgkin lymphoma, HIV infection
Alterations in Gene Expression in the Scleroderma Esophagus Hinchcliff, Monique E scleroderma , autoimmune , heartburn , GERD, systemic sclerosis, esophagus, inflammatory
Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy Donnelly, Eric
Induction of Donor Specific Tolerance in Recipients of Living Kidney Allografts by Donor FCRx Infusion Leventhal, Joseph R Kidney transplant, Tolerance, Marrow/Enriched Hematopoetic Stem Cell Transplant
Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma Raizer, Jeffrey J neurotoxicity, adult diffuse astrocytoma, adult oligodendroglioma, recurrent adult brain tumor, adult mixed glioma
Make Better Choices Spring, Bonnie Physical Activity, Sedentary Lifestyle, Diet, Health Behavior
Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis Kalapurakal, John A spinal bone metastases, pain
The Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy Ganger, Daniel R Hepatic Encephalopathy, Liver Failure, Hepatic Insufficiency, Liver Diseases, Brain Diseases, Rifaximin, Cirrhosis
Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer Mulcahy, Mary Frances
A Proposal to Test the Efficacy and Tolerability of Bortezomib in Pulmonary Chronic GVHD Jain, Manu Bortezomib GVHD Bronchiolitis Obliterans
Platelet-Orientated Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial Mendelson, Scott
(CIRB) AURORA: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Cenicriviroc for the Treatment of Liver Fibrosis in Adult Subjects with Nonalcoholic Steatohepatitis Rinella, Mary Eugenia NASH
Second Curettage in Treating Patients With Persistent Non-Metastatic Gestational Trophoblastic Tumor Shahabi, Shohreh nonmetastatic gestational trophoblastic tumor, hydatidiform mole
Carboplatin, Paclitaxel and Gemcitabine With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Shahabi, Shohreh
Combined Spinal Epidural Urinary Retention Bauchat, Jeanette Urinary Retention, Urinary Catheter, Bacteriuria
Ranolazine and Pulmonary Hypertension Shah, Sanjiv J Angina, Right Ventricular Ischemia, Pulmonary Arterial Hypertension, Pulmonary Hypertension
Yttrium Y 90 Glass Microspheres and Capecitabine in Treating Patients With Liver Cholangiocarcinoma or Liver Metastases Mulcahy, Mary Frances advanced adult primary liver cancer, liver metastases, adult primary cholangiocellular carcinoma
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery Benson III, Al B
Self Administered Cognitive Behavior Therapy for Irritable Bowel Syndrome Keefer, Laurie
Alzheimer's Disease Core Center Mesulam, Marek-Marsel Alzheimer's Disease, Mild Cognitive Impairment, Dementia, Registry, Brain, Brain Donation
Neural Mechanisms in Sensory Reception and Processing in the Healthy Adult (VA RR&D Grant # B3302K) Pape, Theresa L Bender L
Dermatopathology Tissue Repository for Research West, Dennis P
Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia Khan, Seema Ahsan Ahsan
Screening For a Registry (Database) and Future Participation In Asthma and Chronic Obstructive Lung Disease (COPD) Clinical Research Studies Kalhan, Ravi ephysema, chronic bronchitis, shortness of breath, coughing, chest tightness, lungs, inhaler
Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed By the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed By Surgery Hayes, John P
Development of New MRI Protocols Parrish, Todd B
Study to Identify Clinical, Imaging and Biologic Markers of Parkinson Disease Progression Simuni, Tatyana Parkinson, Bio-markers, Neurodegenerative disorder, Imaging, Prodromal
Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma Kumthekar, Priya
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer MacVicar, Gary R
Radiation Therapy With Concomitant and Adjuvant Temozolomide or Radiation Therapy With Adjuvant PCV or Temozolomide Alone in Treating Patients With Anaplastic Glioma Kumthekar, Priya adult anaplastic astrocytoma, adult anaplastic oligodendroglioma, adult mixed glioma
Radiation Therapy With or Without Temozolomide in Treating Patients With Anaplastic Glioma Kumthekar, Priya adult anaplastic oligodendroglioma, adult anaplastic astrocytoma
CENTER FOR BEHAVIORAL INTERVENTION TECHNOLOGIES (CBITs) RESEARCH SUBJECT RECRUITMENT REGISTRY Mohr, David C Depression, Anxiety, Smartphone, Health, Technology, Internet
Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed Persistent or Recurrent Uterine, Ovarian, Fallopian Tube, or Peritorium Cavity Cancer Shahabi, Shohreh
The ANSWER Program® : American Norditropin® Studies: Web Enabled Research (StudyID: HGH-2149); An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin® (Human Growth Hormone) Molitch, Mark E
Effect of Weight Loss on Breast Density Using Digital Mammography and MRI in Women Who Are At Increased Risk For Breast Cancer Hansen, Nora M
Alzheimer's Disease Neuroimaging Initiative 2 Rogalski, Emily Joy amyloid, plaques, neuroimaging, biomarkers, cognition disorder, early detection, Amnestic MCI, pre-dementia, dementia, Alzheimer's disease
Everolimus Versus Placebo in Head and Neck Cancer Agulnik, Mark Squamous Cell Cancer
Serial Blood and Urine Monitoring Study in Kidney Transplant Recipients Friedewald, John J Transplantation, Kidney, Biological Markers
Exceptional Cognitive Aging: Neuropsychologic, Anatomic and Pathologic Correlates Rogalski, Emily Joy
An Exploratory Phase II Study to Determine the Tolerability, Safety, and Activity of a Novel Vasopressin 1a Receptor Antagonist (SRX246) in Irritable Subjects with Huntington's Disease (HD) Bega, Danny irritability, behavioral problems, Huntington's, HD
Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer Raizer, Jeffrey J Breast Cancer
BLP25 Liposome Vaccine and Bevacizumab After Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery Mohindra, Nisha stage IIIA non-small cell lung cancer, stage IIIB non-small cell lung cancer, adenocarcinoma of the lung, bronchoalveolar cell lung cancer, large cell lung cancer
Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy Anderson, Allen Heart Failure, Decompensated Heart Failure, Acute Decompensated Heart Failure, Hemodynamic Monitoring, Implantable Pressure Monitor, Left Atrial Pressure Monitoring
4R for Guideline Indicated BRCA Testing of Breast Center Patients Simon, Melissa A
Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation. Agulnik, Mark
cIRB: Topiramate as a disease altering therapy for Cryptogenic Sensory Peripheral Neuropathy (CSPN) Menichella, Daniela Pain, sensory loss, imbalance, obesity
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery Benson III, Al B adenocarcinoma of the colon, stage III colon cancer
Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer Berry, Emily
Myoelectric-computer interface to reduce muscle co-activation after stroke Slutzky, Marc W
Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Neuropathy Allen, Jeffrey A chemotherapy, peripheral neuropathy, paclitaxel, breast cancer
EHR-based Health Literacy Strategy to Promote Medication Therapy Management Persell, Stephen D
Bendamustine Hydrochloride and Rituximab With or Without Bortezomib Followed by Rituximab With or Without Lenalidomide in Treating Patients With High-Risk Stage II, Stage III, or Stage IV Follicular Lymphoma Winter, Jane Norma contiguous stage II grade 1 follicular lymphoma, contiguous stage II grade 2 follicular lymphoma, contiguous stage II grade 3 follicular lymphoma, noncontiguous stage II grade 1 follicular lymphoma, noncontiguous stage II grade 2 follicular lymphoma, noncontiguous stage II grade 3 follicular lymphoma, stage III grade 1 follicular lymphoma, stage III grade 2 follicular lymphoma, stage III grade 3 follicular lymphoma, stage IV grade 1 follicular lymphoma, stage IV grade 2 follicular lymphoma, stage IV grade 3 follicular lymphoma
A Study of Alpharadin® With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC) Kuzel, Timothy Michael The target population is patients with bone metastasis from castration-resistant prostate cancer intended for treatment with docetaxel
Enroll-HD: A Prospective Registry Study in a Global Huntington’s Disease Cohort Bega, Danny Huntington's disease, Registry Study
Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer Khan, Seema Ahsan Ahsan male breast cancer, stage IV breast cancer
Incidence of Headache Following an Unintentional Dural Puncture Peralta, Feyce Postdural puncture headache, Intrathecal morphine, Intrathecal catheter, Headache, Labor and delivery, Unintentional dural puncture
A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia Altman, Jessica K AML
Alemtuzumab-Ofatumumab in Previously Untreated Symptomatic Chronic Lymphocytic Leukemia Ma, Shuo
Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia Altman, Jessica K untreated adult acute myeloid leukemia, secondary acute myeloid leukemia, adult acute minimally differentiated myeloid leukemia (M0), adult acute myeloblastic leukemia without maturation (M1), adult acute myeloblastic leukemia with maturation (M2), adult acute myelomonocytic leukemia (M4), adult acute monoblastic leukemia (M5a), adult acute monocytic leukemia (M5b), adult erythroleukemia (M6a), adult pure erythroid leukemia (M6b), adult acute megakaryoblastic leukemia (M7), adult acute myeloid leukemia with 11q23 (MLL) abnormalities, adult acute myeloid leukemia with del(5q), adult acute myeloid leukemia with inv(16)(p13;q22), adult acute myeloid leukemia with t(16;16)(p13;q22), adult acute myeloid leukemia with t(8;21)(q22;q22)
A Study of LY2157299 in Participants With Hepatocellular Carcinoma Mulcahy, Mary Frances
A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast Cancer Gradishar, William J 1st line MBC, MBC, hormone receptor positive, lapatinib, trastuzumab, HER2 positive, aromatase inhibitor
Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer Hayes, John P
NU 16H07: Phase II Trial of Pembrolizumab in Combination with ICE Salvage Chemotherapy for Relapsed/Refractory Hodgkin Lymphoma Winter, Jane Norma Hodgkin Lymphoma; Immunotherapy; , Pembrolizumab; , Keytruda; , Clinical trial, Research, Lymphoma, phase 2, relapse (cancer has come back); refractory (cancer has not responded)
A Phase II study of Plitidepsin in Patients with Relapsed or Refractory Angioimmunoblastic T-cell Lymphoma Pro, Barbara Lymphoma; Pitlidepsin; , relapse (cancer has come back); , refractory (cancer has not responded) ; Clinical trial; Research; T-Cell; Angioimmunoblastic; phase 2
Hydrogel Endovascular Aneurysm Treatment Trial Ansari, Sameer Ahmad treatment trial, cerebral aneurysm, randomized, coils, endovascular, HEAT, bare platinum, Hydrogel, Hydrocoil
A Trial Comparing Combined Spinal- Epidural Dosing Strategies for External Cephalic Version Chalifoux, Laurie Version, Pregnancy, Vaginal Delivery, Pain Control, Combined Spinal Epidural
A New Insertion Technique for Laryngeal Mask Airway Hu, LingQun Intubation, Airway, Laryngeal Mask Airway
Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML Altman, Jessica K
Radiation Therapy in Treating Patients With Extensive Stage Small Cell Lung Cancer Kruser, Timothy extensive stage small cell lung cancer
Registry for the Atopic Dermatitis Research Network Paller, Amy Registry, Atopic Dermatitis, Eczema Herpeticum, GWAS, Staphylococcus aureus
The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF) Mesulam, Marek-Marsel Intranasal insulin, Alzheimer's disease, Amnestic mild cognitive impairment, Dementia, Brain diseases, Memory problems, Mental disorders, Cognitive disorders
A Phase 1, Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of Orally Administered CA-170 in Patients with Advanced Tumors and Lymphomas Sosman, Jeffrey phase 1; advanced tumor; lymphoma; , immune system; oral drug;
NU 16H08: Phase II study of PET-directed frontline therapy with pembrolizumab and AVD for patients with classical Hodgkin lymphoma Winter, Jane Norma classical hodgkin lymphoma; immunotherapy; Pembrolizumab; Keytruda; Clinical trial; Research; phase 2
Prevention Strategy for Pre-Menopausal Women at High Risk for Development of Breast Cancer Khan, Seema Ahsan Ahsan
A Study of a Retroviral Replicating Vector Administered to Subjects With Recurrent Malignant Glioma Raizer, Jeffrey J glioma, glioblastoma, glioblastoma multiforme, Grade IV astrocytoma, brain cancer, recurrent glioblastoma, GBM, AA, AOD, anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma, malignant glioma, high grade glioma
Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery Hayes, John P stage IA breast cancer, stage IB breast cancer, stage II breast cancer, estrogen receptor-negative breast cancer, estrogen receptor-positive breast cancer, progesterone receptor-negative breast cancer, progesterone receptor-positive breast cancer, ductal breast carcinoma in situ
High Dose Lurasidone for Patients With Treatment Resistant Schizophrenia Meltzer, Herbert Schizophrenia, Refractory, Treatment resistant, Lurasidone
Targeted Intraoperative Radiotherapy United States (TARGIT-US) Registry Trial Donnelly, Eric Disease-Free Survival, Female, Humans, Intraoperative Care, Mastectomy Segmental, Middle Aged, Neoplasm Recurrence Local, Radiotherapy Dosage, Radiotherapy Adjuvant
Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis Brieva, Joaquin C videocapillaroscopy, psoriasis, systemic agent
Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas Raizer, Jeffrey J Information Not Provided
Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors Kumthekar, Priya
Improving Hypertension Using a Smartphone-Enabled Personal Control Program: Persell, Stephen D
Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies Cuttica, Michael J pulmonary arterial hypertension, PAH, treprostinil sodium, Tyvaso, inhalation, Ventavis, iloprost, prostacyclin, epoprostenol sodium, Flolan, Veletri, subcutaneous and intravenous prostacyclin analogue, Remodulin, oral ERA, bosentan, Tracleer, ambrisentan, Letairis, oral PDE5 inhibitors, sildenafil, Revatio, tadalafil, Adcirca, Opsumit, macitentan, Adempas, riociguat, Orenitram, oral treprostinil
Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML) Frankfurt, Olga AML, relapsed, refractory
A Study of DFRF4539A in Patients With Relapsed or Refractory Multiple Myeloma Singhal, Seema
Escalating Dose Study in Subjects With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia Ma, Shuo non-hodgkin's lymphoma, lymphoma, leukemia, chronic lymphocytic leukemia, b-cell malignancies, Btk inhibitor, Phase 1b, Avila Therapeutics, Waldenstrom Macroglobulinemia
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery Chandra, Sunandana
OTO-104 for the Treatment of Meniere's Disease Micco, Alan G Meniere's Disease, Vertigo, Definitive vertigo, Vertigo episodes, Vertigo frequency, Tinnitus, Hearing loss, Aural fullness
Maternal and Neurodevelopmental Outcomes of in Utero Antiepileptic Drug (AED) Exposure Gerard, Elizabeth Erway Epilepsy, Pregnancy
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer Gradishar, William J
Ruxolitinib (INCB018424) in Subjects With Primary Myelofibrosis, Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis Stein, Brady Lee PMF, PPV-MF, PET-MF
Randomized Phase II Trial of Trastuzumab or EVEROLIMUS in Hormone-refractory Metastatic Breast Cancer Santa-Maria, Cesar Breast Cancer
Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery Sejpal, Samir stage I salivary gland cancer, stage II salivary gland cancer, stage III salivary gland cancer, high-grade salivary gland mucoepidermoid carcinoma, salivary gland adenocarcinoma, stage IVA salivary gland cancer, stage IVB salivary gland cancer, stage IVC salivary gland cancer
The INSPIRE Study: In Vivo Study of Probable Benefit of the Neuro-Spinal Scaffold™ for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury Dahdaleh, Nader spinal cord injury, back injury, complete spinal cord injury, thoracic injury, traumatic injury, paraplegia
Electronic Patient Reported Symptom Assessment Berry, Emily Advanced Care Planning, Palliative Care, Women
A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer Carneiro Filho, Benedito cancer, immunotherapy, immunochemotherapy, combinational therapy, targeted, metastatic, muscle invasive, interleukin-2, cisplatin, gemcitabine, antitumor, TCR, T-cell receptor, p53, p53 gene, p53 tumor supressor protein, urothelial cancer, bladder cancer, renal pelvis cancer, ureters cancer, urethra cancer, HLA-A2 positive, HLA-A*0201/p53 aa264-272, HLA complex, Muscle Invasive or Metastatic
Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer Mittal, Bharat B stage III squamous cell carcinoma of the oropharynx, stage IV squamous cell carcinoma of the oropharynx, human papilloma virus infection
Evaluation of RenalGuard® System to Reduce the Incidence of Contrast Induced Nephropathy in At-Risk Patients Davidson, Charles J
Clinical Study of BYM338 for the Treatment of Unintentional Weight Loss in Patients With Cancer of the Lung or the Pancreas Mulcahy, Mary Frances Wasting syndrome, emaciation, lung cancer, adenocarcinoma, pancreatic cancer
Ipilimumab and Gemcitabine Hydrochloride in Treating Patients With Stage III-IV or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery Mulcahy, Mary Frances
Pathophysiology of Post Amputation Pain Harden, Robert N
Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy Wunderink, Richard G sepsis
Home-Based Symptom Management Via Reflexology for Breast Cancer Patients Victorson, David E Breast Cancer, Reflexology, Complementary
Microbiomes of Pelvic Pain Klumpp, David
Bortezomib, Ifosfamide, Carboplatin, and Etoposide, With or Without Rituximab, in Treating Patients With Relapsed or Refractory AIDS-Related Non-Hodgkin Lymphoma Petrich, Adam AIDS-related diffuse large cell lymphoma, AIDS-related diffuse mixed cell lymphoma, AIDS-related diffuse small cleaved cell lymphoma, AIDS-related immunoblastic large cell lymphoma, AIDS-related lymphoblastic lymphoma, AIDS-related peripheral/systemic lymphoma, AIDS-related primary CNS lymphoma, AIDS-related small noncleaved cell lymphoma
TK008: Efficacy Study on the Strategy of Herpes Simplex Virus Thymidine Kinase (HSV-Tk) Donor Lymphocytes to Treat Patients With High Risk Acute Leukemia Mehta, Jayesh high risk acute leukemia, HSV-TK, Haploidentical HCT, GvHD, GvL, Immunoreconstitution
Hormone Therapy in Treating Men With Stage IV Prostate Cancer Benson III, Al B adenocarcinoma of the prostate, stage IV prostate cancer, recurrent prostate cancer
Motivational Interviewing and Physical Activity in Parkinson’s Disease Ehrlich-Jones, Linda S Parkinson's Disease, Parkinson's, Exercise, Physical Activity
Home sleep and circadian phase: mediators of racial disparities in diabetes risk Knutson, Kristen sleep, circadian rhythms, diabetes, cardiovascular disease
A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma Winter, Jane Norma Lymphoma, Large B-Cell, Diffuse, Antigens, CD30, Antibody-Drug Conjugate, Antibodies, Monoclonal, Lymphoma, Non-Hodgkin, Monomethyl auristatin E, Drug Therapy, Immunotherapy, Hematologic Diseases, Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell
A Phase 3 Single Center Study of Islet Transplantation in Non-uremic Diabetic Patients Luo, Xunrong Diabetes, Islet, Pancreas, Hypoglycemia, T1D, Transplant
Efficacy Evaluation of TheraSphere Following Failed First Line Chemotherapy in Metastatic Colorectal Cancer Mulcahy, Mary Frances
A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV) Grobman, William A Perinatology, Cytomegalovirus immune globulin, Cytogam, CMVIG infusions, primary CMV infection in pregnancy
Bortezomib and Romidepsin in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Indolent B-cell Lymphoma, Peripheral T-cell Lymphoma or Cutaneous T-Cell Lymphoma Ma, Shuo refractory chronic lymphocytic leukemia, stage I chronic lymphocytic leukemia, stage II chronic lymphocytic leukemia, stage III chronic lymphocytic leukemia, stage IV chronic lymphocytic leukemia, recurrent small lymphocytic lymphoma, contiguous stage II small lymphocytic lymphoma, noncontiguous stage II small lymphocytic lymphoma, stage I small lymphocytic lymphoma, stage III small lymphocytic lymphoma, stage IV small lymphocytic lymphoma, adult nasal type extranodal NK/T-cell lymphoma, anaplastic large cell lymphoma, angioimmunoblastic T-cell lymphoma, extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, hepatosplenic T-cell lymphoma, nodal marginal zone B-cell lymphoma, peripheral T-cell lymphoma
Sleep Disturbance and Metabolic Syndrome Zee, Phyllis C overweight, high blood pressure, high blood sugar, trouble falling or staying asleep, poor sleep quality
Cardiometabolic outcomes with light exposure during sleep Zee, Phyllis C
Circadian rhythms and epilepsy: a prospective study Zee, Phyllis C Generalized seizures and focal seizures, sleep-wake and circadian rhythm patterns in patients with epilepsy
Effect of sleeping place on objective and subjective sleep quality Zee, Phyllis C female, good sleepers, 40 and older
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Active Comparator, Parallel-Group Study of the Efficacy and Safety of Lemborexant in subjects 55 Years and Older with Insomnia Disorder Abbott, Sabra Trouble falling asleep, Trouble staying asleep, Insomnia, Age 55 or older
Annular ReduCtion for Transcatheter Treatment of Insufficient Mitral ValvE (ACTIVE): A prospective, multicenter, randomized, controlled pivotal trial to assess transcatheter mitral valve repair with Edwards Cardioband System and guideline directed medical therapy (GDMT) compared to GDMT alone in patients with functional mitral regurgitation (FMR) and heart failure. Davidson, Charles J Mitral Valve, mitral regurgiation, Heart Valve, Valve Disease , functional MR, Cardioband, transcatheter, TMVR, mitral valve repair, MVR
Pazopanib Hydrochloride in Treating Patients With Advanced Angiosarcoma Agulnik, Mark
The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury Wunderink, Richard G rhACE2, Acute Respiratory Distress Syndrome (ARDS), Acute Lung Injury, GSK2586881, critical care
Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma Raizer, Jeffrey J neurotoxicity, chemotherapeutic agent toxicity, radiation toxicity, cognitive/functional effects, primary central nervous system non-Hodgkin lymphoma
Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer Donnelly, Eric
Double-blind, Randomized, Placebo-controlled Phase 2 Safety and Efficacy Trial of MultiStem in Adults with Ischemic Stroke Bernstein, Richard A
Light Phase Response Curve in Delayed Sleep Wake Phase Disorder Abbott, Sabra sleep, circadian, delayed sleep-wake phase disorder
A multicenter, international, open-label, safety study of ND0612, a solution of levodopa/carbidopa delivered via a pump system as a continuous subcutaneous infusion in subjects with advanced Parkinson's Disease (BeyoND) Simuni, Tatyana
Multicenter, randomized, double-blind, placebo controlled study to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of GZ/SAR402671 in patients with early-stage Parkinson’s disease carrying a GBA mutation or other pre-specified variant. Simuni, Tatyana
A Study to Show That Treatment With Denosumab is as Good as Treatment With Risedronate in Subjects Who Are Starting to Take or Currently Taking Glucocorticoids. Schnitzer, Thomas J GIOP, Glucocorticoid, osteporosis, denosumab, BMD, Bone Mineral Density
Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas Petrich, Adam
GLORIA-AF Registry Program - Second and Third Phases Bernstein, Richard A
S1106 Rituximab With Combination Chemotherapy or Bendamustine Hydrochloride Followed by Consolidation Chemotherapy and Stem Cell Transplantation in Older Patients With Previously Untreated Mantle Cell Lymphoma Winter, Jane Norma contiguous stage II mantle cell lymphoma, noncontiguous stage II mantle cell lymphoma, stage III mantle cell lymphoma, stage IV mantle cell lymphoma
Stepped Telemental Health Care Intervention for Depression Mohr, David C Depression, Cognitive Behavioral Therapy, Internet, Telemedicine
Minimally Invasive Groin Dissection for Melanoma Bilimoria, Karl Melanoma, Lymph Nodes, Lymph Node Dissection, Minimally invasive
Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence Santa-Maria, Cesar HER2, low or intermediate, breast cancer, node-positive tumors
A Dose Escalation Trial of PR610 Treating Patients With Solid Tumors Patel, Jyoti D D NSCLC, non-small cell lung cancer, non-squamous, non-small cell lung cancer, solid tumors, lung cancer
PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy Benson III, Al B adenocarcinoma of the gastroesophageal junction, adenocarcinoma of the esophagus, stage IB esophageal cancer, stage IIA esophageal cancer, stage IIB esophageal cancer, stage IIIA esophageal cancer, stage IIIB esophageal cancer, stage IIIC esophageal cancer
S1001 PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma Kaplan, Jason stage I adult diffuse large cell lymphoma, contiguous stage II adult diffuse large cell lymphoma, noncontiguous stage II adult diffuse large cell lymphoma, stage III adult diffuse large cell lymphoma, stage IV adult diffuse large cell lymphoma
Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation Anderson, Allen
Rhythm Evaluation for AntiCoagulaTion With COntinuous Monitoring Chicos, Alexandru Bogdan atrial fibrillation, reveal xt, oral anticoagulation, dabigatran, rivaroxaban, apixaban
Lacosamide for Seizure Prophylaxis in High-Grade Gliomas Raizer, Jeffrey J Brain cancer, Central nervous system, Seizure prophylaxis, High-Grade Gliomas, HGG, Supratentorial high-grade glioma, Malignant glioma, Lacosamide, Vimpat, Placebo, Sugar pill
Efficacy of Gralise® for Chronic Pelvic Pain Harden, Robert N Pelvic Pain, Chronic Pelvic Pain, Irritable Bowel Syndrome, IBS, Ulcerative Colitis, UC, Interstitial Cystitis, IC, Prostatitis, Pain
A Study of Onartuzumab (MetMAb) Versus Placebo in Combination With Paclitaxel Plus Platinum in Patients With Squamous Non-Small Cell Lung Cancer Patel, Jyoti D D
Safety and Efficacy Study of Dronabinol to Treat Obstructive Sleep Apnea Zee, Phyllis C
Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer Agulnik, Mark
A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With Crizotinib Patel, Jyoti D D Non-small cell lung cancer
Sorafenib Tosylate With or Without Everolimus in Treating Patients With Advanced, Radioactive Iodine Refractory Hurthle Cell Thyroid Cancer Matsangou, Maria
3D Echocardiographic and Doppler Data as a Comparison to Cardiac Magnetic Resonance (CMR) Imaging Thomas, James
A Phase 1 Study of MEDI6383 in Adult Subjects With Select Advanced Solid Tumors Chae, Young Kwang Urothelial bladder cancer, colorectal adenocarcinoma, non-small cell lung cancer, squamous cell carcinoma of the head and neck
Targeting Siglecs in Disease supported by NIH Grant R01 AI072265 Targeting Siglec-8/-F to treat eosinophil and mast cell related disorders and P01 HL107151 Glycobiology of Inflammatory Lung Diseases: Project 1 and U19 AI136443 Using Siglecs and Their Ligands to Treat Allergic Diseases: Project 1 and Core B. Bochner, Bruce
Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary Peritoneal Cancer Pineda, Mario High Risk
A Phase 1b Study Evaluating the Safety and Tolerability of ABT-199 in Combination With Rituximab in Subjects With Relapsed Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Ma, Shuo Tolerability, Chronic Lymphocytic Leukemia, Efficacy, Rituximab, Safety, Maximum Tolerated Dose, Preliminary, ABT-199, Cancer, Pharmacokinetics, Small Lymphocytic Lymphoma
A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL Altman, Jessica K Marqibo, HALLMARQ, leukemia, front-line, ALL, acute lymphoblastic leukemia
Improving Psychosocial Quality of Life in Women With Advanced Breast Cancer Wolf, Michael Metastatic, Quality of life, Decision making
A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Patients With CD30-Positive Cutaneous T-Cell Lymphoma Pro, Barbara
Study of Cabozantinib (XL184) Versus Mitoxantrone Plus Prednisone in Men With Previously Treated Symptomatic Castration-resistant Prostate Cancer Kuzel, Timothy Michael prostate cancer, castration resistant prostate cancer, bone pain, CRPC
Bortezomib, Rituximab, and Dexamethasone With or Without Temsirolimus in Treating Patients With Untreated or Relapsed Waldenstrom Macroglobulinemia or Relapsed or Refractory Mantle Cell or Follicular Lymphoma Ma, Shuo
Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall Donnelly, Eric Breast Cancer, Recurrent Chest Wall Cancer, Loco-regional Recurrent Breast Cancer, Breast Cancer Recurrence at the Chest Wall
HepaSphere/Quadrasphere Microspheres for Delivery of Doxorubicin for the Treatment of Hepatocellular Cancer Lewandowski, Robert J Hepatocellular carcinoma, TACE, HepaSphere Microspheres, QuadraSphere Microspheres, Doxorubicin
BI 836858 Dose Escalation in Refractory or Relapsed Acute Myeloid Leukemia Altman, Jessica K
Methotrexate or Dactinomycin in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Shahabi, Shohreh
Early Intervention in Cystic Fibrosis Exacerbation Jain, Manu telemedicine, spirometer, CF, pulmonary, home monitoring
Extended Varenicline Treatment for Smoking Among Cancer Patients Hitsman, Brian L Smoking cessation, Nicotine dependence, Varenicline, Chantix, Cancer
Response-Based Therapy Assessed By PET Scan in Treating Patients With Bulky Stage I and Stage II Classical Hodgkin Lymphoma Pro, Barbara stage I adult Hodgkin lymphoma, stage II adult Hodgkin lymphoma, adult favorable prognosis Hodgkin lymphoma, adult lymphocyte depletion Hodgkin lymphoma, adult lymphocyte predominant Hodgkin lymphoma, adult mixed cellularity Hodgkin lymphoma, adult nodular sclerosis Hodgkin lymphoma, adult unfavorable prognosis Hodgkin lymphoma
Clinical Trials to Reduce the Risk of Antimicrobial Resistance Wunderink, Richard G gram negative pathogens, Pseudomonas aeruginosa, Acinetobacter, HCAP, VABP, HABP
Lidocaine and Prevention of Chronic Pain De Oliveira, Gildasio S Surgery, Breast, Pain, Chronic Pain, Lidocaine, Anesthesia, Gynecologic, Urologic
The Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide or In Combination With Carboplatin and Paclitaxel Versus Placebo in Subjects With BRCA1 and BRCA2 Mutation and Metastatic Breast Cancer Gradishar, William J Temodal, ABT-888, Carboplatin, TMZ, Temodar, PARP, temozolomide, Paclitaxel, Recurrent breast cancer, Breast cancer, Metastatic breast cancer, BRCA2 mutation carrier, BRCA1 mutation carrier, veliparib, Locally recurrent
Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MF Stein, Brady Lee Keywords provided by NS Pharma, Inc.:, JAK2 kinase inhibitor, NS-018, Myeloproliferative Neoplasms, Primary Myelofibrosis, post-Polycythemia Vera Myelofibrosis, post-Essential Thrombocythemia Myelofibrosis, Additional relevant MeSH terms:, Bone Marrow Diseases, Hematologic Diseases, Polycythemia Vera, Thrombocythemia, Essential, PMF, post-PV MF, post-ET MF
Study of KW-0761 Versus Vorinostat in Relapsed/Refractory CTCL Pro, Barbara Cutaneous T-Cell Lymphoma (CTCL), myocis fungoides (MF), Sezary Syndrome (SS)
Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma Winter, Jane Norma neurotoxicity, therapy-related toxicity, contiguous stage II mantle cell lymphoma, noncontiguous stage II mantle cell lymphoma, stage I mantle cell lymphoma, stage III mantle cell lymphoma, stage IV mantle cell lymphoma
ANTLER Pilot Intervention Ramsey-Goldman, Rosalind
Genome Research in African American Scleroderma Patients (GRASP) Varga, John systemic sclerosis, scleroderma, genetics, DNA, genes, African Americans
A Study Comparing Treatment With 177Lu-DOTA0-Tyr3-Octreotate to Octreotide LAR in Patients With Inoperable, Progressive, Somatostatin Receptor Positive Midgut Carcinoid Tumours Benson III, Al B Neuroendocrine tumour, 177Lu-Dota0-Tyr3-octreotate
A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Altman, Jessica K Hedgehog Inhibitor, Acute Myeloid Leukemia, Myelodysplastic syndrome, Intensive chemotherapy, LDAC
A Clinical Study Conducted in Multiple Centers Comparing Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Subjects With Brain Metastases From Non Small Cell Lung Cancer (NSCLC) Raizer, Jeffrey J
Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study Kalhan, Ravi COPD, RePneu
An Observational Study of Hepatitis C Virus in Pregnancy Grobman, William A observational study, 2 year child follow-up, known HCV positive
Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Frankfurt, Olga
Safety and Efficacy Study of Gevokizumab to Treat Active Non-infectious Uveitis Goldstein, Debra Uveitis, Non-infectious Uveitis, Intermediate Uveitis, Posterior Uveitis, Panuveitis
Ultrasound-guided Adductor Canal Block for Total Knee Replacement Nader, Antoun
Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma Kircher, Sheetal Advanced HCC, Temsirolimus, TORISEL, Sorafenib
Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Goldstein, Debra
Dose-Escalation Trial of Carfilzomib With and Without Romidepsin in Cutaneous T-Cell Lymphoma Pro, Barbara
Cabergoline in Metastatic Breast Cancer Santa-Maria, Cesar
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Agulnik, Mark
Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma Raizer, Jeffrey J Malignant glioma, Recurrent Glioblastoma, Glioblastoma multiforme, Gliosarcoma, Anaplastic astrocytoma, Anaplastic oligodendroglioma, Anaplastic oligoastrocytoma, Vorinostat, SAHA, Suberoylanilide Hydroxamic Acid, MSK-390, Zolinza, Bevacizumab, Avastin, Anti-VEGF monoclonal antibody, rhuMAb-VEGF
Study of Vitamin D in Untreated Metastatic Colorectal Cancer Kircher, Sheetal previously untreated
Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) Agulnik, Mark GEMCITABINE, GW786034 (PAZOPANIB), TAXOTERE (DOCETAXEL), 11-104
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas Raizer, Jeffrey J Malignant glioma, Glioblastoma multiforme, GBM, Gliosarcoma, GS, Anaplastic astrocytoma, AA, Anaplastic oligodendroglioma, AO, Anaplastic mixed oligoastrocytoma, AMO, Malignant astrocytoma, Recurrent high-grade gliomas, recurrent intracranial malignant glioma, Malignant astrocytoma not otherwise specified, NOS, Everolimus, Afinitor, RAD001, Sorafenib, Nexavar, BAY 43-9006
Phase IIb Study of Dasatinib Versus Imatinib in Patients With CML-CP Who Have Not Achieved an Early Optimal Response to Imatinib Frankfurt, Olga
A Study to Investigate the Efficacy and Safety of Bendamustine Compared With Bendamustine+RO5072759 (GA101) in Patients With Rituximab-Refractory, Indolent Non-Hodgkin's Lymphoma (GADOLIN) Ma, Shuo follicular, follicular lymphoma
Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma Raizer, Jeffrey J EGFRvIII, Glioblastoma, Small cell, Giant cell, Gliosarcoma, oligodendroglial, Brain Cancer, Brain Tumor, radiotherapy, chemoradiation, Tumor, temozolomide, EGFR variant III
Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia Frankfurt, Olga AML, Acute Myeloid Leukemia, high risk AML, secondary AML, AML in elderly
Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson's Disease Simuni, Tatyana Parkinson's Disease, Cognition, Rasagiline
Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese Neff, Lisa M glycemic control, type 2 diabetes, device, obese
Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma Kaplan, Jason
Effects of Tolvaptan in Healthy Adults Robertson, Gary L Tolvaptan, Aquaretic Efficacy
A Phase 2b/3, Double-Blind, Randomized, Placebo Controlled, Multicenter Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury Cybulski, George R neck injury, spinal cord injury, complete spinal cord injury, neck trauma, quadraplegia
A Phase II Study of Tivozanib in Patients With Metastatic and Non-resectable Soft Tissue Sarcomas Agulnik, Mark
Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer Donnelly, Eric gastrointestinal complications, perioperative/postoperative complications, radiation toxicity, urinary complications, urinary tract toxicity, endometrial clear cell carcinoma, endometrial papillary serous carcinoma, stage IA endometrial carcinoma, stage IB endometrial carcinoma, stage II endometrial carcinoma, stage IIIA endometrial carcinoma, stage IIIB endometrial carcinoma, stage IIIC endometrial carcinoma, endometrial adenocarcinoma, cervical adenocarcinoma, stage IB cervical cancer, stage IIA cervical cancer, stage IIB cervical cancer
Cetuximab With or Without Tivantinib in Treating Patients With Head and Neck Cancer That Is Recurrent, Metastatic, or Cannot Be Removed By Surgery Agulnik, Mark
Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver Cancer Kulik, Laura M
Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Agulnik, Mark
Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM) Mohr, David C Android, Smartphone Apps, Depression, Anxiety
Oral CDB-4124 vs. Placebo in Stage I-II Primary Breast Cancer Khan, Seema Ahsan Ahsan
Safety and Efficacy Study of Gevokizumab to Treat Non-infectious Uveitis Controlled With Systemic Treatment Goldstein, Debra Uveitis, Non-infectious Uveitis, Intermediate Uveitis, Posterior Uveitis, Panuveitis
SRL (Sirolimus) Withdrawal Levitsky, Josh Liver Transplant, Sirolimus, Rapamune, Immunosuppressant Therapy, Withdrawal
S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer Benson III, Al B recurrent esophageal cancer, stage IV esophageal cancer, recurrent gastric cancer, stage IV gastric cancer, adenocarcinoma of the gastroesophageal junction, stage IIIB gastric cancer, stage IIIC gastric cancer, stage IIIB esophageal cancer, stage IIIC esophageal cancer, adenocarcinoma of the esophagus, adenocarcinoma of the stomach
SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC) Mulcahy, Mary Frances
Tri-weekly Cisplatin Based Chemoradiation in Locally Advanced Cervical Cancer Small Jr, William Small Cervical cancer, Concurrent chemoradiation, Cisplatin
Impact of autoimmunity on olfaction in patients with chronic sinusitis with nasal polyposis (CRSwNP) Tan, Bruce Kuang-Huay K
International GBS Outcome Study (IGOS) A prospective INC study on clinical and biological predictors of disease course and outcome in GBS Ajroud-Driss, Senda
A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia Frankfurt, Olga
KW 0761 or Investigator's Choice in Subjects With Previously Treated Adult T-cell Leukemia-Lymphoma (ATL) Petrich, Adam Adult T cell Leukemia-Lymphoma (ATL)
Ipilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By Surgery Kuzel, Timothy Michael
Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma Kumthekar, Priya
Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery Berry, Emily
A Trial of an Oral Nutritional Supplement in Older Hospitalized Patients Wunderink, Richard G
Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia Wunderink, Richard G Gram-negative pneumonia, Intubation, Mechanical ventilation, Amikacin
Study to Evaluate the Safety and Efficacy of Dermal Injections of JVS-100 Given to Adults Receiving Median Sternotomy McCarthy, Patrick M Cicatrix, Wound healing
Cediranib Maleate With or Without Lenalidomide in Treating Patients With Thyroid Cancer Agulnik, Mark
Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-naïve Patients With Progressive Metastatic Castration-resistant Prostate Cancer Hussain, Maha MDX-010 (Ipilimumab), ABIRATERONE ACETATE (CB 7630), PREDNISONE, Immunotherapy-naïve, castration resistant prostate cancer (CRPC), 12-120
Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery McCarthy, Robert J
Pilot study on the effect of endometrial injury in patients undergoing in vitro fertilization (IVF) Barnes, Randall
Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator Frankfurt, Olga Glivec/Gleevec, CML, GIST, Imatinib mesylate
A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Inactive Non-infectious Intermediate-, Posterior-, or Pan-uveitis Fawzi, Amani
FTC/RPV/TDF on T-Cell Activation, CD4 Cell Count, Inflammatory Biomarkers and Viral Reservoir Taiwo, Babafemi O
The Genetics of Prostate Cancer in Active Surveillance Kundu, Shilajit D prostate cancer, active surveillance, PSA
3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy Kuzel, Timothy Michael ABIRATERONE ACETATE (CB 7630), DEGARELIX, PREDNISONE, 12-187
Northwestern Chronic Rhinosinusitis (CRS) Subject Registry Tan, Bruce Kuang-Huay K
Safety and Efficacy of LEE011 and LGX818 in Patients With BRAF Mutant Melanoma. Kuzel, Timothy Michael Open-label dose escalation; BRAF inhibitor; LEE011; CDK4/6; LGX818; RAF kinase inhibitor; metastatic melanoma; BRAF; V600
Safety and Efficacy of Roflumilast and Pioglitazone in Treating Adults With Nonalcoholic SteatoHepatitis Rinella, Mary Eugenia Drug therapy
OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone MacVicar, Gary R OGX-427, Abiraterone Acetate
Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery Bloch, Orin
BRAF Inhibitor, Vemurafenib, in Patients With Relapsed or Refractory Hairy Cell Leukemia Altman, Jessica K VEMURAFENIB (PLX4032 or R05185426), BRAF Inhibitor, 12-200
A Prospective, Multi-Center Trial Evaluating the Effectiveness of the V.A.C. Ulta Negative Pressure Wound Therapy System With V.A.C. VeraFlo Dressing System in Operatively Debrided Wounds Galiano, Robert D
Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or In Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer Patel, Jyoti D D
Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia Altman, Jessica K
Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients Altman, Jessica K AML, Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer or Metastatic Large Cell Neuroendocrine Non-Small Cell Lung Cancer Patel, Jyoti D D
Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy Kumthekar, Priya
Evaluate the Safety and Efficacy of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis Bhorade, Sangeeta Idiopathic Pulmonary Fibrosis, IPF, Idiopathic Interstitial Pneumonia, Interstitial Lung Disease, Lung Fibrosis
Phase 2 Study of Bevacizumab in Children and Young Adults With Neurofibromatosis 2 and Progressive Vestibular Schwannomas Raizer, Jeffrey J Neurofibromatosis Type 2, Progressive Vestibular Schwannomas
A First-in-Human Phase 1 and Expanded Cohort Study of EPZ-5676 in Advanced Hematologic Malignancies, Including Acute Leukemia With Rearrangement of the MLL Gene Altman, Jessica K Leukemia, Advanced hematologic malignancies, Epizyme, Phase 1, Mixed Lineage Leukemia (MLL)
A Phase 2 Study to See if Simtuzumab (GS-6624) is Safe and Works in Idiopathic Pulmonary Fibrosis (IPF) Raj, Rishi Idiopathic, Pulmonary, Fibrosis, IPF
A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma Raizer, Jeffrey J glioblastoma, GBM
Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study Yilmaz, Meltem QOR-40, Pain, Hypoxia, Gastric Surgery, Obesity, Ketamine
Prostatic Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia (BPH) Salem, Riad Prostate Artery Embolization, PAE, Benign Prostatic Hyperplasia, BPH, Lower Urinary Tract Symptoms, LUTS
CNDO-109-AANK for AML in First Complete Remission (CR1) Frankfurt, Olga Acute Myeloid Leukemia, High Risk Relapse, Complete Remission, Allogeneic Natural Killer Cells
Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia in Complete Remission Frankfurt, Olga Maintenance therapy, AML, Acute Myeloid Leukemia, oral Azacitidine, best supportive care, complete remission
Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer Chae, Young Kwang Non-small Cell Lung Cancer, Vaccine Therapy, Immunotherapy, Second line therapy, Progressive, Relapsed
Pregnant Women Taking Lamictal for Bipolar Disorder Clark, Crystal pregnant, bipolar, lamotrigine, lamictal, women, female
SYMPHONY: A Study of Macitentan in Pulmonary Arterial Hypertension to Validate the PAH-SYMPACT Cuttica, Michael J Pulmonary Arterial Hypertension
Evaluation of Centration of Intraocular Lens With Two Settings for Capsulorhexis With Femtosecond Laser Basti, Surendra capsulorhexis, IOL centration
Methotrexate in Induction and Maintenance of Steroid Free Remission in Ulcerative Colitis Hanauer, Stephen
A Study of PCI-32765 (Ibrutinib) in Patients With Refractory Follicular Lymphoma Petrich, Adam Lymphoma, Refractory follicular lymphoma, Chemoimmunotherapy-resistant follicular lymphoma, PCI-32765, Ibrutinib
A Phase 2, Randomized Dose-ranging Study to Evaluate the Efficacy of Tralokinumab in Adults With Idiopathic Pulmonary Fibrosis Raj, Rishi
A Prospective, Double-masked, Placebo Controlled Comparison of Topical 0.15% Ganciclovir Gel (Zirgan®) Versus 0.3% Hypromellose Gel (Genteal Gel®; Placebo) for the Treatment of Herpes Zoster Keratitis While on Oral Anti-viral Treatment Feder, Robert S
Epigenetic Markers of Bladder Cancer Progression Meeks, Joshua J bladder cancer, urothelial carcinoma
Vitamin D and Type 2 Diabetes Study Neff, Lisa M Prediabetes, Vitamin D
Study of Zevalin Versus Observation in Patients at Least 60 Yrs Old With Newly Diagnosed Diffuse Large B-cell Lymphoma in PET-negative Complete Remission After R-CHOP or R-CHOP-like Therapy Winter, Jane Norma
Dose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in Patients With Relapsed or Refractory Acute Myeloid Leukemia Altman, Jessica K Acute Myeloid Leukemia, ASP2215
An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD Singhal, Seema Multiple myeloma, Daratumumab, Proteasome inhibitor, Immunomodulatory drug, IMiD
Open-Label Study Evaluating Dasatinib Therapy Discontinuation in Patients With Chronic Phase Chronic Myeloid Leukemia With Stable Complete Molecular Response Altman, Jessica K
Phase 1/2, Open-label, Dose-escalation Study of ISIS-STAT3Rx, Administered to Patients With Advanced Cancers Petrich, Adam Advanced Cancers, DLBCL, Advanced Lymphoma
Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme Kumthekar, Priya GBM
A Study of the Efficacy of ABT-199 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia With the 17p Deletion Ma, Shuo Chronic Lymphocytic Leukemia, 17 p Deletion
A Study of Vismodegib With Surgery in Patients With Previously Untreated Basal Cell Carcinoma Yoo, Simon S
A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma Carneiro Filho, Benedito renal cell cancer, kidney, vascular endothelial growth factor receptor 2 (VEGFR2), tyrosine kinase inhibitor, hepatocyte growth factor receptor protein (MET), von Hippel-Lindau gene
Vaccine Therapy for Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Ma, Shuo Cancer vaccine, Chronic lymphocytic leukemia, CLL, Autologous vaccine, B cell leukemia
Standard or Comprehensive Radiation Therapy in Treating Patients With Early-Stage Breast Cancer Previously Treated With Chemotherapy and Surgery Donnelly, Eric
Civacir® Polyclonal Immune Globulin (IgG) to Prevent Hepatitis C Virus (HCV) Recurrence in Liver Transplant Patients. Kulik, Laura M HCV Liver Transplant Immunoglobulin PCR SVR
A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes Molitch, Mark E Kidney Diseases, Diabetic Nephropathies, Diabetes Mellitus, Diabetes Complications, Uric acid, Allopurinol, Glomerular filtration rate, Coronary artery disease
A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma Petrich, Adam Mantle cell lymphoma, Ibrutinib, Bruton's tyrosine kinase inhibitor, Bendamustine hydrochloride, Rituximab
Phase 3 Frontline Therapy Trial in Patients With Advanced Classical Hodgkin Lymphoma Pro, Barbara Hodgkin Lymphoma, Hodgkin's Lymphoma, Antibody, Monoclonal, Antibody-Drug Conjugate, Antigens, CD-30, Immunotherapy, Lymphoma, Lymphoma, Classical
Safety and Tolerability of Pirfenidone in Patients With Systemic Sclerosis−Related Interstitial Lung Disease (SSc-ILD) (LOTUSS) Dematte D'Amico, Jane E pirfenidone, SSc-ILD, scleroderma, systemic sclerosis, interstitial lung disease
Pazopanib Hydrochloride in Treating Patients With Progressive Carcinoid Tumors Benson III, Al B
Evaluation of operative versus non-operative management of common hind foot disorders Kadakia, Anish
Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer Gradishar, William J metastatic breast cancer, locally advanced breast cancer, HER2-, ER+, everolimus, Afinitor
Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast Cancer Gradishar, William J breast cancer, triple negative, androgen receptor positive
Biomarkers of Inflammation in Perinatal Depression in Women Undergoing Scheduled Cesarean Delivery Wisner, Katherine
Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Agulnik, Mark SCCHN, HNSCC
Safety Study of Intratumoral Injection of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies Jain, Sarika Phase 1, Metastatic Disease, Solid Tumor, Malignancy, Metastases, Clinical Trial, Hypoxia, Necrosis, Intratumoral, Locally advanced cancer, Immunotherapy, Sarcoma, Chordoma, Bacteriolytic
Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell Lymphoma Kaplan, Jason CC-122, CC-223, CC-292, Rituximab, Lymphoma, Diffuse Large B-Cell Lymphoma
Phase 3 Gene Therapy for Painful Diabetic Neuropathy Ajroud-Driss, Senda diabetic, neuropathy, shooting pain, burning pain, pins and needles pain, foot pain, ViroMed
[SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES] Bernstein, Richard A Acute ischaemic stroke., Transient ischaemic attack.
Warren Wright Adolescent Center Study #1 Breiter, Hans
Brain imaging-based strategies for treating urological chronic pelvic pain syndrome (UCPPS) pain Apkarian, Apkar
The effects of capsinoids on brown adipose tissue recruitment and activation in obesity Neff, Lisa M weight loss, brown fat
Analgesic Benefits of Genicular Nerve Blocks of the Posterior Knee for Patients Undergoing Anterior Cruciate Ligament (ACL) Reconstruction Rahangdale, Rohit Y Anterior cruciate ligament reconstruction
Rituximab and Combination Chemotherapy With or Without Lenalidomide in Treating Patients With Newly Diagnosed Stage II-IV Diffuse Large B Cell Lymphoma Kaplan, Jason
Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) Ganger, Daniel R hepatic encephalopathy, hyperammonemia, cirrhosis, ornithine phenylacetate, OCR-002
Study of Two Doses of MK-3475 (Pembrolizumab) Versus Docetaxel in Previously-Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010) Chae, Young Kwang
Oxytocin and Pain Sensitivity and Threshold Walega, David R Pain, Oxytocin
First-line Antimetabolites as Steroid-sparing Treatment Uveitis Pilot Trial Goldstein, Debra uveitis, antimetabolite, immunosuppressive, clinical trial
Tranversus Abdominis Plane (TAP) Block vs. Systemic Lidocaine: Effects on Recovery After Outpatient Gynecological Laparoscopy Rodes, Meghan Anesthesiology, Pain, TAP block, Gynecology, Postoperative, Analgesia
Progel Vascular Sealant Malaisrie, S Chris Chris Aorta, Aortic, Reconstruction, CABG, Bypass
A Phase 2 Study of MPDL3280A (an Engineered Anti-PDL1 Antibody) in Patients With PD-L1 Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer - "BIRCH" Mohindra, Nisha
MEK162 for Patients With RAS/RAF/MEK Activated Tumors Chae, Young Kwang RAS, RAF, MEK, NF1, MEK162, signature, papillary thyroid, small intestine, bladder, esophagus, lung cancer, NSCLC, acute myelogenous leukemia, AML
Safety, Tolerability, Pharmacokinetics and Efficacy of AZD1208 in Acute Myelogenous Leukemia (AML) Patients Altman, Jessica K Leukemia, AML, AZD1208
The Role of Circadian Dysfunction in Hepatic Encephalopathy in Patients with Cirrhosis Kim, Minjee Cirrhosis, End-stage liver disease, hepatic encephalopathy, sleep, circadian, cognitive impairment, dementia, transplant, insomnia
Phase 2 Study Adding Pracinostat to a Hypomethylating Agent (HMA) in Patients With MDS Who Failed to Respond to Single Agent HMA Dinner, Shira Myelodysplastic Syndrome, MDS, pracinostat, Hypomethylating Agent, HMA, azacitadine, Vidaza, decitabine, dacogen
Daily Oral Regorafenib for Chemotherapy-Refractory, Metastatic and Locally Advanced Angiosarcoma Agulnik, Mark
A Phase Ib Study of MEK162 Plus BYL719 in Adult Patients With Selected Advanced Solid Tumors Chae, Young Kwang Advanced solid tumor,, AML, high risk and very high risk MDS, dose escalation,, RAS/BRAF mutation,, PI3K inhibitor,, MEK inhibitor,, BYL719,, MEK162
Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis Stein, Brady Lee
Volasertib in Combination With Low-dose Cytarabine in Patients Aged 65 Years and Above With Previously Untreated Acute Myeloid Leukaemia, Who Are Ineligible for Intensive Remission Induction Therapy (POLO-AML-2) Frankfurt, Olga
Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme Raizer, Jeffrey J BKM120,, Recurrent glioblastoma multiforme,, rGBM,, buparlisib
Study Comparing AEZS-108/ZoptEC (Zoptarelin Doxorubicin in Endometrial Cancer) to Doxorubicin as a Second Line Therapy of Endometrial Cancer Pineda, Mario
ANG1005 in Patients With Recurrent High-Grade Glioma Kumthekar, Priya glioma, glioblastoma, brain cancer, brain tumor, recurrent
A Study of TAK-659 in Adult Patients With Advanced Solid Tumor and Lymphoma Malignancies Kaplan, Jason TAK-659, Solid Tumors, CLL, DLBCL
The EVARREST™ Fibrin Sealant Patch Liver Study Baker, Talia Barzel Hepatobiliary Surgery
Safety Study of VM202 to Treat Amyotrophic Lateral Sclerosis Sufit, Robert L ALS, Lou Gehrig's disease, neurodegenerative disease
Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy Greenberger, Paul Allen
A Phase 2 Study of BGJ398 in Patients With Recurrent GBM Raizer, Jeffrey J BGJ398, recurrent glioblastoma', recurrent GBM, FGFR
A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Scar Revision Surgery in Healthy Adults Galiano, Robert D Hypertrophic scar, Cicatrix, Scar prevention, Scar revision
Efficacy and Safety Study of Intravenous to Oral Solithromycin (CEM-101) Compared to Intravenous to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia Wunderink, Richard G Pneumonia, CABP, CAP, Macrolide
Phase 1 Safety and Tolerability of MEDI4736 in Combination With Dabrafenib and Trametinib or With Trametinib Alone Chandra, Sunandana Metastatic or Unresectable Melanoma, MEDI4736, dafrafenib, trametinib, BRAF-mutation positive, wild-type BRAF, PD-L1, PD-1
Cardiovascular Improvements With MV ASV Therapy in Heart Failure Rich, Jonathan heart failure, congestive heart failure, acute decompensated heart failure, chronic heart failure, left-sided heart failure, heart failure decompensation, sleep apnea, sleep disordered breathing, central sleep apnea, obstructive sleep apnea, cheyne-stokes respiration
A Study of ARRY-520 and Carfilzomib in Patients With Advanced Multiple Myeloma Singhal, Seema
Phase IIb Safety and Efficacy Study of Four Dose Regimens of BAY1021189 in Patients With Heart Failure and Preserved Ejection Fraction Suffering From Worsening Chronic Heart Failure (SOCRATES-PRESERVED) Shah, Sanjiv J Worsening Heart Failure, Heart Failure with Preserved Ejection Fraction
An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Dinner, Shira Acute Myeloid Leukemia, AML, FMS-like tyrosine kinase 3, FLT3-ITD, Quizartinib, Leukemia, Tablets
Treatment for CI-DME in Eyes With Very Good VA Study Lyon, A Thayer Diabetic Macular Edema, anti-vascular endothelial growth factor
Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients With Moderate to Very Severe COPD Rosenberg, Sharon Reifler
The Study of an Investigational Drug, ALN-TTR02, for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis Ajroud-Driss, Senda RNAi therapeutic
Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss Weintraub, Sandra Cognition, Prevention, Dementia , Alzheimer's Disease, anti-amyloid antibody, Healthy adults
An Open-label, Multi-center, Expanded Treatment Protocol of Pasireotide LAR in Patients With Acromegaly Molitch, Mark E Acromegaly, Pituitary diseases
Safety and Immune Response of BMS-936559 in HIV-Infected People Taking Combination Antiretroviral Therapy Taiwo, Babafemi O
Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Meltzer, Herbert Alzheimer's disease, Cognition, Alpha-7 nAChR
Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure Courtney, D Mark Mark Chronic Heart Failure, CHF, Heart Failure, HF, Immunogenicity, Anti-bodies, Hypersensitivity, Serelaxin
Cytomegalovirus and BK Virus Nephropathy Biobank Cohort Study Ison, Michael G
A Pivotal Trial to Establish the Efficacy and Long-term Safety of the Parachute Implant System Davidson, Charles J Congestive Heart Failure Due to LV Systolic Dysfunction
A Prospective Study to Identify Risk Factors for Progressive Calcinosis in Patients with Systemic Sclerosis: A Scleroderma Clinical Trials Consortium Study Hinchcliff, Monique E scleroderma , calcinosis , calcinosis cutis , autoimmune , systemic sclerosis
Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study) Ruff Treiber, Ilana Phase III
BRAF Inhibitor, Vemurafenib, in Patients With Relapsed or Refractory Hairy Cell Leukemia Altman, Jessica K VEMURAFENIB (PLX4032 or R05185426), BRAF Inhibitor, 12-200
A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers Laumann, Anne E Lupus Erythematosus, Cutaneous, Lupus Erythematosus, Systemic, Lupus Erythematosus, Discoid, Healthy, Active Cutaneous Lupus Erythematosus, Longitudinal Study, Biomarkers, Subacute Cutaneous Lupus Erythematosus, Skin Biopsy
A Phase 2a Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis Schnitzer, Thomas J Pain, Osteoarthritis, Synovitis, Knee
A5320: Viral Hepatitis C Infection Long-term Cohort Study (V-HICS) Taiwo, Babafemi O hepatitis C, HIV, direct acting
A Phase 3 double-blind placebo-controlled parallel group study of isradipine as a disease modifying agent in subjects with early Parkinson disease Zadikoff, Cindy
Study of the Glutaminase Inhibitor CB-839 in Leukemia Frankfurt, Olga leukemia, glutaminase, glutamine
Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed/Refractory Marginal Zone Lymphoma Ma, Shuo MZL, NHL, SMZL, NMZL, MALT
A Study of the Efficacy and Safety of Activase (Alteplase) in Patients With Mild Stroke (PRISMS) Prabhakaran, Shyam
Safety and Efficacy of MK-5172 + MK-8742 in Participants With Chronic Hepatitis C and Chronic Kidney Disease (MK-5172-052) Ganger, Daniel R
Trichuris Suis Ova Treatment in Left-sided Ulcerative Colitis Hanauer, Stephen Ulcerative colitis, UC, Inflammatory Bowel Disease, IBD, TSO, T. suis, Trichuris suis ova
Conjugated Estrogens/Bazedoxifene in Treating Patients With Ductal Carcinoma in Situ Undergoing Surgery Kulkarni, Swati
A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carboplatin to Standard Chemotherapy Versus Standard Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer Gradishar, William J Oncology, Triple negative breast cancer, Austrian Breast & Colorectal Cancer Study Group - ABCSG 44, National Surgical Adjuvant Breast and Bowel Project - B-56-I, United States Oncology - 12152, Alliance - AFT-04, Grupo Español de Investigación del Cáncer de Mama - GEICAM/2014-02, German Breast Group - GBG 81
ANG1005 in HER2+ Breast Cancer Patients With Progressive/Recurrent Brain Metastases Kumthekar, Priya ANG1005, GRN1005, LRP-1, Targeted therapy, Breast cancer, Brain metastases, Brain tumor, Blood-brain barrier, Trastuzumab, Herceptin, Paclitaxel, Taxol, Breast cancer with brain metastases
A Study Evaluating ABT-199 in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy Singhal, Seema relapsed multiple myeloma, refractory multiple myeloma, relapsed/refractory multiple myeloma, multiple myeloma
Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) Shah, Sanjiv J
Parkinson’s Disease and Movement Disorders Center Biorepository Simuni, Tatyana
Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer Kulik, Laura M Immunosuppressive Agents, Liver Transplantation, HCC
A Study of CSL362 in Patients With CD123+ Acute Myeloid Leukemia Currently in Remission Altman, Jessica K
Dovitinib for Patients With Tumor Pathway Activations Inhibited by Dovitinib Chae, Young Kwang Solid tumor malignancy, hematologic malignancy, mutation, translocations, FGFR, PDGFR, VEGF, cKIT, FLT3, CSR1, Trk, RET, TKI258, dovitinib, signature, AML, acute myelogenous leukemia, GIST, gastrointestinal stromal tumor, Head and Neck cancer, Melanoma, NSCLC, non-small cell lung carcinoma, lung cancer, ovarian cancer, thyroid cancer, amplification
LGX818 for Patients With BRAFV600 Mutated Tumors Chae, Young Kwang
Selinexor (KPT-330) in Older Patients With Relapsed AML Frankfurt, Olga Relapsed/Refractory Acute Myeloid Leukemia, Acute Myeloid Leukemia, AML, Karyopharm, Selinexor, KPT-330
Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy Sutton, Sarah H Pregnancy, Pharmacokinetics, Treatment Experienced
Tracking the evolution of spasticity in acute stroke. Suresh, Nina
Double-Blinded, Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Biochemical Activity of Intravenous Cpn10 Administration in Subjects With SLE. Hsieh, Christine
Belatacept 3 Month Post Transplant Conversion Study Gallon, Lorenzo Kidney, Renal, Transplant, EBV, Immunosuppressants, Belatacept
Study of the Safety and Efficacy of REGN1033 (SAR391786) in Patients With Sarcopenia McDermott, Mary McGrae Douglas
TR-701 FA vs Linezolid for the Treatment of Nosocomial Pneumonia Wunderink, Richard G Pneumonia, Tedizolid Phosphate, TR-701
Thighplasty of transfemoral amputee residual limbs to improve prosthesis fit and patient functional outcomes Kuiken, Todd A
Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation Jain, Manu CF
Sofosbuvir Plus Ribavirin For Acute Hepatitis C in HIV-infected Individuals (SWIFT-C) Taiwo, Babafemi O
Time Restricted Diet in Obese or Overweight Pre or Postmenopausal Participants Khan, Seema Ahsan Ahsan
An e-Health Intervention to Improve Symptom Burden and Health-Related Quality of Life among Hispanic Women Completing Active Treatment for Breast Cancer Yanez, Betina Breast Cancer, Cancer de Seno, Cancer de Mama, Latina, Hispana, Español, Sobreviviente, Cancer Survivor
A Phase I, Single Center Trial of Adoptive Immunotherapy With T-reg Adoptive Cell Transfer (TRACT) to Prevent Rejection in Living Donor Kidney Transplant Recipients Skaro, Anton I Kidney transplant, Regulatory T cells, Leukopheresis, Immune cells, Stem Cells, Tolerance
Dose-ranging Study of Rifaximin Soluble Solid Dispersion (SSD) Tablets for the Prevention of Complications of Early Decompensated Liver Cirrhosis Moore, Christopher
Phase II Pazopanib Plus Topotecan for Recurrent Glioblastoma Multiforme (GBM) Raizer, Jeffrey J Brain Neoplasms, Central Nervous System Neoplasms, CNS, Recurrent glioblastoma, rGBM, Brain tumor, Intracranial glioblastoma multiforme, GBM, Gliosarcoma, GS, Pazopanib, GW786034, Topotecan, Hycamtin, Symptom questionnaire, Phone calls
HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network Levitsky, Josh Hepatitis, Hepatitis C, HCV-TARGET, HCV, Observational Study
Efficacy and Safety Study of AeroVanc for the Treatment of Persistent MRSA Lung Infection in Cystic Fibrosis Patients Jain, Manu Cystic Fibrosis, MRSA, Methicillin-resistant Staphylococcus aureus, Lung infection, AeroVanc, Vancomycin
Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery Nimeiri, Halla S
B-WELL-Mom (Breathe-Wellbeing, Environment, Lifestyle, and Lung Function) Grobman, William A Asthma, Pregnancy, Lung function, immune response
Phase 3 Study to Treat Patients With Soft Tissue Sarcomas Agulnik, Mark soft tissue sarcoma, unresectable, metastatic, locally advanced, sarcoma
The Scleroderma Patient-Centered Intervention Network (SPIN) Cohort Varga, John scleroderma , skin disease , quality of life , skin fibrosis , autoimmune , systemic sclerosis , patient reported outcomes, PROs, support
Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Ma, Shuo
Ex vivo interactions between high-density-like nanoparticles and human blood Thaxton, Colby S cholesterol, HDL, LDL
Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During Open Surgeries Baker, Talia Barzel Hemostasis, Vascular open surgery, Hepatic open surgery, Soft tissue open surgery, Spinal open surgery, during vascular, parenchymous tissue (hepatic), soft tissue, and spinal open surgical procedures.
Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer Berry, Emily
Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction Shah, Sanjiv J Heart Failure, Preserved Ejection Fraction
Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia Ma, Shuo
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD) Including GSPECT (Gated Single Photon Emission Computed Tomography) Carr, James Myocardial Perfusion Imaging
A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT) Mehta, Jayesh ASP0113, Cytomegalovirus (CMV), Hematopoietic Cell Transplant (HCT)
Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer Mulcahy, Mary Frances Pancreatic Cancer, Immunotherapy, Vaccine Therapy
Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme Kumthekar, Priya Glioma Associated Antigen, Vaccine, Adult, Recurrent Glioblastoma, Immunotherapy
Olaparib Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy. Shahabi, Shohreh BRCA, Ovarian Cancer, Chemotherapy, PARP inhibitor, First Line, FIGO Stage III, FIGO Stage IV
Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at High Risk of Acquiring HIV-1 Infection Yogev, Ram
EDIC Hearing Ancillary Study Molitch, Mark E
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC) Hanauer, Stephen Registry, Gastrointestinal Diseases, Inflammatory Bowel Diseases, Gastroenteritis, Adalimumab, Colitis, Ulcerative Colitis
Development of an eHealth-based Cognitive Behavioral Stress and Self-Management Intervention to Reduce Symptom Burden in HIV+ Gay and Bisexual Men and Trans Women Treated for Non-Metastatic Cancer Penedo, Frank J cancer , HIV, LGBT, gay, bisexual, trans, non-metastatic, localized
Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed By Surgery Chandra, Sunandana
ALLIANCE A021501 PREOPERATIVE EXTENDED CHEMOTHERAPY VS. CHEMOTHERAPY PLUS HYPOFRACTIONATED RADIATION THERAPY FOR BORDERLINE RESECTABLE ADENOCARCINOMA OF THE HEAD OF THE PANCREAS Kalyan, Aparna
Correlative Biomarker Study in Patients With Myeloproliferative Disorders Adekola, Kehinde Myeloproliferative Disease, Myelofibrosis, Idiopathic Myelofibrosis, Essential Thrombocythemia, Polycythemia Vera, Biomarkers, Philadelphia Chromosome Negative, Clonal Hematopoietic malignancies
Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled Asthma Avila, Pedro C Asthma,, Bronchial Diseases,, Respiratory Tract Diseases,, Lung Diseases,, Obstructive Lung Diseases
Efficacy and Safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Single-Tablet Regimen in HIV-1/Hepatitis B Co-infected Adults Hawkins, Claudia A HIV, HBV, Coinfection
A Blanket Protocol to Study Oral Regorafenib in Patients With Refractory Liposarcoma, Osteogenic Sarcoma, and Ewing/Ewing-like Sarcomas Agulnik, Mark
Study of Efficacy and Safety of Brodalumab in Subjects With Psoriatic Arthritis Ruderman, Eric M Psoriatic Arthritis, Brodalumab, AMG 827
Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial Prabhakaran, Shyam stroke, diabetes, hyperglycemia
THE RELATIONSHIP OF PAI-1 ISOFORMS WITH CORONARY THROMBOSIS, CARDIAC FIBROSIS, AND CLINICAL EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROMES Vaughan, Douglas E
Phase 2 Study of NGM282 in Patients With Primary Biliary Cirrhosis Rinella, Mary Eugenia
Can active elbow extension reduce shoulder loading in C5/C6 quadriplegia? Murray, Wendy M M.
Safety & Efficacy Study of TPI 287 + Avastin in Adults With Glioblastoma That Progressed Following Prior Avastin Therapy Kumthekar, Priya Glioblastoma multiforme, Glioblastoma, Radiotherapy, Temozolomide, TPI 287, Taxoid, Avastin, Bevacizumab
Evaluation of CureXcell® in Treating Chronic Venous Leg Ulcers Galiano, Robert D Chronic ulcers, Venous ulcers
Prospective Analysis of Micro-RNA profiling as a Biomarker for Prostate Cancer Meeks, Joshua J active surveillance, prostate cancer, PSA
Steroids In Eosinophil Negative Asthma Smith, Lewis J steroids, shortness of breath, wheezing, coughing, chest tightness, lungs, eosinophils
Use of Radiofrequency Ablation for RGB Salvage Komanduri, Srinadh RGB Salvage, RFA
The Chimerix CMX001 Registry Ison, Michael G
Study to Evaluate SAGE-547 Injection as Therapy in the Treatment of Adults With Super-Refractory Status Epilepticus Gerard, Elizabeth Erway Status Epilepticus, Refractory status epilepticus, Super-refractory status epilepticus, SAGE-547, SAGE, Sage Therapeutics
Santyl Applications to Diabetic Foot Ulcers Galiano, Robert D Diabetic Foot Ulcers, Diabetic Foot Wounds
Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye Chandra, Sunandana
Study to Evaluate the Safety and Efficacy of Two Drug Regimens in Subjects With Moderate to Severe Ulcerative Colitis Hanauer, Stephen Ulcerative Colitis
A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix Grobman, William A women, cervical length of less than 30 millimeters, carrying twins
Safety, Tolerability, Pharmacokinetics, and Preliminary Pharmacodynamics of QBW251 in Healthy Subjects and Cystic Fibrosis Patients Jain, Manu FEV1- Forced Expiratory volume, LCI - Lung Clearance Index, CFTR - cystic fibrosis transmembrane conductance regulator
Healthy Control Esophageal Registry and Biorepository Hirano, Ikuo healthy control , scleroderma , GERD, scleroderma esophagus
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF SD-809 (DEUTETRABENAZINE) FOR THE TREATMENT OF MODERATE TO SEVERE TARDIVE DYSKINESIA Simuni, Tatyana
Ibrutinib With Rituximab in Previously Treated Adults With Waldenstrom's Macroglobulinemia Ma, Shuo Ibrutinib, Pharmacyclics, PCYC, Lymphoma, Btk inhibitor, WM, Rituximab, Rituxan, Waldenstrom's, Waldenstrom Macroglobulinemia, non-Hodgkin lymphoma, NHL
Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis Gordon, Kenneth Atopic Dermatitis, Atopic Eczema
New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C Flamm, Steven L Hepatitis C, Non-Responders, Direct Acting Antivirals, Interferon Free, Cirrhosis
Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme Kumthekar, Priya
Comparative Effectiveness of a Genomics Assay for Active Surveillance Failure Prediction in African American Men Murphy, Adam
A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Altman, Jessica K ASP2215, Cytarabine, Idarubicin, Acute Myeloid Leukemia
Neural representation of olfactory rewards in the human brain Kahnt, Thorsten
ASSOCIATION OF PAI-1 AND FGF23 IN PATIENTS WITH KIDNEY DISEASE Vaughan, Douglas E
BKM120 for Patients With PI3K-activated Tumors Chae, Young Kwang Solid tumor, malignancy, hematologi malignancy, PI3K pathway activation, BKM120, signature, AML, acute myelogenous leukemia, cervical, ovarian, hepatobiliary, buparlisib
AdaptResponse Clinical Trial Lin, Albert AdaptivCRT, aCRT, center for heart rhythm disorders, LBBB
Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia Stein, Brady Lee Polycythemia, Polycythemia Vera, Essential Thrombocythemia, Thrombocytosis, Myeloproliferative Disorders, Bone Marrow Diseases, Hematologic Diseases, Blood Coagulation Disorders, Blood Platelet Disorders, Hemorrhagic Disorders
Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF Stein, Brady Lee
Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer Gradishar, William J Genomically-Directed Therapy, DNA Sequencing
Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral Therapy Taiwo, Babafemi O
Oral Pacritinib Versus Best Available Therapy to Treat Myelofibrosis With Thrombocytopenia Stein, Brady Lee Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis, Primary Myelofibrosis, Polycythemia, Polycythemia Vera, Thrombocythemia, Essential, Thrombocythemia, Myeloproliferative Disorders, Bone Marrow Disease, Hematologic Diseases, Blood Platelet Disorders, Hemorrhagic Disorders, Splenomegaly, Pacritinib, MPN-SAF, MPN-SAF TSS, Anemia, Myeloproliferative, Myeloproliferative Neoplasm, Spleen, Spleen volume, Thrombocytopenia, SB1518
Staging Intracranial Hemodynamic Failure with MRI Ansari, Sameer Ahmad
Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis Hirano, Ikuo
Safety and Efficacy Study of Sebelipase Alfa in Patients With Lysosomal Acid Lipase Deficiency Nemcek Jr, Albert A Enzyme Replacement Therapy (ERT), Lysosomal Storage Disease, Late Onset Lysosomal Acid Lipase (LAL) Deficiency, Acid cholesteryl ester hydrolase deficiency, type 2, Acid lipase disease, Cholesterol ester hydrolase deficiency, LAL Deficiency, LIPA Deficiency, Wolman disease, Additional relevant MeSH terms:, Cholesterol Ester Storage Disease, Wolman Disease, Metabolic Diseases, Lipidoses, Lipid Metabolism, Inborn Errors, Metabolism, Inborn Errors, Genetic Diseases, Inborn, Lysosomal Storage Diseases, Lipid Metabolism Disorders, Infant, Newborn, Diseases
Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed By the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed By Surgery Hayes, John P
LDE225 for Patients With PTCH1 or SMO Mutated Tumors Chae, Young Kwang Solid tumor malignancy,, hematologic malignancy,, mutation, translocations,, signature,, PTCH1,, SMO,, LDE225,, endometrial cancer,, colon cancer,, bladder,, NSCLC
LCH_Measuring Human BAT Volume and Activity by Quantitative and Functional MRI (2014-15761) Deng, Jie
Efficacy, Safety, Tolerability of Carbavance Compared to Best Available Therapy in Serious Infections Due to Carbapenem Resistant Enterobacteriaceae, in Adults Wunderink, Richard G
LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009) Kalhan, Ravi
Comparison of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 24 Weeks in Adults With Chronic Genotype 3 HCV Infection Flamm, Steven L Sofosbuvir, SOF/GS-5816, GS-5816, Hepatitis C, HCV, cirrhosis
Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity Spring, Bonnie obesity, weight, weight loss, diet , physical activity, health
A Phase 2 Open-Label Study of the Efficacy and Safety of ABT-199 (GDC-0199) in Chronic Lymphocytic Leukemia (CLL) Subjects With Relapse or Refractory to B-Cell Receptor Signaling Pathway Inhibitor Therapy Ma, Shuo Chronic Lymphocytic Leukemia, Oncology, Cancer of the blood and bone marrow
(CIRB) A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Effect of Long-term Treatment with BELVIQ (lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects with Cardiovascular Disease or Multiple Cardiovascular Risk Factors Kushner, Robert F
Glycemic Control and Treatment Satisfaction Using Finesse Versus Pen for Initiating Bolus Insulin Dosing in Type 2 Diabetes Mellitus Patients Not Achieving Glycemic Targets on Basal Insulin With/Without Anti-Hyperglycemic Agents Molitch, Mark E
Comparison of Level of Consciousness in Women Undergoing Scheduled versus Unscheduled Cesarean Deliveries Bauchat, Jeanette
Study of Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (SADAL) Kaplan, Jason Diffuse large B-cell Lymphoma, DLBCL, Karyopharm, KPT-330, selinexor
Open Label Study to Evaluate Long Term Efficacy, Safety and Tolerability of Repeated Dosing in Subjects With Crohn's Disease and Who Participated and Successfully Completed M14-115 Hanauer, Stephen Crohn's Disease
Neural Systems for the Dynamic Use of Memory Voss, Joel
Necessary roles of PFC-MTL interactions in memory tested in humans using TMS Voss, Joel
Deep Brain Stimulation (DBS) for the Treatment of Parkinson's Disease Rosenow, Joshua M Intrepid, Vercise, PD, DBS, Boston Scientific, Parkinson's Disease
Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy Khan, Seema Ahsan Ahsan
PREVENtion of HeartMate II Pump Thrombosis Rich, Jonathan HeartMate II, heart assist device, pump thrombosis, hypercoagulable disorder, thrombus
A Phase 2 Study of MPDL3280A (an Engineered Anti-PDL1 Antibody) as Monotherapy or in Combination With Avastin (Bevacizumab) Compared to Sunitinib in Patients With Untreated Advanced Renal Cell Carcinoma Kuzel, Timothy Michael
Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease Molitch, Mark E LCI699, Cushing's disease
Validation and Testing of a Smartphone Application to Measure Sleep Baron, Kelly Glazer
Multi-site study of the efficacy of speech perception training for hearing aid users Souza, Pamela Elizabeth
Liver Function Measured by HepQuant-SHUNT in the Prediction of Outcomes in Patients with Passive Hepatic Congestion Secondary to Congenital Heart Disease (CHD) or Cardiomyopathy Ganger, Daniel R congenital heart disease, cardiomyopathy, liver disease
Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia Wunderink, Richard G Ventilator-associated bacterial pneumonia, Hospital-acquired bacterial pneumonia, Pneumonia, Lung Diseases, Respiratory Tract Diseases, Respiratory Tract Infections, Infection, Ventilator-Induced Lung Injury, Lung Injury
A Study to Assess the Safety and Efficacy of the VEGFR-FGFR Inhibitor, Lucitanib, Given to Patients With FGF Aberrant Metastatic Breast Cancer Gradishar, William J Breast cancer, Metastatic breast cancer, MBC, HER2 positive, HER2+, Estrogen receptor positive, ER+, Triple negative, FGFR1, 11q, FGF aberrant
Sofosbuvir/GS-5816 Fixed-Dose Combination in Adults With Chronic HCV Infection and Child-Pugh Class B Cirrhosis Flamm, Steven L
Improving Outpatient Safety of Older Adults through Electronic Patient Portals Lindquist, Lee A caregiver, geriatrics, MyChart, senior , electronic patient portal
Freehand Ultrasound to Evaluate Scapular Kinematics in People With Paraplegia Dhaher, Yasin Y Ultrasound, Shoulder, Spinal Cord Injury, Fluoroscopy
Application of Targeted Reinnervation for People With Transradial Amputation Kuiken, Todd A Transradial amputee
Molecular Effects of Topical Calcipotriene on Morphea Graham, Lauren
Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection Flamm, Steven L Sofosbuvir, SOF/GS-5816, GS-5816, Hepatitis C, HCV, cirrhosis
Evaluate the Effect of Elimune Capsules Gordon, Kenneth Plaque, Psoriasis, Biomarkers, CRP, αTNF, Interleuken
A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD) Kalhan, Ravi umeclidinium, COPD, fluticasone furoate, triple therapy, vilanterol, exacerbation
BOTOX® Efficacy and Safety in the Treatment of Knee Osteoarthritis Schnitzer, Thomas J
Efficacy and Safety Study of Benralizumab to Reduce OCS Use in Patients With Uncontrolled Asthma on High Dose Inhaled Corticosteroid Plus LABA and Chronic OCS Therapy Avila, Pedro C Asthma, Bronchial Diseases, Respiratory Tract Diseases, Lung Diseases, Obstructive Lung Diseases, OCS, Oral Corticosteroids
Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214) Kuzel, Timothy Michael
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers Hitsman, Brian L Smoking Cessation, Major Depressive Disorder, Nicotine Dependence, Varenicline, Behavioral Activation Therapy, Cigarette Smoking
Study of Dupilumab (REGN668/ SAR231893) and Immune Responses in Adults With Atopic Dermatitis (AD) Gordon, Kenneth
Efficacy, Pharmacokinetics, and Safety of GS-5806 in Hospitalized Adults With Respiratory Syncytial Virus (RSV) Infection Ison, Michael G
Association Between Bolus Rate and Duration of Adequate Labor Analgesia Lange, Elizabeth epidural bolus, pain management, labor analgesia
A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection Flamm, Steven L Treatment-Experienced, Naïve, Non responder, Cirrhosis, Null responder, Hepatitis C Virus, Relapser, Compensated Cirrhosis, Hepatitis C Genotype 1, Hepatitis C
Open Label Safety and Efficacy Study of CO-1686 in Patients With T790M Positive NSCLC Who Have Failed One Previous EGFR-Directed TKI Mohindra, Nisha cancer, metastatic, locally advanced, lung, non-small cell lung cancer, NSCLC, epidermal growth factor receptor, EGFR, T790M, CO-1686, unresectable, recurrent, EGFR-directed therapy, irreversible EGFR inhibitor
A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies Chae, Young Kwang Non-Small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Diffuse Large B-cell Lymphoma, programmed death 1, programmed dealth ligand 1, cytotoxic T-lymphocyte-associated antigen-4, OX40 ligand
Evaluation of the IBV® Valve for Emphysema to Improve Lung Function Kalhan, Ravi Bronchoscopic Lung Volume Reduction, Emphysema, Lung Diseases, coil, chronic bronchitis, shortness of breath, coughing
Ticagrelor in Severe Community Acquired Pneumonia Wunderink, Richard G CAP, Pneumonia, Intensive Care Unit, Mechanical Ventilation
Radiographic Markers of Clinical Function in Cervical Spondylotic Myelopathy (CSM) Smith, Zachary MRI, spine, x-ray, control
Treatment of Pain Associated With Fibromyalgia Schnitzer, Thomas J pain, fibromyalgia
A Study of the Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis Patients Who Are Naive to TNF Inhibitors Hanauer, Stephen
A Phase 2 Trial of Filanesib in Relapsed/Refractory Multiple Myeloma (AfFIRM) Singhal, Seema
Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE) Chae, Young Kwang hematological malignancy, solid tumor malignancy, mutation, translocation, rearrangement, amplification, ALK, ROS1, NSCLC, B-cell lymphoma
Lung-MAP: S1400 Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IIIB-IV Squamous Cell Lung Cancer Chae, Young Kwang
Comparison of Sofosbuvir/GS-5816 Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 12 Weeks in Adults With Chronic Genotype 2 HCV Infection Flamm, Steven L Hepatitis C, HCV, cirrhosis, Sofosbuvir, Sovaldi, SOF/GS-5816, GS-5816, GS-7977, liver, Treatment naive, Treatment Experience
Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Goldstein, Debra uveitis, macular edema, UME, posterior uveitis, anterior uveitis, panuveitis, intermediate uveitis, noninfectious uveitis, triamcinolone acetonide, suprachoroidal space, injection, microneedle, intravitreal injection, corticosteroid, CME, choroid, retina, microinjection, SCS
Bay98-7196, Dose Finding / POC Study Robins, Jared
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-Administration of ABT-493 and ABT-530 With and Without RBV in Subjects With Chronic Hepatitis C Virus (HCV) Genotype 2 or Genotype 3 Infection Flamm, Steven L Chronic Hepatitis C, Hepatitis C Virus, Hepatitis C Genotype 3, Hepatitis C, Hepatitis C Genotype 2, interferon free, HCV
A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars Galiano, Robert D Hypertrophic scar, Cicatrix, Scar prevention, Scar revision
Effect of a Patient-Centered Decision App on TOLAC Grobman, William A Trial of labor after cesarean, Elective repeat cesarean delivery, Decision tool, Shared decision making
Efficacy and Safety of Subcutaneous Secukinumab in Adults With Moderate to Severe Scalp Psoriasis. Gordon, Kenneth scalp psoriasis, plaque psoriasis, secukinumab, AIN457, biologic, monoclonal antibody, psoriasis, AIN457A
Assessment of Patient Positioning Ladner, Daniela P nerve compression
Rheumatoid Arthritis Synovial tissue Network Pope, Richard M Synovitis, swollen joints, rheumatoid arthritis
Rehabilitation Institute of Chicago Recruitment Registry Lieber, Richard
Dolutegravir Antiretroviral Strategy to Promote Improvement and Reduce Drug Exposure Taiwo, Babafemi O
A Phase 2a Study Evaluating the Safety and Efficacy of ABT-981 in Patients With Erosive Hand Osteoarthritis Schnitzer, Thomas J Osteoarthritis, Hand, Osteoarthritis, Musculoskeletal diseases, Joint diseases, Arthritis, Rheumatic diseases
Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can be Removed by Surgery Agulnik, Mark
Study of the Safety and Activity of Lenvatinib (E7080) in Subjects With KIF5B-RET-Positive Adenocarcinoma of the Lung Chae, Young Kwang KIF5B-RET-Positive Adenocarcinoma, Lung Cancer, NSCLC, Non-Small Cell Lung Cancer
Alendronate to Prevent Loss of Bronchoprotection in Asthma Smith, Lewis J
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery Mohindra, Nisha
Safety and Efficacy Study of Rociletinib (CO-1686) or Erlotinib in Patients With EGFR Mutant NSCLC Who Have Not Had Any Previous EGFR Directed Therapy Mohindra, Nisha cancer, metastatic, locally advanced, lung, non-small cell lung cancer, NSCLC, epidermal growth factor receptor, EGFR, T790M, CO-1686, unresectable, recurrent, EGFR-directed therapy, irreversible EGFR inhibitor, TIGER, rociletinib
LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE) Chae, Young Kwang Solid malignancy, Hematologic malignancy, Mutations, Amplifications, Signature, CDK4, CDK6, CDK4/6, Cyclin D1, CCND1, Cyclin D3, CCND3, p16 mutation, CDKN2A, LEE011, Breast cancer, Ovarian cancer, Lymphoma, Mesothelioma, Pancreatic neuroendocrine, Leukemia, Tumor
Black Patients' Lived Experiences and Perceptions of Skin of Color Clinics Patterson, Stavonnie
Efficacy and Safety Study of Gevokizumab to Treat Behcet's Disease Uveitis Goldstein, Debra Uveitis, Behcet's Disease Uveitis, Behcet's Disease
DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis Shah, Sanjiv J Cardiomyopathy, Heart Failure, FAC, Amyloid, Transthyretin (TTR)
A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behcet's Disease Brown Jr, Calvin R APREMILAST (CC-10004), CC-10004, Efficacy, Safety, Phase 3, Behçet's Disease
Radiation Therapy With Cisplatin, Docetaxel, or Cetuximab After Surgery in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Mittal, Bharat B
Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas Agulnik, Mark
Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Kruser, Timothy
Tolvaptan Phase 3 Efficacy and Safety Study in ADPKD Tuazon, Jennifer A ADPKD, Polycystic, kidney, ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Carboplatin/Nab-Paclitaxel and MK-3475 in NSCLC Mohindra, Nisha MK-3475, Pembrolizumab, Carboplatin, Nab-paclitaxel
Efficacy and Safety Study as Monotherapy of SA237 to Treat NMO and NMOSD Cohen, Bruce Arnold
Efficacy and Safety Study of WTX101 in Adult Wilson Disease Patients Bega, Danny
A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC Chae, Young Kwang NSCLC, Non-Small Cell Lung Cancer, heregulin, ErbB3, docetaxel, pemetrexed
Low InTensity Exercise Intervention in PAD McDermott, Mary McGrae Douglas peripheral arterial disease, peripheral artery disease, PAD, exercise
Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme Kumthekar, Priya
Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides) Guitart, Joan CTCL, Mycosis fungoides, Hypericin, SGX301, MF
Observational US Study Assessing Outcomes, Treatment Patterns, AEs, QOL in MF-CTCL Patients and Treated With Valchlor Guitart, Joan Mycosis Fungoides, Cutaneous T-cell lymphoma, CTCL
GS-5806 in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus Infection of the Upper Respiratory Tract Ison, Michael G Respiratory Syncytial Virus (RSV), Antiviral, Hematopoietic Cell Transplant (HCT), Upper respiratory tract infection
Non-Invasive Evaluation of Liver Hemodynamics in Live Donor Liver Transplantation Collins, Jeremy
Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) Weintraub, Sandra FTLD, Frontotemporal Dementia, Frontotemporal Lobar Degeneration, Primary Progressive Aphasia, progressive supranuclear palsy syndrome, Corticobasal Degeneration Syndrome, Registry
Selinexor Treatment of Advanced Relapsed/Refractory Squamous Cell Carcinomas Nimeiri, Halla S Squamous, SCC, Carcinoma, KPT-330, SINE, Selinexor, Karyopharm, Karyopharm Therapeutics, Lung, Head, Neck, Esophageal
GS-5806 in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus (RSV) Infection of the Lower Respiratory Tract Ison, Michael G Respiratory Syncytial Virus (RSV), Antiviral, Hematopoietic Cell Transplant (HCT), Lower respiratory tract infection
Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease Jain, Manu
Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation Jain, Manu
A Phase IIa Multi-Center Study of 18F-FDG PET, Safety, and Tolerability of AZD0530 in Mild Alzheimer's Disease Bonakdarpour, Borna
Lithium Therapy: Understanding Mothers, Mood and Metabolism Clark, Crystal
RESOLVE II Clinical Evaluation of Safety and Efficacy of S8 Sinus Implant in Chronic Sinusitis Patients Tan, Bruce Kuang-Huay K
Comparative treatment analysis of patients with combined-type femoroacetabular impingement undergoing hip arthroscopy with either isolated acetabular osteoplasty or combined femoral and acetabular osteoplasty: A prospective study Stover, Michael
Assessment of Femoral or Acetabular Chondral Defects in the Hip following Microfracture: Utilization of MR Imaging Omar, Imran M
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial Eskandari, Mark asymptomatic, carotid, stent, endarterectomy, embolic protection, medical management, hypertension, hyperlipidemia, cognition, risk factor control
To Evaluate the Impact of SBI on C. Difficile in Hospitalized UC Patients Hanauer, Stephen CDI, C. diff, Ulcerative Colitis, UC, IBD, Inflammatory Bowel Disease
Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis Gordon, Kenneth Phase 2, randomized, double-blind, placebo, plaque, psoriasis, safety, efficacy, JAK, janus kinase, moderate, severe
The Effect of Magnesium on Maternal Mood, Cognitive Function, and Birth Experience Miller, Emily
Beraprost-314d Added-on to Tyvaso® (BEAT) Cuttica, Michael J
Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET) Stein, Brady Lee Polycythemia vera, Essential thrombocythemia, Hydroxyurea, PEGASYS, Pegylated Interferon Alfa-2a
Methylation Patterns of Committed, Stable Th17 Cells Predicts Asthma Severity: A Pilot Study Smith, Lewis J
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting Levitsky, Josh liver transplant, hepatitis C, Gilead, Communicable Diseases, Infection, Virus Diseases, Digestive System Diseases, Hepatitis, Viral, Human, Liver Diseases, RNA Virus Infections
Investigation of how nulliparous women make decisions regarding epidural use for labor analgesia Toledo, Paloma
Odontoid Fracture Study Treated With Pulsed Electromagnetic Fields Hsu, Wellington K PEMF, odontoid fracture, IDE, prospective
Randomized, double-blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate (110 mg or 150 mg, oral b.i.d.) versus acetylsalicylic acid (100 mg oral q.d.) in patients with Embolic Stroke of Undetermined Source (RESPECT ESUS) Caprio, Fan
Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer Mittal, Bharat B
SANTE - Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy Ajroud-Driss, Senda Direct brain stimulation, SANTE
Phase 3 Study With Dual Release Ciprofloxacin for Inhalation in Non-CF Bronchiectasis Prickett, Michelle Lee Non Cystic Fibrosis Bronchiectasis, Pulmaquin, Ciprofloxacin, Pseudomonas aeruginosa
Pegylated Interferon Alfa-2a Salvage Therapy in High Risk Polycythemia Vera (PV) or Essential Thrombocythemia (ET) Stein, Brady Lee Polycythemia Vera, Essential Thrombocythemia, Hydroxyurea Resistant, Abdominal Vein Thrombosis, PEGASYS
An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum Laumann, Anne E Pyoderma Gangrenosum, Classic Pyoderma Gangrenosum
A 2-Year, Open-Label, Safety Extension Study of Gevokizumab in Subjects With Pyoderma Gangrenosum Laumann, Anne E Pyoderma Gangrenosum, Classic Pyoderma Gangrenosum
A5324: A Randomized, Double-Blinded, Placebo-Controlled Trial Comparing Antiretroviral Intensification with Maraviroc and Dolutegravir with No Intensification or Intensification with Dolutegravir Alone for the Treatment of Cognitive Impairment in HIV Taiwo, Babafemi O HIV infection, neurocognitive impairment, antiretroviral treatment, neuropsychologic testing
SPARC: Gene expression profiling in scleroderma to discover therapeutic targets and predict clinical course Varga, John scleroderma , inflammatory , fibrosis, systemic sclerosis , autoimmune , skin fibrosis , healthy control
Study of Dupilumab in Adult Patients With Active Eosinophilic Esophagitis (EoE) Hirano, Ikuo
OPsumit USers Registry Cuttica, Michael J pulmonary arterial hypertension, PAH
MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients Flaum, Lisa HER2-positive, HER2+, HER2, Locally Advanced Breast Cancer, Metastatic Breast Cancer, trastuzumab, Herceptin, pertuzumab, ado-trastuzumab emtansine, TDM-1, Perjeta, Kadcyla
Study of Human Central Nervous System (CNS) Stem Cell Transplantation in Cervical Spinal Cord Injury Ganju, Aruna spine, injury, trauma, spine injury, cervical spine injury, cervical spine, stemcells transplantation
MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ Khan, Seema Ahsan Ahsan
ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancer Benson III, Al B
[Trial of device that is not approved or cleared by the U.S. FDA] Rinella, Mary Eugenia
Motor impairment related changes in muscles properties in chronic stroke Dewald, Julius P P
HIV acquisition among African-born US residents Taiwo, Babafemi O HIV, HIV diagnosis, African born
Pembrolizumab Alone and In Combination With ACP-196 in Subjects With Advanced Non-small Cell Lung Cancer Mohindra, Nisha
Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia Grobman, William A Preeclampsia, Preterm preeclampsia, Pregnancy
Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study Weintraub, Sandra amyloid imaging, biomarkers, cognition, longitudinal, cognitive decline, observational
NUYou:mHealth Intervention to Preserve and Promote Ideal Cardiovascular Health Spring, Bonnie Mobile Health, Smartphone, Cardiovascular health, College students, Smoking, Physical activity, Diet, BMI, Blood pressure, Cholesterol, Glucose, Text, Facebook, Instagram, Push Notifications, Ecological Momentary Assessment
PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial Cuttica, Michael J
Biochronicity Grand Challenge: Human Time Stamp Development, Validation and Prediction Zee, Phyllis C traumatic brain injury
Etanercept and Methotrexate in Combination or as Monotherapy in Psoriatic Arthritis Ruderman, Eric M Psoriatic Arthritis, Arthritis, Psoriasis, Etanercept, Enbrel, Methotrexate, Minimal Disease Activity
Evaluation of t-RFA and RF-TVA Prior to/Following Radiation Therapy to Treat Painful Metastatic Vertebral Body Tumor(s) Ansari, Sameer Ahmad metastatic lesions, vertebral body, ablation, radiation, targeted radio-frequency ablation, radio-frequency targeted vertebral augmentation, radiofrequency kyphoplasty, spine, vertebral augmentation, kyphoplasty, spinal ablation, pain, quality of life, spinal tumors
Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis Agulnik, Mark
Nivolumab in Treating Patients With Refractory Metastatic Squamous Cell Carcinoma of the Anal Canal Kircher, Sheetal
Treating verbal memory deficits following chemotherapy for breast cancer Cherney, Leora R breast cancer, verbal memory, mental processing speed, computerized therapy
Targeted Reinnervation as a Means to Treat Neuromas Associated With Major Limb Amputation Alghoul, Mohammed Assessment, Pain
Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002 Schnitzer, Thomas J Osteoarthritis, Pain, Fulranumab, JNJ-42160443, Monotherapy, Hip, Knee, Joint replacement surgery
Phase 3 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cirrhosis Flamm, Steven L Primary Biliary Cirrhosis, PBC, Cirrhosis, Liver
Association of Donor Age With Recipient Outcomes in Kidney Transplant Gallon, Lorenzo kidney, transplant
Trans-MAPP Symptom Patterns Study (SPS) Schaeffer, Anthony J pelvic pain, bladder pain
CLINICAL STUDY TO EVALUATE THE EFFECTIVENESS OF CUTIMED SILTEC B AND CUTIMED SORBACTDRESSINGS WITH JOBST ULCER CARE COMPRESSION FOR THE MANAGEMENT OF VENOUS LEG ULCERS Galiano, Robert D
Study of REGN475 in Patients With Pain Due to Osteoarthritis of the Knee or Hip Schnitzer, Thomas J
Study of Efficacy, Safety of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3001 Schnitzer, Thomas J Osteoarthritis, Pain, Fulranumab, JNJ-42160443, Adjunctive therapy, Opioid, Hip, Knee, Joint replacement surgery
Population health management for smoking cessation in low income smokers: A preliminary comparison with usual care and extension to smoking cessation Hitsman, Brian L
SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE) Simuni, Tatyana PDD, Parkinson's Disease Dementia, patients taking a cholinesterase inhibitor.
Anxiety and COPD Evaluation Smith, Lewis J
Phase Ib and Phase II Studies of MK-3475 in Combination + for Renal Cell Carcinoma: Kuzel, Timothy Michael MK-3475, Pembrolizumab, Bevacizumab
Cabozantinib-S-Malate in Treating Patients With Recurrent or Progressive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Shahabi, Shohreh
Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer Shahabi, Shohreh
The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence Kenton, Kimberly mixed urinary incontinence, stress incontinence, urgency incontinence, urinary leakage, midurethral sling
PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial Goldstein, Debra
Open-Label Safety Study of ADS-5102 in PD Patients With LID Bega, Danny Levodopa Induced Dyskinesia, LID, Parkinsonism, Parkinson's Disease
Efficacy and Safety Study of ADS-5102 in PD Patients With Levodopa-Induced Dyskinesia Bega, Danny Levodopa-Induced Dyskinesia, LID, Parkinsonism, Parkinson's Disease
Preferences for Activating and Adhering to Physical Activity with Arthritis (PAAPAyA): Choice experiment Pinto, Daniel
Sorafenib for Hepatopulmonary Syndrome Levitsky, Josh Randomized Controlled Trial, Clinical Trial, sorafenib, Hepatopulmonary Syndrome
Determinants of Coronary Microvascular Ischemia Shah, Sanjiv J
A Study of Pembrolizumab (MK-3475) Versus Paclitaxel for Participants With Advanced Gastric/Gastroesophageal Junction Adenocarcinoma That Progressed After Therapy With Platinum and Fluoropyrimidine (MK-3475-061/KEYNOTE-061) Benson III, Al B Gastric cancer, Gastroesophageal junction cancer
Telmisartan Plus Exercise to Improve Functioning in PAD McDermott, Mary McGrae Douglas peripheral artery disease, atherosclerosis, vascular disease, cardiovascular disease, telmisartan, exercise
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-493 and ABT-530 With and Without Ribavirin in Adults With Genotype 1 HCV Who Failed a Prior DAA Containing Therapy Flamm, Steven L HCV Genotype 1, Chronic Hepatitis C, HCV GT1, Interferon (IFN) free, Hepatitis C Genotype 1, Chronic HCV, Hepatitis C, HCV
Phase 1 Combination Study of MM-151 and MM-121 Chae, Young Kwang Heregulin-positive, EGFR, ErbB3, Phase I, Oncology, Cancer
A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors. Benson III, Al B Angiogenesis Inhibitor, Monoclonal Antibody, Vascular Endothelial Growth Factor A (VEGF-A)
Advanced MRI and Ultrasound in the Characterization of Peripheral Nerve Disorders Kliot, Michel
A Prospective, Randomized Controlled Trial Evaluating the Effectiveness of the Dolphin Bed versus Air Fluidized Systems in the Acute Post-Operative Management of Surgically Closed Pressure Ulcers Galiano, Robert D
A Study of the Efficacy and Safety of Etrolizumab in Ulcerative Colitis Patients Who Are Refractory to or Intolerant of TNF Inhibitors Hanauer, Stephen
A Prospective, Randomized, Comparative Effectiveness Study of a Single-Use, Negative Pressure Wound Therapy System (PICO) versus a Traditional Negative Pressure Wound Therapy System (tNPWT) in the Treatment of Lower Extremity Ulcers Galiano, Robert D
An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies Kaplan, Jason solid tumor, lymphoma, BET bromodomain inhibitor, BRD, Diffuse large B-cell lymphoma (DLBCL), Burkitt's lymphoma, c-MYC, colorectal cancer, Non-small cell lung cancer, Pancreatic adenocarcinoma, castration-resistant prostate cancer, breast cancer, NUT midline carcinoma, leukemia, acute myeloid leukemia (AML), atypical chronic myeloid leukemia (aCML), myelodysplastic syndrome (MDS), myeloproliferative neoplasms, myelofibrosis (MF), multiple myeloma (MM), CMML, MDS/MPN-U, RARS-T
Pertuzumab With High-Dose Trastuzumab in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (MBC) With Central Nervous System (CNS) Progression Post-Radiotherapy Kumthekar, Priya
Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation Altman, Jessica K Chondrosarcoma, Cholangiocarcinoma, Advanced Solid Tumors, Glioma, IDH1, IDH2, Dual Mutation, AG-881
An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies Kaplan, Jason
PACE - Patient-Centered Weight Loss Program for Knee Replacement Patients Pellegrini, Christine Knee replacement, weight loss, diet, physical activity
A Sacral Neuromodulation for Female Pelvic Floor Dysfunction Kielb, Stephanie J bowel symptoms, female pelvic pain, fecal incontinence, lower urinary tract symptoms, overactive bladder
Brighton: PNT2258 for Treatment of Patients With Richter's Transformation Kaplan, Jason PNT2258, Richter's Transformation, NHL, Non-Hodgkin's Lymphoma, Lymphoma, DLBCL, Diffuse Large B-cell Lymphoma, Lymphoma, Large B-cell, Diffuse, Lymphoma, Non-Hodgkin, Lymphoma, B-cell
Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae Resnick, Scott A
Functional Performance Evaluation of NU-FlexSIV Socket Fatone, Stefania prosthesis, prosthetic socket, transfemoral amputation, socket comfort, gait biomechanics
CompuFlo® Assessment Study for the Epidural Space Verification Peralta, Feyce
Study Evaluating the Efficacy and Safety of JCAR015 in Adult B-cell Acute Lymphoblastic Leukemia (B-ALL) Dinner, Shira acute lymphoblastic leukemia, ALL, chimeric antigen receptor, CAR, CAR T cells, JCAR015, autologous T cell therapy, cell therapy
A Prospective, Randomized, Single Center, Controlled Evaluation of the Effectiveness of OxyGenesysTM Topical Dissolved Oxygen Dressing in Accelerating the Healing of Split Thickness Skin Graft (STSG) Donor Sites Using the Northwestern University Abdominoplasty Scar Model Galiano, Robert D
JKB-121 for the Treatment of Nonalcoholic Steatohepatitis Rinella, Mary Eugenia NASH, Non-alcholic steatohepatitis, fatty liver disease
The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis Singhal, Seema
A Phase 3 Study to Examine the Efficacy, Safety and Tolerability of APL-130277 for the Acute Treatment of OFF Episodes in Patients With Parkinson's Disease Zadikoff, Cindy
Study of Pembrolizumab (MK-3475) as First-Line Monotherapy and Combination Therapy for Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (MK-3475-062/KEYNOTE-062) Benson III, Al B Gastric carcinoma, Gastric cancer, Gastroesophageal junction cancer, Gastroesophageal junction carcinoma, PD1, PDL1
Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients Taiwo, Babafemi O
Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis Rinella, Mary Eugenia Liver Cirrhosis
Preventing Anthracycline Cardiovascular Toxicity With Statins (PREVENT) Lee, Daniel C Stage I breast cancer, Stage II breast cancer, Stage III breast cancer
Efficacy and Safety of BI 655066 in Patients With Severe Persistent Asthma. Rosenberg, Sharon Reifler lungs, severe asthma, shortness of breath, chest tightness, coughing, risankizumab, breathing, pulmonary
A Prospective Study of Early Stage Breast Cancer Patients with Abnormal Myocardial Deformation treated with Anthracycline and/or Trastuzumab and Pertuzumab-based cancer therapy. Akhter, Nausheen Breast cancer, echocardiogram
A Study to Evaluate the Safety and Efficacy of Long Term Treatment With VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis Who Have an F508del-CFTR Mutation Jain, Manu
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061) Shulman, Lee P
Determination of ED90 of Intrathecal Lidocaine for Adequate Anesthesia for Elective Cervical Cerclage Surgery Toledo, Paloma Pain, Surgery, Pregnancy, Anesthesia
Skin Patch Sensors as a Substitute for Needle EMG Recordings to Detect Muscle Activity and Movement Dahdaleh, Nader
Standard of Care Therapy With or Without Stereotactic Radiosurgery and/or Surgery in Treating Patients With Limited Metastatic Breast Cancer Strauss, Jonathan B
Safety and Efficacy of GS-5745 in Participants With Moderately to Severely Active Crohn's Disease Hanauer, Stephen
Genomic Medicine at Northwestern: Discovery and Implementation in the eMERGE Network Smith, Maureen E
Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patients Using Levodopa Zadikoff, Cindy Motor fluctuations, Off time, On time, Dyskinesia
Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones Nadler, Robert B Kidney Stones, Nephrolithiasis, Urine Oxalate, Hyperoxaluria, Enteric Hyperoxaluria, Idiopathic Hyperoxaluria, Urological Diseases, Kidney Diseases, Dietary Oxalate
A Phase 3 Study of Tanezumab for Chronic Low Back Pain Schnitzer, Thomas J Chronic low back pain, Chronic pain
Healthy Hearts in the Heartland Kho, Abel N Preventive measures, Quality Improvement
Influenza Vaccine Responses as a Means of Assessing Immune Competence in Chimeric Kidney/Stem Cell Transplant Recipients Leventhal, Joseph R
Phase 1/2a Two-Arm Dose-Escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer Chae, Young Kwang
High Resolution and Functional MRI Assessment of Intracranial Atherosclerotic Plaque Ansari, Sameer Ahmad
A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/r With or Without Dasabuvir and With or Without Ribavirin in Chronic Hepatitis C Virus Genotype 1 or 4 Infected Adults With Successfully Treated Early Stage Hepatocellular Carcinoma Kulik, Laura M Chronic Hepatitis C Infection, Early Stage Hepatocellular Carcinoma
Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy Flamm, Steven L Chronic Hepatitis C Infection
Non-invasive Detection of Right Ventricular Interstitial Fibrosis using MRI in Patients with Pulmonary Hypertension due to Heart Failure with Preserved Ejection Fraction Freed, Benjamin
Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014) Wunderink, Richard G
Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a Year Sufit, Robert L fast skeletal troponin activator, tirasemtiv, CK-2017357, double-blind, randomized, placebo-controlled
Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy Agulnik, Mark
Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (NHL) Gordon, Leo I I JCAR017, chimeric antigen receptor, non-Hodgkin lymphoma, CAR, CAR T cells, autologous T cell therapy, cell therapy, NHL
Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease Molitch, Mark E Type 2 Diabetes, Kidney diseases
Nivolumab in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Cancer Agulnik, Mark
Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities Eskandari, Mark Rivaroxaban, Xarelto, Aspirin, Acetylic salicylic acid, Anticoagulant, Peripheral artery disease, Peripheral arterial disease, Revascularization, Acute limb ischemia, Amputation, Cardiovascular events
Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest) Peters, Anju Tripathi
Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 in Adults With Chronic HCV Infection Who Have Previously Received Treatment With Direct-Acting Antiviral Therapy Flamm, Steven L Chronic Hepatitis C Infection
Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164) Benson III, Al B PD1, PDL1, PD-L1
Study of N91115 in Patients With CF Homozygous for the F508del-CFTR Mutation Jain, Manu Cystic Fibrosis, N91115
Modeling Neuroscience for Enhancing Memory Operations through Non-Invasive Channels (MNEMONIC) Zee, Phyllis C
A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Subjects With Genotype 1 Infection Flamm, Steven L Chronic Hepatitis C, Hepatitis C Genotype 1 (GT1), IFN free, HCV GT1, Hepatitis C, Ribavirin Free, Non-cirrhotic, Interferon (IFN) Free, HCV, Hepatitis C virus, DAA, RBV Free, Without cirrhosis
Comparing the Efficacy and Safety of High-Titer Versus Low-Titer Anti-Influenza Immune Plasma for the Treatment of Severe Influenza A Ison, Michael G Anti-Influenza Immune Plasma
Walking Green: The Effects of Walking in Forested and Urban Areas on Health and Well-being Horton, Teresa Walking, Evanston
An Open-Label, Multicenter, Postmarketing, Milk-Only Lactation Study to Assess Concentration of Vedolizumab in Breast Milk of Lactating Women With Active Ulcerative Colitis or Crohn’s Disease Who Are Receiving Vedolizumab Therapeutically Stein, Adam Lactation, Lactating Women, Vedolizumab, Colitis Ulcerative, Crohn Disease, Crohn's, Inflammatory Bowel Diseases, Gastrointestinal Diseases, Digestive System Diseases, Colonic Diseases, Intestinal Diseases
The ENRGISE Pilot Study McDermott, Mary McGrae Douglas Mobility, Walking difficulty, Inflammation, Losartan, Omega-3 fish oil
Pravastatin for Prevention of Preeclampsia Wisner, Katherine preeclampsia, pravastatin, Pravachol®, statin, high-risk pregnancy, safety, fetal morbidity and mortality, maternal morbidity and mortality, neonatal mortality, premature delivery, preemie
A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung Fibrosis Dematte D'Amico, Jane E
An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation Frankfurt, Olga AG-221, CC-90007, Efficacy, Safety, Leukemia, Acute myloid meukemia, Isocitrate dehydrogenase 2 mutation
Vagus Nerve Stimulation Titration Protocol to Improve Tolerance and Accelerate Adaptation Macken, Micheal P Vagus Nerve Stimulation, ASCEND, VNS Titration to Improve Tolerance and Accelerate Adaptation
A PHASE I STUDY OF NEURAL STEM CELL BASED VIROTHERAPY IN COMBINATION WITH STANDARD RADIATION AND CHEMOTHERAPY FOR MALIGNANT GLIOMA Lesniak, Maciej malignant glioma, virotherapy, stem cells, newly diagnosed
(CIRB) A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis (NASH) Rinella, Mary Eugenia NASH, CIRRHOSIS, FATTY LIVER DISEASE
Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease Kalhan, Ravi Smoking, flare-ups, oxygen, shortness of breath, emphysema, chronic bronchitis
Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment Rinella, Mary Eugenia Non Alcoholic Steatohepatitis, fatty liver disease, NASH, liver fibrosis
Safety and Efficacy of SOF/VEL/GS-9857 FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor Flamm, Steven L Chronic
Safety and Efficacy of SOF/VEL/GS-9857 FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis Flamm, Steven L Chronic
A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO AND ACTIVE-CONTROLLED, MULTICENTER, PARALLEL-GROUP STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF TANEZUMAB IN ADULT SUBJECTS WITH CHRONIC LOW BACK PAIN Walega, David R chronic pain, low back pain
A Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of JNJ-63623872 in Combination With Oseltamivir in Adult, and Elderly Hospitalized Participants With Influenza A Infection Ison, Michael G Influenza A virus, JNJ-63623872, Oseltamivir
A Phase ll Study of IMM-124E for Patients With Non-alcoholic Steatohepatitis Rinella, Mary Eugenia NASH , Non-alcoholic steatohepatitis, fatty liver disease, Non-alcoholic Steatohepatitis, nonalcoholic steatohepatitis
Liver Test Study of Using JKB-122 in AIH Patients Flamm, Steven L AIH, JKB-122, autoimmune, hepatitis
A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain Schnitzer, Thomas J
PCR to Guide Antibiotic Therapy for Pneumonia Wunderink, Richard G Pneumonia, Methicillin-Resistant Staphylococcus aureus, Polymerase Chain Reaction, Intensive care units, Drug Resistance
Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor) Kircher, Sheetal Solid Tumors, MSB0010718C, Phase 1, Pharmacokinetic, anti PD-L1, Non-small cell lung cancer (NSCLC), Metastatic breast cancer (MBC), Gastric and gastroesophageal junction (GEJ) cancer, Ovarian cancer, Colorectal cancer (CRC), Castrate-resistant prostate cancer (CRPC), Melanoma, Urothelial carcinoma, Bladder cancer, Head and neck squamous cell carcinoma (HNSCC), Renal cell carcinoma (RCC), Adrenocortical carcinoma (ACC)
A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation Jain, Manu
Study of OTO-104 in Subjects With Unilateral Meniere's Disease Micco, Alan G Meniere's Disease, Vertigo
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Carneiro Filho, Benedito
Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes Davidson, Charles J TAVR, TAVI, Transfemoral aortic valve implantation, heart valve, Center for Heart Valve Disease, Center for Preventive Cardiology
COAST-1: Clinical Knee Osteoarthritis Symptom Treatment 1 Study A Randomized, Double-blind, Placebo-controlled Trial to Assess the Efficacy and Safety of AXS-02 (Disodium Zoledronate Tetrahydrate) Administered Orally to Subjects with Knee Osteoarthritis Associated with Bone Marrow Lesions. Schnitzer, Thomas J knee pain, knee, pain, osteoarthritis, knee osteoarthritis
(CIRB) A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial of IMO-8400 in Patients with Dermatomyositis Laumann, Anne E dermatomyositis
Effect of L-dopa In Subacute Back Pain Population Apkarian, Apkar Subacute, Back, Pain, Brain, MRI
Evaluating the Circadian Response to Light in Delayed Sleep-Wake Phase Disorder Abbott, Sabra circadian rhythm, sleep
First-in-Human Study of FLX925 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia Dinner, Shira
An Open-Label, First-in-Human Study of the Safety, Tolerability, and Pharmacokinetics of VX-970 in Combination With Cytotoxic Chemotherapy Gradishar, William J Solid Tumor, Advanced Solid Tumor
A Study of Coti-2 for the Treatment of Advanced or Recurrent Gynecologic Malignancies Nieves-Neira, Wilberto
A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification Kumthekar, Priya Newly Diagnosed Glioblastoma, Brain Tumor Group, Brain Tumor, Temozolomide, Radiology Therapy Oncology Group, ABT-414, EGFRvIII, Antibody Drug Conjugate, Epithelial Growth Factor Receptor
Nivolumab and Ipilimumab With or Without Sargramostim in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery Chandra, Sunandana
Comparison of Oral Octreotide Capsules to Injectable Somatostatin Analogs in Acromegaly Molitch, Mark E Octreotide Capsules, Acromegaly, Somatostatin, Mpowered, OOC-ACM-302
Dose Escalation Study of QR-010 in Homozygous ΔF508 Cystic Fibrosis Patients Jain, Manu cystic fibrosis, ΔF508, RNA therapies, antisense oligonucleotide, CFTR, F508del, CF, RNA therapy
Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass Pham, Duc Thinh coronary artery bypass grafting, CABG, mitral valve, LCOS, low cardiac output syndrome, levosimendan
Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Goldstein, Debra Uveitis, UME, Posterior Uveitis, Anterior Uveitis, Intermediate Uveitis, Panuveitis, Non-infectious Uveitis, Triamcinolone, Choroid, Choroidal Injection, Suprachoroidal, Microneedle, Microinjection
Rapidity of Response to Adalimumab Treatment in Patients With Crohn´s Disease Hanauer, Stephen Crohn's Disease
MEDI4736 (Anti PD-L1) Combined With Gefitinib in Subjects With Non-Small Cell Lung Cancer(NSCLC) Chae, Young Kwang NSCLC
Glembatumumab Vedotin in Treating Patients With Metastatic or Locally Recurrent Uveal Melanoma Chandra, Sunandana
A Phase 2b, Open-Label Study of 200 mg or 400 mg Sofosbuvir+RBV for 24 Weeks in Genotype 1 or 3 and Ledipasvir/Sofosbuvir (LDV/SOF) Fixed-Dose Combination (FDC) Tablet for 12 weeks in Genotype 1 or 4 HCV-Infected Subjects with Renal Insufficiency Flamm, Steven L Hepatitis C, Renal Insufficiency, Harvoni
Establishing a methodology to assay CO in peripheral human blood Wisner, Katherine
A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors Nieves-Neira, Wilberto advanced solid tumors; immunotherapy; OX40; immuno-oncology
Molecular Biomarkers of Improvement for Patients with Systemic Sclerosis Hinchcliff, Monique E systemic sclerosis, scleroderma, genetics, gene expression, healthy controls, biomarkers
Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease Ansari, Sameer Ahmad Intracranial Atherosclerotic Disease, Stroke, Transient Ischemic Attack, Imaging
High-Dose Recombinant Interferon Alfa-2B or Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery Chandra, Sunandana
A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor Peaceman, Alan M Spontaneous Preterm Labor, GSK221149, Retosiban
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation Jain, Manu
Study to Evaluate Multiple Doses in Patients With Nasal Polyposis Peters, Anju Tripathi
A Phase 1 Dose-Ranging Study to Investigate the Safety, Tolerability, and Pharmacokinetics of MRG-106 following Local Intratumoral and Subcutaneous Injection in Patients with Cutaneous T-cell Lymphoma (CTCL), Mycosis Fungoides (MF) Sub-Type Guitart, Joan cutaneous lymphoma, CTCL, Mycosis Fungoides, MF , MRG-106
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK1/2/3, ROS1, or ALK Gene Rearrangements (Fusions) Chae, Young Kwang Entrectinib, RXDX-101, TrkA, TrkB, TrkC, NTRK1, NTRK2, NTRK3, ROS1, ALK, Trk Fusions, NTRK Gene Rearrangements, ROS1 Fusions, ROS1 Gene Rearrangements, ALK Fusions, ALK Gene Rearrangements, Basket study, Non-small cell lung cancer, Colorectal cancer, Salivary gland cancers, Primary brain tumors, Melanoma, Sarcomas, Papillary thyroid cancer, Renal cell cancer, Pancreatic cancer, Breast cancer, Cholangiocarcinoma, Head & Neck cancers, Ovarian cancer, Neuroendocrine tumors, Anaplastic Large Cell Lymphoma
[Trial of device that is not approved or cleared by the U.S. FDA] Wolfe, Lisa F
Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck Agulnik, Mark Recurrent Metastatic Squamous Cell Carcinoma Head and Neck
Study of Gelesis100 on Body Weight in Overweight and Obese Subjects With and Without Type 2 Diabetes Kushner, Robert F
Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers Taiwo, Babafemi O
Efatutazone With Paclitaxel Versus Paclitaxel Alone in Treating Patients With Advanced Anaplastic Thyroid Cancer Matsangou, Maria
A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus Ramsey-Goldman, Rosalind
13C-Methacetin Breath Test for the Prediction of Outcome in Acute Liver Failure Ganger, Daniel R Acute liver failure
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer Gradishar, William J
A Study of GC4419 Protection Against Radiation Induced Oral Mucositis in Patients With Head & Neck Cancer Matsangou, Maria squamous cell carcinoma of the head and neck, oral cavity, oropharynx, intensity-modulated radiation therapy, chemotherapy, oral mucositis, superoxide dismutase, radioprotection
Cocoa to Improve Walking Performance in Peripheral Artery Disease: The COCOA-PAD Study McDermott, Mary McGrae Douglas peripheral artery disease, cardiovascular disease, cocoa, atherosclerosis
Safety and Efficacy of CRS-207 With Epacadostat in Platinum Resistant Ovarian, Fallopian, or Peritoneal Cancer Matei, Daniela Ovarian cancer, Fallopian cancer, Primary peritoneal cancer
A Double Blind, Randomized, Vehicle Controlled, Crossover Study to Evaluate the Safety and Efficacy of Topical Naloxone Hydrochloride Lotion 0.5% for the Relief of Pruritus in Patients with the Mycosis Fungoides (MF) Form of Cutaneous T-Cell Lymphoma (CTCL) Guitart, Joan mycosis fungoides, MF, Cutaneous T Cell Lymphoma, CTCL , Naloxone
Margetuximab Plus Chemotherapy vs Trastuzumab Plus Chemotherapy in the Treatment of HER2+ Metastatic Breast Cancer Gradishar, William J
A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE) Kumthekar, Priya rGBM, Recurrent Glioblastoma, Recurrent GBM
Neural pathways underlying discrimination and generalization in associative learning Kahnt, Thorsten
A Study To Confirm Efficacy and Safety of Terlipressin in HRS Type 1 Ganger, Daniel R Hepatorenal Syndrome Type 1
P03277 Dose Finding Study in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) Liu, Benjamin P03277, CNS lesions, Multihance, dose finding
A Study Looking at Targeted Therapy According to Tumor Markers for People With Meningiomas Kumthekar, Priya
A Phase II Study of Pembrolizumab (MK-3475) as Monotherapy in Subjects with Previously Treated Locally Advanced Unresectable or Metastatic (Stage IV) Mismatched Repair Deficient or Microsatellite Instability-High Colorectal Carcinoma (KEYNOTE-164) Benson III, Al B
(CIRB) A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Elafibranor in Patients with Nonalcoholic Steatohepatitis (NASH) and fibrosis Rinella, Mary Eugenia NASH and Fibrosis
Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma Gordon, Leo I I
Pulmonary Fibrosis Foundation Patient Registry Bhorade, Sangeeta
A STUDY OF THE EFFICACY AND SAFETY OF BARDOXOLONE METHYL IN PATIENTS WITH CONNECTIVE TISSUE DISEASE-ASSOCIATED PULMONARY ARTERIAL HYPERTENSION VERSION 1.0 – 27 JAN 2016 Cuttica, Michael J Pulmonary Hypertension Pulmonary Arterial Hypertension Connective Tissue Disease-Associated Pulmonary Arterial Hypertension Bardoxolone methyl
A Multicenter, Randomized, Double-Blind, Placebo- Controlled Trial of Emricasan (IDN-6556), an Oral Caspase Inhibitor, in Subjects with Non-alcoholic Steatohepatitis (NASH) Fibrosis Rinella, Mary Eugenia NASH, fatty liver disease
AHA Strategically Focused Research Network: mHealth Intervention to Preserve and Promote Ideal Cardiovascular Health-Study 2 Spring, Bonnie College student, cardiovascular health
Northwestern Scleroderma Twins Registry and Biorepository Varga, John twins, scleroderma, systemic sclerosis, genetics, epigenetics, genes
Multidisciplinary Treatment for Obstructive Sleep Apnea and Insomnia Ong, Jason C OSA, Obstructive sleep apnea, insomnia, CBT, CBT-I, CPAP, Sleep study, sleep disorders
Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Agulnik, Mark
(CIRB) A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-0976 in Subjects with Nonalcoholic Steatohepatitis Rinella, Mary Eugenia fatty liver disease
ACTG A5354: Effect of Antiretroviral Treatment Initiated During Acute HIV-1 Infection on Measures of HIV-1 Persistence and on HIV-1-Specific Immune Responses Taiwo, Babafemi O acute infection , HIV infection, antiretroviral treatment
A Multicenter, Open-label, Single-Arm Study to Evaluate the Contraceptive Efficacy and Safety of a Combined Oral Contraceptive Containing 15 mg Estetrol and 3 mg Drospirenone Shulman, Lee P Contraceptive, birth control, women
Alzheimer’s Disease Neuroimaging Initiative 3 Rogalski, Emily Joy
SMART: A prospective, multi-center registry assessing the embolization of neurovascular lesions using the Penumbra SMART COIL® System Hurley, Michael
Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma Gordon, Leo I I
Chicago Adolescent Longitudinal Study Reilly, James Young Adult, Adult, MRI, Brain imaging, Bipolar, Bipolar Type 1, Bipolar Type 2, Schizophrenia, Schizoaffective, Depression, Imaging
Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta Hoel, Andrew Aortic Aneurysm, Aortic Dissection, Intramural Hematoma, Aortic Disease, Aortic Injury
Study in Recipients of Renal Transplant Allograft to Evaluate the Impact of Two Immunosuppressive Regimens Gallon, Lorenzo transplant, kidney, renal disease
Repetitive Transcranial Magnetic Stimulation in Breast Cancer Patients With Depression and Anxiety Dokucu, Mehmet E repetitive Transcranial Magnetic Stimulation, Breast Cancer Survivor, Depression, Anxiety, rTMS
Mild Cognitive Impairment in Breast Cancer Patients Wang, Lei breast cancer, invasive ductal carcinoma, DCIS, ductal carcinoma in situ, cognitive impairment, adjuvant therapy, hormone therapy, hormonal therapy, chemotherapy, chemo brain, MRI, brain, cognition
Mobile Monitoring for Long Term Behavioral Data Collection in Bipolar Disorder Goulding, Evan Mobile, Cell Phone, Bipolar, Bipolar Type 1, Bipolar Type 2, Relapse, Mobile Applications, Apps
Phase 1b Acute Myelogenous Leukemia (AML) Study With ABT-199 + Decitabine or Azacitidine (Chemo Combo) Frankfurt, Olga GDC-0199, Myelogenous Leukemia, Untreated AML, ABT-199, Treatment Naive AML, AML, Acute Myelogenous Leukemia
Evaluating the Use of Pitavastatin to Reduce the Risk of Cardiovascular Disease in HIV-Infected Adults Taiwo, Babafemi O HIV, Cardiovascular Disease, Myocardial Infarction, Inflammation, Statin, heart disease
NEUROLOGICAL MECHANISMS OF TREATMENT PROJECT (NMT): AN EXAMINATION OF THE NEUROLOGICAL EFFECTS OF COGNITIVE BEHAVIORAL THERAPY ON ADOLESCENTS WITH DEPRESSION Breiter, Hans Depression, Young adult, Adolescent, Therapy, Cognitive Behavioral Therapy, CBT, Cognitive Therapy, MDD, Major Depressive Disorder
Effect of Magnesium Threonate (MgT) on Cognitive Enhancement in Schizophrenia Meltzer, Herbert Schizophrenia, Schizoaffective disorder, Cognition, Magnesium, Imaging, Negative symptoms, Clinical Trial, Memory, Investigational Drug, Medication
Study of SD-101 in Combination With Localized Low-dose Radiation in Patients With Untreated Low-grade B-cell Lymphoma Gordon, Leo I I Low Grade B-cell Lymphoma
Testing the Ability of JNJ-18038683 to Improve Cognition and Reduce Depressive Symptoms in Stable Bipolar Patients Meltzer, Herbert Bipolar, Depression, Cognition, Cognitive, Mood, Memory, Investigational Drug, Mania, Hypomania, Bipolar Type 1, Bipolar Type 2, Clinical Trial
Optimizing Medication Management for Mothers with Depression (OPTI-MOM) Wisner, Katherine pregnancy, depression, psychiatry, psychology, mental health, postpartum, ssri, anti-depressant, antidepressant, prozac, zolof, celexa, lexapro, pregnant
Comparison of a Long-acting Injectable Antipsychotic vs Clinician's Choice Early in Treatment to Break the Cycle of Relapse in Early Phase Schizophrenics Rado, Jeffrey First Episode, Recent Onset, Schizophrenia, Cognition, Magnesium, Imaging, Clinical Trial, Memory, Investigational Drug, Medication, MRI
Culturally Adapted Cognitive Behavioral Stress and Self-Management (C-CBSM) Intervention for Prostate Cancer Penedo, Frank J Prostate Cancer, Relaxation Techniques, Hispanic male, Spanish, Stress Management, hispanic, latino, hombres, espanol, cancer de prostata
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Subjects with Nonalcoholic Steatohepatitis (NASH) Rinella, Mary Eugenia NASH
A Randomized Trial of Pessary in Singleton Pregnancies with a Short Cervix (TOPS) Grobman, William A preterm delivery, arabin pessary, short cervix
Northwestern University The Department of Psychiatry and Behavioral Sciences, Clinical Research Program (NU CRP) Recruitment Pipeline Goldman, Morris B Schizophrenia, Schizoaffective, Depression, Anxiety, Bipolar, Bipolar Type 1, Bipolar Type 2, Mania, Hypomania, Major Depressive Disorder, Mood, Cognition, Research Study, Adult, Adolescent, Children, Alzheimer's disease, Clinical Trial, Non Clinical Trial, Therapy, Investigational Drug, Post Traumatic Stress Disorder
Open-label safety trial of intravenous neridronic acid in subjects with complex regional pain syndrome (CRPS) Schnitzer, Thomas J CRPS, neridronic, acid, complex regional pain syndrome, complex, regional, pain, syndrome, reflex sympathetic dystrophy, RSD
Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation Altman, Jessica K acute myeloid leukemia, AML, myelodysplastic syndrome, MDS, hematologic malignancies, IDH, Untreated AML, ≥60 Years of Age and Not a Candidate for Standard Therapy
Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas Kaplan, Jason
Development of a non-invasive prenatal screening test for multiple gestation pregnancies based on fetal DNA isolated from maternal blood Robins, Jared multiple gestation, twins, triplets, non-invasive prenatal diagnostic test, genetic testing, NIPT
Folic Acid and Zinc Supplementation Trial (FAZST) Robins, Jared Folic Acid, Zinc, Semen, In vitro fertilization, Assisted reproductive technology, Ovulation induction, Intrauterine insemination, Pregnancy, Live Birth, IUI, IVF, Assisted reproduction technology, Fertility, Infertility
Prospective Multicenter Cohort Study Comparing Extent of Tumor Resection Between Microscopic Transsphenoidal Surgery and Fully Endoscopic Transsphenoidal Surgery for Nonfunctioning Pituitary Adenomas [Transsphenoidal Extent of Resection Study – TRANSSPHER Study] Chandler, James P pituitary, transsphenoidal surgery
A Randomized Trial of Induction Versus Expectant Management Grobman, William A First time moms, induction, expectant management, group assignment, singleton pregnancy
Multi-Center Clinical Feasibility Evaluation of the Access AMH Assay to Measure AMH as an Aid in the Prediction of Poor Ovarian Response to Controlled Ovarian Stimulation Pavone, MaryEllen Ellen AMH, infertility, IVF, ovarian reserve, anti-Mullerian hormone
Is a Chance to Cut a Chance to Heal? A Pilot Study to Determine the Role of Submucosal Fibroids in Endometrial Gene Expression and Function Bernardi Wendeln, Lia fibroids, uterus, menstrual bleeding, miscarriage
Prevalence of aneuploidy in ectopic pregnancies Feinberg, Eve ectopic pregnancy, genetic testing, aneuploidy, infertility, fertility, pathology
Multi-Center Clinical Evaluation of the Access AMH Assay to Measure AMH as an Aid in the Prediction of Poor Ovarian Response to Controlled Ovarian Stimulation Pavone, MaryEllen Ellen AMH, anti-Mullerian hormone, IVF, ovarian reserve, fertility, infertility, in vitro fertilization
RELIEF: A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain (A7007) Rosenow, Joshua M neurostimulation, chronic pain
Precision Retrospective Outcomes (PRO) Rosenow, Joshua M neurostimulation, spinal cord stimulation
STING (Study of Immunotherapy in Newly Diagnosed Glioblastoma): A Phase III randomized double-blind, controlled study of ICT-107 with maintenance temozolomide (TMZ) in newly diagnosed glioblastoma following resection and concomitant TMZ chemoradiotherapy Chandler, James P glioblastoma, dendritic cells, vaccine
A Randomized, Double-Blinded, Placebo-Controlled, Multicenter Pilot Study of the SPRINT Peripheral Nerve Stimulation (PNS) System for the Treatment of Post-Amputation Pain Rosenow, Joshua M Amputee, peripheral nerve stimulation
rTMS: A Treatment to Restore Function After Severe TBI Pape, Theresa L Bender L Transcranial Magnetic Stimulation, traumatic brain injury
Cardiovascular Outcomes Assessment of the MitraClip Therapy Percutaneous Therapy for High Surgical Risk Patients Ricciardi, Mark mitral regurgitation , center for valve disease, valve, heart failure, center for heart failure, coapt, mitraclip
Chemokine mechanisms in chronic pelvic pain Thumbikat, Praveen Pelvic pain, genitourinary pain , prostatitis
MAST CELLS IN MALE CHRONIC PELVIC PAIN AND LOWER URINARY TRACT DYSFUNCTION Thumbikat, Praveen chronic prostatitis, chronic pelvic pain syndrome, prostatitis, male pelvic pain
A Study of CLR325 in Chronic Stable Heart Failure Patients. Wilcox, Jane Elizabeth Heart Failure, CLR325, Center for Heart Failure
A Randomized, Double-Blind, Placebo-Controlled Phase 4 Study to Evaluate the Efficacy and Safety of Entyvio (Vedolizumab IV) in the Treatment of Chronic Pouchitis (EARNEST) Baidoo, Leonard Drug Therapy , Pouchitis , Vedolizumab , Colitis, ulcerative , ulcerative colitis , Gastrointestinal Diseases, Inflammatory Bowel Diseases, Colonic Diseases, Intestinal Diseases
A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Effectiveness of a Nutritional Intervention in Improving the Intestinal Mucosal Health Status in Subjects with Crohn’s Disease (CD) Receiving Anti-TNF Therapy (PIONEER-CD) Hanauer, Stephen Crohn's Disease , Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases, mucosal healing, inflammatory bowel disease, Medical Food , Crohn Disease
A Phase I Study to Evaluate the Safety, Tolerability and Efficacy of MEDI4736 With Tremelimumab or Tremelimumab Alone in Head and Neck Cancer Agulnik, Mark
A Randomized Double-Blind Phase 4 Study to Evaluate the Safety and Proportion of Subjects With Fistula Healing in 2 Dose Regimens of Entyvio (Vedolizumab IV) in the Treatment of Fistulizing Crohn’s Disease (ENTERPRISE) Baidoo, Leonard Crohn Disease , Crohn's Disease , Inflammatory Bowel Diseases , Gastroenteritis, Gastrointestinal Diseases , Digestive System Diseases, Intestinal Diseases, Vedolizumab, Gastrointestinal Agents
HOme-based moNitORed exercise for PAD McDermott, Mary McGrae Douglas peripheral artery disease; , PAD, leg pain, walking difficulty
Improve PAD PERformance with METformin: The PERMET Trial McDermott, Mary McGrae Douglas peripheral artery diease, peripheral arterial disease, leg pain , walking difficulty
The Safety and Effectiveness of the VaricElla zosteR VaccinE (VERVE) in Anti-TNF Users Hanauer, Stephen Vaccines , crohn's disease , Arthritis , Inflammatory Bowel Diseases , Gastroenteritis , Gastrointestinal Diseases , Digestive System Diseases , Intestinal Diseases
BI 695501 versus Humira® in patients with active Crohn’s disease: a randomized, double-blind, multicenter, parallel group, non-inferiority trial comparing efficacy, endoscopic improvement, safety, and immunogenicity Hanauer, Stephen Crohn Disease , Crohn's Disease , Inflammatory Bowel Diseases , Gastroenteritis , Gastrointestinal Diseases , Digestive System Diseases , Intestinal Diseases , Adalimumab , Anti-Inflammatory Agents , Antirheumatic Agents
A Phase 2, Multicenter, Randomized, Double-Blind, Parallel, Placebo-Controlled Study of LY3074828 in Subjects with Moderate to Severe Ulcerative Colitis Hanauer, Stephen IL-23 antibody , Colitis, Ulcerative, ulcerative colitis, Gastroenteritis , Gastrointestinal Diseases, Digestive System Diseases, Colonic Diseases, Intestinal Diseases, Pathologic Processes, Inflammatory Bowel Diseases
AdreView™ Myocardial Imaging for Risk Evaluation – A multicentre trial to guide ICD implantation in NYHA class II & III heart failure patients with 25%≤LVEF≤35%. Wilcox, Jane Elizabeth Heart Failure, ICD, Nuclear Medicine
Risk Stratification in Older Persons with Acute Myocardial Infarction: SILVER-AMI Mikati, Issam A Center for Coronary Disease, Heart Disease, heart attack, MI
SUSTAIN-IT: Sustaining quality of life of the aged: Heart transplant or mechanical support? Grady, Kathleen L L. Center for Heart Failure, MCS, mechanical circulatory support, transplant, VAD
MOMENTUM 3 IDE Clinical Study Protocol Anderson, Allen Heart Failure, Left Ventricular Assist Device, Ventricular Dysfunction, Cardiomyopathy, Heart Disease, Cardiovascular Disease, Heart-assist devices, center for heart failure, LVAD
ACUpuncture after HEART Surgery Feingold, Kim R accupuncture, Center for Preventive Cardiology
HFN - CHART Shah, Sanjiv J Heart Failure, Diastolic Dysfunction, HIV, HAART
Long-Term Nicotine Treatment of Mild Cognitive Impairment Grant, Ian Mild Cognitive Impairment, Alzheimer's disease
Impact of Hemodynamic Ramp Test-Guided HVAD RPM and Medication Adjustments on Exercise Tolerance and Quality of Life: A Multicenter Study Rich, Jonathan LVAD, Center for Heart Failure, Heart Failure, left ventricular assist device , Echocardiography
Early Feasibility Study of the CardiAQ™ Transcatheter Mitral Valve Implantation (TMVI) System (Transseptal and Transapical Delivery Systems) For the Treatment of Moderate to Severe Mitral Regurgitation Davidson, Charles J mitral valve regurgitation, MR, TMVI, TMVR , Center for Heart Valve Disease
Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia Eskandari, Mark Surgical revascularization, Endovascular revascularization, Amputation, Center for Vascular Disease, CLI , limb ischemia
Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System McCarthy, Patrick M Mitral, Regurgitation, Heart valve, Transcatheter, Transapical, Functional, Degenerative, Symptomatic, severe mitral valve regurgitation, high risk for open mitral valve surgery, Center for Heart Valve Disease
A Randomized Phase II Study of Topical Steroids as Preemptive Therapy for Epidermal Growth Factor Receptor Inhibitor-Induced Papulopustular Eruption Choi, Jennifer epidermal growth factor inhibitor , egfr inhibitor , acneiform rash, papulopustular eruption , drug rash, topical steroid cream
Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Rich, Stuart percutaneous, tricuspid , tricuspid regurgitation, valve, Center for Heart Valve Disease
aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation Lin, Albert LAA, Left Atrial Appendage, Lariat , PVI , ablation , Center for Heart Rhythm Disorders
The Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis Malaisrie, S Chris Chris Center for Heart Valve Disease, Aortic Valve, Aortic Stenosis, AVR, TAVR, transcatheter , PARTNER, PARTNER 3, SAPIEN, THV
A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Aortic Bioprosthetic Valve Malaisrie, S Chris Chris TAVR, Aortic Valve Replacement , Aortic Stenosis, PARTNER, PARTNER 3, valve in valve
Propofol Versus Sevoflurane Recovery After Gynecological Surgery De Oliveira, Gildasio S Outpatient, Surgery, Anesthesia
Minimum interference human-in-the-loop interfaces for task-specific performance and training Dewald, Julius P P robotics, motor learning, virtual
LURN: Symptoms of Lower Urinary Tract Dysfunction Research Network Prospective Phenotyping Study Cella, David
Technology-based Psychosocial Intervention for Symptom Management & HRQOL in Men Living with Advanced Prostate Cancer Penedo, Frank J
Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery De Oliveira, Gildasio S Outpatient, Surgery, Breast, Pain
Acute Extravascular Defibrillation, Pacing and Electrogram Study (ASD2) Knight, Bradley Paul
A Phase I Study of Ad-RTS-hIL-12, an Inducible Adenoviral Vector Engineered to Express hIL-12 in the Presence of the Activator Ligand Veledimex in Subjects With Recurrent or Progressive Glioblastoma or Grade III Malignant Gliomas Lesniak, Maciej malignant brain tumor, glioblastoma, viral vector
EFFECTS OF DAPAGLIFLOZIN ON BIOMARKERS, SYMPTOMS AND FUNCTIONAL STATUS IN PATIENTS WITH TYPE 2 DIABETES OR PRE-DIABETES, AND PRESERVED EJECTION FRACTION HEART FAILURE (PRESERVED-HF TRIAL) Khan, Sadiya Heart Failure, T2DM, Type 2 Diabetes, prediabetes, diabetes, HFpEF
Department of Psychiatry and Behavioral Sciences Research Registry Goldman, Morris B
Performance of Kardia / Apple Watch in Detecting and Quantifying Atrial Fibrillation Passman, Rod S Atrial Fibrillation , Rhythm disorders, Kardia Band
AMPLATZER™ Amulet™ Left Atrial Appendage (LAA) Occluder Randomized Controlled Trial Knight, Bradley Paul Atrial Fibrillation, Left Atrial Appendage, LAA
Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis: EARLY TAVR trial Davidson, Charles J Aortic Stenosis, TAVR, Aortic Valve Disease, PARTNER, EARLY TAVR, SAPIEN, THV
(CIRB) A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib in Subjects with Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis Rinella, Mary Eugenia NASH, Fibrosis, Fatty liver disease
CardioMEMS HF System Post Approval Study Anderson, Allen Heart Failure, CardioMEMS
Evaluation of the Safety and Performance of The Twelve Intrepid™ Transcatheter Mitral Valve Replacement System in High Risk Patients with Severe, Symptomatic Mitral Regurgitation - The Twelve Intrepid™ TMVR Pilot Study McCarthy, Patrick M Valve Disease, TMVR, Mitral Valve, Mitral Regurgitation, Transcatheter
A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1 Schnitzer, Thomas J CRPS , RSD, Pain
Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip Schnitzer, Thomas J
Bump on the Ball: Impact of a Prenatal Exercise & Education Program on Birth Outcomes & Maternal Quality of Life Gaupp, Christina Lewicky singleton pregnancy, second trimester, pregnancy exercise, pregnancy fitness, pregnancy education
Sacral Neuromodulation in Dual Incontinence: Ultrasound and Afferent Nerve Sensation Assessment (SaNDI) Kenton, Kimberly dual incontinence, nerve stimulation
Permanent versus delayed-absorbable monofilament suture for vaginal graft attachment during minimally-invasive total hysterectomy and sacrocolpopexy: A Randomized Clinical Trial Kenton, Kimberly permanent stitches, delayed absorbable stitches, pelvic organ prolapse, uterus removal
Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee Schnitzer, Thomas J knee pain, hip pain, osteoarthritis, pain
VESPR: Vaginal Electrical Stimulation for Postpartum neuromuscular Recovery Gaupp, Christina Lewicky vaginal tear, obstetric tear, vaginal electrical stimulation, stimulation, pregnancy , postpartum
The association between the urinary microbiome and response to sacral neuromodulation in women with urgency urinary incontinence Mueller, Margaret urinary bacteria , nerve stimulation, overactive bladder
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF THE ANALGESIC EFFICACY AND SAFETY OF A DOSE TITRATION REGIMEN FOR THE SUBCUTANEOUS ADMINISTRATION OF TANEZUMAB IN SUBJECTS WITH OSTEOARTHRITIS OF THE HIP OR KNEE Schnitzer, Thomas J osteoarthritis , hip pain , knee pain, pain
Postpartum GRANulation Tissue: The GRANT Study Gaupp, Christina Lewicky granulation tissue, postpartum recovery, obstetric tear
Fibroids and Urinary Symptoms Study (FUSS) Survey Kenton, Kimberly fibroids, pelvic floor, urinary symptoms, uterine fibroids, MRI
REDUCE LAP-HF RANDOMIZED TRIAL II: A study to evaluate the Corvia Medical, Inc. IASD® System II to REDUCE Elevated Left Atrial Pressure in Patients with Heart Failure Ricciardi, Mark heart failure
Specimen and Data Study for Ovarian Cancer Early Detection and Prevention Shulman, Lee P ovarian epithelial cancer, hereditary breast/ovarian cancer (BRCA1, BRCA2), fallopian tube cancer, ovarian germ cell tumor, ovarian sarcoma, ovarian stromal cancer, endometrial cancer, uterine sarcoma, vaginal cancer, cervical cancer, vulvar cancer, uterine leiomyomata
Morning Light Treatment at Home to Improve Glucose Metabolism in People at Increased Risk for Type 2 Diabetes Knutson, Kristen prediabetes, morning light treatment, sleep, circadian misalignment
A Maintenance Study With Niraparib Versus Placebo in Patients With Platinum Sensitive Ovarian Cancer Nieves-Neira, Wilberto ovarian cancer, platinum sensitive, gBRCAmut, BRCA, high-grade serous histology, PARP inhibitor
Gemcitabine Hydrochloride and Cisplatin With or Without Radiation Therapy in Treating Patients With Localized Liver Cancer That Cannot Be Removed By Surgery Hayes, John P
NCI 2015-06-04 Phase IIB trial of neoadjuvant oral tamoxifen versus transdermal 4-hydroxytamoxifen in women with DCIS of the breast Khan, Seema Ahsan Ahsan
A Study of Niraparib in Patients With Ovarian Cancer Who Have Received at Least Three Previous Chemotherapy Regimens Nieves-Neira, Wilberto gBRCAmut, BRCA, PARP inhibitor, HRD, Ovarian cancer, Serous Epithelial, Fallopian Tube, Primary Peritoneal
An Extension Study to Evaluate Maintenance of Efficacy and Long-term Treatment Effect of Oral Budesonide Suspension (OBS) in Adults and Adolescents With Eosinophilic Esophagitis (EoE) Hirano, Ikuo
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer Flaum, Lisa estrogen receptor-positive breast cancer, HER2-negative breast cancer, stage IA breast cancer, stage IB breast cancer, stage II breast cancer, stage IIIA breast cancer, stage IIIB breast cancer, stage IIIC breast cancer, progesterone receptor-positive breast cancer, male breast cancer
First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma Hussain, Maha
MULTIETHNIC FINE-MAPPING OF POLYCYSTIC OVARY SYNDROME SUSCEPTIBILITY LOCI (R01 HD085227) Dunaif, Andrea E Polycystic Ovary Syndrome, PCOS , Infertility, Ovary, Endocrine Disorder, Irregular Periods, Acne, Metformin , Spironolactone, Overweight, Obese
Trial of CMB305 and Atezolizumab in Patients With Sarcoma Agulnik, Mark immunotherapy, CMB305, LV305, GLA-SE, Atezolizumab, NY-ESO-1
A Study of ACP-196 (Acalabrutinib) in Subjects With Relapsed/Refractory CLL and Intolerant of Ibrutinib Therapy Ma, Shuo Chronic Lymphocytic Leukemia, Ibrutinib Intolerant
Clinician-input study: how the Fox Insight mobile application can influence treatment and care (CIS-PD) Simuni, Tatyana parkinson's disease, PD, wearable technology, Iphone, apple watch
Assessment of the WATCHMAN(TM) Device in Patients Unsuitable for Oral Anticoagulation Knight, Bradley Paul atrial fibrillation, afib, anticoagulation, heart rhythm disorders
Sunitinib Malate With or Without Gemcitabine Hydrochloride in Treating Patients With Advanced Kidney Cancer That Cannot Be Removed By Surgery Sosman, Jeffrey recurrent renal cell cancer, stage IV renal cell cancer, clear cell renal cell carcinoma, papillary renal cell carcinoma, clear cell sarcoma of the kidney
Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery Sosman, Jeffrey
Exemestane With or Without Entinostat in Treating Postmenopausal Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic Gradishar, William J
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Investigate The Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Subjects with Active Crohn's Disease. Hanauer, Stephen Crohn's Disease , GED-0301 , Mongersen , IBD , Crohn Disease , Inflammatory Bowel Diseases , Gastroenteritis , Digestive System Diseases , Gastrointestinal Diseases , Intestinal Diseases
Phase IIB TL + YCWP + DC in Melanoma Chandra, Sunandana
A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma Agulnik, Mark
Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer Matei, Daniela Cancer, Recurrent, Ovary, Fallopian Tube, Primary Peritioneal, Phase II, Platinum Resistant
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial) Mohindra, Nisha
A Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Assess the Efficacy and Safety of Oral GKT137831 in Patients with Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid and with Persistently Elevated Alkaline Phosphatase Flamm, Steven L PBC
A Double-Blind, Controlled Phase 2 Study of the Safety and Efficacy of Modified Stem Cells (SB623) in Patients with Chronic Motor Deficit from Traumatic Brain Injury (TBI) Rosenow, Joshua M Traumatic brain injury, stem cells
Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Cholangiocarcinoma Benson III, Al B Advanced Cholangiocarcinoma, Metastatic Cholangiocarcinoma, CCA, Bile Duct Cancer, Nab-Paclitaxel, Abraxane®, Gemcitabine, Gemzar®
Genomic Response Analysis of Heart Failure Therapy in African Americans Anderson, Allen heart failure
PRevalence Of Microvascular dySfunction in Heart Failure with Preserved Ejection Fraction Shah, Sanjiv J heart failure, pulmonary hypertension, HFpEF, preserved ejection fraction
SDF1 Plasmid Treatment for Patients With Peripheral Artery Disease Ho, Karen Center for Vascular Disease, PAD, peripheral artery disease
The Effect of KNO3 Compared to KCl on Oxygen Uptake in Heart Failure with Preserved Ejection Fraction Shah, Sanjiv J heart failure, HFpEF, preserved ejection fraction, exercise
Evaluation of the Thoraflex™ Hybrid Device for Use in the Repair or Replacement of the Ascending Aorta, Aortic Arch and Descending Aorta in an Open Surgical Procedure. Protocol #: Hybrid-002 Malaisrie, S Chris Chris aorta, vascular disease, valve disease, aneurysm
A Phase 3 Randomized, Double-Blind, Multi-Dose, Placebo and Naproxen-Controlled Study to Evaluate the Efficacy and Safety of Fasinumab in Patients with Pain Due to Osteoarthritis of the Knee or Hip Schnitzer, Thomas J arthritis, osteoarthritis, knee pain, hip pain, pain management, pain
Inorganic Nitrite Delivery to Improve Exercise Capacity in HFpEF Shah, Sanjiv J heart failure, exercise capacity
A PHASE 3, PLACEBO CONTROLLED, DOUBLE-BLIND, RANDOMIZED, CLINICAL STUDY TO DETERMINE EFFICACY, SAFETY AND TOLERABILITY OF PULSED, INHALED NITRIC OXIDE (iNO) VERSUS PLACEBO IN SYMPTOMATIC SUBJECTS WITH PULMONARY ARTERIAL HYPERTENSION (PAH): INOvation-1 Rich, Stuart pulmonary arterial hypertension, PAH, heart failure
A Randomized, Double-Blind, Placebo-Controlled, 52-Week Phase II Study to Evaluate the Efficacy of Intravenous RO7046015 (PRX002) in Participants with Early Parkinson’s Disease with a 52 Week Blinded Extension (PASADENA) Simuni, Tatyana Early Parkinson's Disease
A Longitudinal Evaluation of Disease & Fibrosis Biomarkers in Different Groups of Heart Failure Patients to Enhance the Early Clinical Development of Compounds with Anti-fibrotic Activity in the Heart Shah, Sanjiv J heart failure, MRI, Acute decompensated heart failure , ADHF
Dapagliflozin EFfect on symptoms and bIomarkers iN diabetEs patients with Heart Failure (DEFINE-HF) Mutharasan, R Kannan heart failure, diabetes
REDO-FIRM - Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures Knight, Bradley Paul AF, atrial fibrillation, heart rhythm disorder, arrhythmia, ablation
A multi-centre, randomized, double-blind (sponsor open), placebo-controlled, repeat-dose, proof of mechanism study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and explore efficacy of GSK2330811 in participants with diffuse cutaneous systemic sclerosis Varga, John scleroderma, systemic sclerosis, skin fibrosis, treatment
Understanding Outcomes with the EMBLEM™ S-ICD in Primary Prevention Patients with Low Ejection Fraction Knight, Bradley Paul ICD, Cardiac Defibrillator, heart rhythm disorder, arrhythmia, S-ICD
A prospective, multicenter, single-arm study designed to assess the safety of 3-month dual antiplatelet therapy (DAPT) in subjects at high risk for bleeding undergoing percutaneous coronary intervention (PCI) with the SYNERGY Everolimus-Eluting Platinum Chromium Coronary Stent System (SYNERGY Stent System) Ricciardi, Mark stent, coronary artery disease, CAD, coronary disease
Exercise in Genetic Cardiovascular Conditions: Lifestyle and Exercise in Hypertrophic Cardiomyopathy: “LIVE-HCM”/ Lifestyle and Exercise in Long QT Syndrome: “LIVE-LQTS” Choudhury, Lubna Hypertrophic Cardiomyopathy, HCM, Cardiomyopathy, arrhythmia, Long QT Syndrome, LQTS, exercise
Neuromodulation and Neurorehabilitation for Treatment of Functional Deficits after mTBI plus PTSD Pape, Theresa L Bender L
Temozolomide and Pazopanib Hydrochloride in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors That Cannot Be Removed By Surgery Kircher, Sheetal
Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer Mohindra, Nisha recurrent non-small cell lung cancer, stage IIIB non-small cell lung cancer, stage IV non-small cell lung cancer, adenocarcinoma of the lung, bronchoalveolar cell lung cancer, large cell lung cancer
(xIRB) NCI cIRB - NRG GU002: PHASE II-III TRIAL OF ADJUVANT RADIOTHERAPY AND ANDROGEN DEPRIVATION FOLLOWING RADICAL PROSTATECTOMY WITH OR WITHOUT ADJUVANT DOCETAXEL Sachdev, Sean
Ruxolitinib Prior to Transplant in Patients With Myelofibrosis Adekola, Kehinde Myelofibrosis, Stem cell transplant, Ruxolitinib
Phase I Study of AG-221 in Subjects With Advanced Hematologic Malignancies With an IDH2 Mutation Altman, Jessica K acute myeloid leukemia, AML, myelodysplastic syndrome, MDS, hematologic malignancies, IDH
Language in Primary Progressive Aphasia Mesulam, Marek-Marsel Primary Progressive Aphasia, Semantic Dementia, PPA, Progressive Nonfluent Aphasia, Frontotemporal Dementia, Progressive Aphasia
Asteria Zee, Phyllis C sleep, performance, overnight
A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with an Acute, Complicated Type B Aortic Dissection Malaisrie, S Chris Chris aortic dissection, type B
A multicenter, randomized, placebo-controlled, parallel group, double blind, dose-finding Phase II trial to study the efficacy, safety, pharmacokinetics and pharmacodynamic effects of the oral partial adenosine A1 receptor agonist neladenoson bialanate over 20 weeks in patients with chronic heart failure and preserved ejection fraction Khan, Sadiya Heart Failure, Reduced Ejection Fraction, HFrEF
Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma Chandra, Sunandana
A PHASE 1B, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER, SINGLE ASCENDING DOSE STUDY TO ASSESS THE SAFETY, EFFICACY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF DS-1040B WHEN ADDED TO STANDARD OF CARE ANTICOAGULATION THERAPY IN SUBJECTS WITH ACUTE SUBMASSIVE PULMONARY EMBOLISM Schimmel, Daniel Richard pulmonary embolism, thrombotic disease
S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer Hussain, Maha Prostate cancer, TAK-700, Bicalutamide, S1216, androgen therapy, Phase III
NU 15U06: A Phase 1 Dose-Escalation Study of Intravesical Pembrolizumab and Bacillus Calmette-Guerin (BCG) in Subjects with High Risk and BCG-Refractory Non-Muscle-Invasive Bladder Cancer Meeks, Joshua J
D-Cycloserine for the Treatment of Chronic, Refractory Low Back Pain Schnitzer, Thomas J low back pain, pain , back pain, chronic low back pain
CIRB: SWOG 1602 A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG-Naïve High-Grade Non-Muscle Invasive Bladder Cancer Meeks, Joshua J
DRUG 9785-MA-1010: A Randomized Study of Enzalutamide in Patients with Localized Prostate Cancer Undergoing Active Surveillance (ENACT) Schaeffer, Edward
LIBERTY 2: An International Phase 3 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study to Evaluate Relugolix Co-Administered with and without Low-Dose Estradiol and Norethindrone Acetate in Women with Heavy Menstrual Bleeding Associated with Uterine Fibroids Robins, Jared uterine fibroids, heavy menstrual bleeding, women's health, Relugolix, LIBERTY
A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Safety and Efficacy of VM202 to Treat Chronic Non-healing Foot Ulcers in Diabetic Patients with Concomitant Peripheral Arterial Disease (PAD) Galiano, Robert D diabetic foot ulcer, peripheral artery diseas
Hepatocyte Growth Factor to Improve Functioning in PAD: The HI-PAD Study McDermott, Mary McGrae Douglas
BGJ398 for Patients With Tumors With FGFR Genetic Alterations Chae, Young Kwang Solid tumor malignancy, hematologic malignancy, mutation, translocations, amplifications,, fusions, signature, FGFR, ligand, BGJ398, SIGNATURE
Phase II Trial of HM61713 (BI 1482694) for the Treatment of ≥2nd Line T790M Mutation Positive Adenocarcinoma of the Lung Chae, Young Kwang NSCLC, EGFR-TKI, non small cell lung cancer, HM61713, T790M-positive, lung cancer, BI 1482694, Phase II
Efficacy Evaluation of TheraSphere in Patients With Inoperable Liver Cancer Kulik, Laura M
Diet and Physical Activity Change or Usual Care in Improving Survival in Patients With Previously Treated Stage II, III, or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Shahabi, Shohreh
Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery Halverson, Amy L stage IIA rectal cancer, stage IIIA rectal cancer, stage IIIB rectal cancer
Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer Shahabi, Shohreh
Safety, Tolerability, and Efficacy of TAK-659 in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (AML) Frankfurt, Olga Drug therapy
Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA Mittal, Bharat B
Dose Escalation and Double-blind Study of Veliparib in Combination With Carboplatin and Etoposide in Treatment-naive Extensive Stage Disease Small Cell Lung Cancer Chae, Young Kwang Veliparib, PARP - Poly (ADP) ribose polymerase, ABT-888, Extensive Stage Smal Cell Lung Cancer
Ipilimumab, Nivolumab, and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma Gordon, Leo I I
A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma Agulnik, Mark
Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET Mohindra, Nisha Mirati, MGCD265, MET, NSCLC
DRUG CC-90009-AML-001: A Phase 1, Open-Label, Dose-Finding Study Of Cc-90009, A Novel Cereblon E3 Ligase Modulating Drug, In Subjects With Relapsed Or Refractory Acute Myeloid Leukemia Altman, Jessica K
OT-15-001: A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy Kumthekar, Priya
A Phase 2/3 Multicenter, Open-label, 3-arm, 2-stage Randomized Study of ASP2215 (Gilteritinib), Combination of ASP2215 Plus Azacitidine and Azacitidine Alone in the Treatment of Newly Diagnosed Acute Myeloid Leukemia with FLT3 Mutation in Patients Not Eligible for Intensive Induction Chemotherapy Dinner, Shira
BYL719 + T-DM1 in HER2(+) Metastatic Breast Cancer Pts Who Progress on Prior Trastuzumab & Taxane Tx Gradishar, William J
Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer Mittal, Bharat B stage III squamous cell carcinoma of the larynx, stage III verrucous carcinoma of the larynx, stage IV squamous cell carcinoma of the larynx, stage IV verrucous carcinoma of the larynx, stage III squamous cell carcinoma of the lip and oral cavity, stage IV squamous cell carcinoma of the lip and oral cavity, stage III verrucous carcinoma of the oral cavity, stage IV verrucous carcinoma of the oral cavity, stage III squamous cell carcinoma of the oropharynx, stage IV squamous cell carcinoma of the oropharynx, tongue cancer
LEE011 (Ribociclib) in Combination With Docetaxel Plus Prednisone in mCRPC Hussain, Maha Metastatic, Castration-Resistant
Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects With Moderate to Severe Crohn's Disease Hanauer, Stephen Crohn's Disease
Moxetumomab Pasudotox for Advanced Hairy Cell Leukemia Dinner, Shira Biologic Therapy, Recombinant Immunotoxin, Monoclonal Antibody, Pseudomonas Exotoxin, Targeted Therapy
Breaking Down Financial Barriers: A Pilot Study to Determine the Feasibility, Acceptance, and Effectiveness of In vitro Maturation in Low Resource Populations Robins, Jared in vitro maturation, IVM, low income, infertility, PCOS, pregnancy
A multi-center, double-blind, placebo-controlled Phase 2b study to evaluate the efficacy and safety of macitentan in subjects with heart failure with preserved ejection fraction and pulmonary vascular disease Freed, Benjamin Heart Failure, HFpEF, pulmonary vascular disease
A Prospective Phase II Trial of Neoadjuvant Systemic Chemotherapy Followed by Extirpative Surgery for Patients with High Grade Upper Tract Urothelial Carcinoma Meeks, Joshua J
Transformative Research In Diabetic Nephropathy (TRIDENT) (SP0043185) Isakova, Tamara chronic kidney diease, kidney disease, diabetes, renal biopsy, kidney biopsy, research study, research, study, diabetes mellitus, diabetic nephropathy
A Study to Evaluate the Effect of ALKS 3831 Compared to Olanzapine on Body Weight in Young Adults with Schizophrenia, Schizophreniform, or Bipolar I Disorder Who are Early in Their Illness Rado, Jeffrey Psychosis, Schizophrenia, Schizophreniphorm, Bipolar Type 1, Mania, Olanzapine, Samidorphan, Weight gain, Atypical antipsychotic, ALK3831

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